See all 2276 hotels in Panhandle Plains
- The Big Texan Motel
- Country Inn & Suites by Radisson, Lubbock Southwest, TX
- Cotton Court, by Valencia Hotel Collection
- The Cactus Cove Inn and Suites
- Drury Inn & Suites Amarillo
- Country Inn & Suites by Radisson, Amarillo I-40 West, TX
- La Quinta Inn & Suites by Wyndham Lubbock North
- MCM Eleganté Hotel & Suites
- Yellow City Studios
- Ashmore Inn and Suites
- Atrea Inn Amarillo
- Embassy Suites by Hilton Amarillo Downtown
- Days Inn & Suites by Wyndham Lubbock Medical Center
- Econo Lodge Inn & Suites Abilene East District
- Hyatt Place Amarillo-West
- Days Inn by Wyndham Lubbock South
- Holiday Inn Express & Suites Amarillo by IHG
- Hawthorn Suites by Wyndham Lubbock
- Courtyard by Marriott Amarillo Downtown
- Super 8 by Wyndham Lubbock West
- Baymont by Wyndham Amarillo East
- Hyatt Place Lubbock
- Quality Inn Amarillo East
- Hampton Inn & Suites Lubbock University
- The Barfield, Autograph Collection
- Staybridge Suites Lubbock - University Area by IHG
- Delta Hotels by Marriott Wichita Falls Convention Center
- Courtyard by Marriott Wichita Falls
- My Place Hotel - Amarillo West/ Medical Center, TX
- Best Western North Side Inn
- Days Inn by Wyndham Abilene
- Holiday Inn Express & Suites Lubbock West by IHG
- Holiday Inn Lubbock South by IHG
- Home2 Suites by Hilton Amarillo
- Aloft Lubbock
- Best Western Plus Medical Center
- La Quinta Inn & Suites by Wyndham Lubbock West Medical Centr
- Comfort Inn & Suites Lubbock West
- Spark by Hilton Amarillo East
- Courtyard by Marriott Amarillo West/Medical Center
- La Quinta Inn by Wyndham Amarillo West Medical Center
- Blue Bonnet Suites Extended Stay Lubbock, Texas
- Studio 6 Amarillo, TX – West Medical Center
- La Quinta Inn & Suites by Wyndham Abilene Mall
- Quality Suites Lubbock Southwest
- Microtel Inn & Suites by Wyndham Lubbock
- Four Points by Sheraton Amarillo Central
- Everhome Suites Amarillo West - Medical Center
- Springhill Suites by Marriott Amarillo
- Fairfield Inn & Suites by Marriott Wichita Falls Northwest
- Rodeway Inn Abilene West
- Scottish Inns & Suites
- Motel 6 Amarillo, TX
- Best Western Abilene Inn & Suites
- Holiday Inn Abilene - North College Area by IHG
- Baymont by Wyndham Lubbock - Downtown Civic Center
- Holiday Inn Express Hotel & Suites Lubbock South by IHG
- Country Inn & Suites by Radisson, Lubbock, TX
- Ramada by Wyndham Burkburnett / Wichita Falls
- Best Windsor Inn
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