See all 2276 hotels in Panhandle Plains
- Hilton Garden Inn Amarillo
- Baymont by Wyndham Snyder
- Hampton Inn Wichita Falls Sikes Senter Mall
- Pioneer Pocket Hotel
- Quality Inn
- Quality Inn Dumas
- Super 8 BY Wyndham Lubbock Airport
- La Quinta Inn & Suites by Wyndham Sweetwater East
- Spark by Hilton Amarillo West Medical Center
- Doubletree by Hilton Abilene Downtown Convention Center
- Baymont by Wyndham Abilene
- Hawthorn Extended Stay by Wyndham Amarillo
- American Star Inn
- Fairfield Inn & Suites by Marriott Amarillo Central
- Lone Star Inn by OYO Vernon Texas Hwy 287
- Holiday Inn Express Hotel Suites Lubbock Southwest-Wolfforth by IHG
- Courtyard by Marriott Lubbock
- SureStay Plus Hotel by Best Western Lubbock Medical Center
- Comfort Suites University
- Residence Inn by Marriott Lubbock Southwest
- Holiday Inn Amarillo West Medical Center by IHG
- Hampton Inn & Suites Amarillo East
- Extend-a-Suites - Extended Stay, I-40 Amarillo West
- Holiday Inn Express & Suites Dalhart by IHG
- Red Roof Inn Amarillo West
- Courtyard by Marriott Abilene Southwest/Abilene Mall South
- Hereford Motel
- Holiday Inn Express & Suites Wichita Falls by IHG
- Comfort Suites University
- Motel 6 Snyder, TX
- Extended Stay America Suites Lubbock Southwest
- Sleep Inn & Suites Lubbock West
- Sleep Inn & Suites West Medical Center
- Hampton Inn & Suites Amarillo West
- La Quinta Inn & Suites by Wyndham Dumas
- Days Inn by Wyndham Amarillo East
- Millsap Suites by Pioneer Pocket Hotel
- Holiday Inn Express & Suites Abilene by IHG
- Big Country Hotel & Suites, SureStay Collection by BW
- OYO Hotel Wichita Falls - Downtown
- Guest House Inn
- Spark by Hilton Dumas
- Residence Inn by Marriott Lubbock-University Area
- Holiday Inn Express Hotel & Suites Brownfield by IHG
- Super 8 by Wyndham Abilene North
- Hotel Vernon
- Hilton Garden Inn Abilene
- Spark by Hilton Wichita Falls
- Hampton Inn & Suites Dalhart
- The Westerner - Extended Stay
- Best Western South Plains Inn & Suites
- Best Western Littlefield Inn & Suites
- Motel 6 Wichita Falls, TX - North
- Super 8 by Wyndham Wichita Falls
- Best Western Plus Sweetwater Inn & Suites
- Hampton Inn & Suites Canyon
- Shamrock Country Inn
- Days Inn by Wyndham Dalhart
- Hampton Inn & Suites Childress
- Days Inn by Wyndham Wichita Falls
- Super 8 by Wyndham Plainview
- Econo Lodge Inn & Suites Sweetwater I-20
- Camelot INN
- Home2 Suites by Hilton Abilene
- La Quinta Inn & Suites by Wyndham Pampa
- Fairfield Inn & Suites Amarillo Airport
- Studio 6 Sweetwater, TX
- Super 8 by Wyndham Colorado City
- Super 8 by Wyndham Dumas TX
- Buffalo Inn Canyon
- Best Western Plus Shamrock Inn & Suites