See all 2326 hotels in St. Charles
- Ameristar Casino Resort and Spa
- Country Inn & Suites by Radisson, St. Charles Historic District
- Drury Plaza Hotel St. Louis St. Charles
- Comfort Suites St Charles - St Louis
- Hampton Inn St. Charles St. Peters
- Hampton Inn & Suites St. Charles Old Town Area
- Best Western Plus The Charles Hotel
- WoodSpring Suites St Louis St Charles
- Country Inn & Suites by Radisson, St. Peters, MO
- Super 8 by Wyndham St Charles
- Holiday Inn Express Hotel and Suites St. Charles by IHG
- Mansion 301 · 1st Capitol Mansion Boutique Hotel - Suite 301
- Spacious home in Historic St. Charles, Near Main Street + self-serve breakfast
- 1st Capitol Mansion - Suite 302
- Black & Gold suite 202 -ADA Room
- Home2 Suites by Hilton St. Charles St.Louis
- Red Roof Inn St Louis - St Charles
- Pear Tree Inn St. Louis Airport
- Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
- Hyatt Regency St. Louis at The Arch
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Pear Tree Inn St. Louis Near Union Station
- The Westin St. Louis
- Marriott St. Louis Grand
- River City Casino & Hotel
- Hilton St. Louis Airport
- Home2 Suites by Hilton St. Louis Downtown
- The Wildwood Hotel
- Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
- Courtyard by Marriott St. Louis Downtown/Convention Center
- Hollywood Casino & Hotel St. Louis
- Drury Inn & Suites St. Louis Union Station
- Moonrise Hotel
- Hilton Pennywell St. Louis at the Arch
- The West End
- Renaissance St. Louis Airport Hotel
- Four Seasons Hotel St Louis
- Hampton Inn & Suites St. Louis at Forest Park
- Forest Park Hotel by MDR
- Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
- DoubleTree by Hilton St. Louis Forest Park
- Best Western St. Louis Inn
- Drury Inn & Suites St. Louis Airport
- Travelodge by Wyndham St. Louis
- Drury Inn & Suites Southwest St. Louis
- Drury Plaza Hotel St. Louis Chesterfield
- Hilton St. Louis Frontenac
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Drury Inn & Suites St. Louis St. Peters
- Aloft St. Louis Cortex
- AC Hotel St. Louis Central West End
- Fairfield Inn & Suites by Marriott St. Louis Chesterfield
- Drury Plaza Hotel St. Louis Creve Coeur
- The Ritz-Carlton, St. Louis
- MainStay Suites St. Louis - Galleria
- Wingate by Wyndham St. Louis Airport
- Pear Tree Inn St. Louis Convention Center
- The Knight Center at Washington University
- Crowne Plaza St. Louis Airport by IHG
- Residence Inn by Marriott St Louis Downtown
- Extended Stay America Suites St Louis St Peters
- Le Méridien St. Louis Clayton
- Hyatt Place St. Louis/Chesterfield
- La Quinta Inn & Suites by Wyndham St. Louis Westport