See all 2969 hotels in Upstate South Carolina
- Hilton Greenville
- Embassy Suites Greenville Golf Resort & Conference Center
- Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
- Best Western Plus Clemson Hotel & Conference Center
- Hyatt Place Greenville/Haywood
- Days Inn by Wyndham Anderson
- La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
- Courtyard by Marriott Greenville Haywood Mall
- Drury Inn & Suites Greenville
- Hampton Inn & Suites Greenville-Downtown-RiverPlace
- Best Western Plus Greenville I-385 Inn & Suites
- Aloft Greenville Downtown
- AC Hotel By Marriott Greenville
- Lakeside Lodge Clemson
- The Westin Poinsett Greenville
- Comfort Inn Greenville - Haywood Mall
- Sleep Inn Spartanburg Southwest
- Urban Boutique Hotel, BW Signature Collection
- DoubleTree by Hilton Greenville Woodruff Road
- Homewood Suites by Hilton Greenville Downtown
- Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
- Hampton Inn & Suites Greenville Airport, SC
- Comfort Suites At WestGate Mall
- Woodspring Suites Greenville Airport
- HomeTowne Studios by Red Roof Spartanburg - Asheville Highway
- Spartanburg Marriott
- Greenville Marriott
- Holiday Inn Greenville - Woodruff Road by IHG
- Quality Inn & Suites Greenville - Haywood Mall
- SpringHill Suites by Marriott Greenville Downtown
- Wingate by Wyndham - Greenville-Airport
- Days Inn by Wyndham Greenville
- Hampton Inn Simpsonville
- Motel 6 Greenville, SC
- Holiday Inn Express & Suites Greenville Airport by IHG
- Holiday Inn Express & Suites Greenville - Downtown by IHG
- Fairfield Inn by Marriott Greenville-Spartanburg Airport
- Extended Stay America Premier Suites - Greenville - Spartanburg - I-85
- Courtyard Greenville-Spartanburg by Marriott
- Days Inn by Wyndham Spartanburg Waccamaw
- Quality Inn Clemson near University
- Home2 Suites by Hilton Greenville Downtown
- Quality Inn Clinton - Laurens I-26
- Baymont by Wyndham Greenville Woodruff Rd
- Horizon Inn & Suites
- Quality Inn & Suites Easley - Greenville
- Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
- Tru by Hilton Greenville Woodruff Road
- Courtyard by Marriott Greenville Mauldin
- Best Western Greenville Airport Inn
- Hampton Inn Greenville I-385 - Woodruff Rd.
- Hampton Inn & Suites Seneca-Clemson Area
- Studio 6 Greenville, SC - I-85 Near Downtown
- Comfort Suites Simpsonville - Greenville
- The Abernathy of Clemson
- AC Hotel by Marriott Spartanburg
- Tru by Hilton Seneca Clemson
- Tru by Hilton Spartanburg
- Baymont by Wyndham Easley/Greenville
- Residence Inn by Marriott Greenville Downtown
- Comfort Inn & Suites Greer - Greenville
- Holiday Inn Express & Suites Greenville - Taylors by IHG
- Comfort Inn & Suites Spartanburg North
- Days Inn by Wyndham Seneca / Clemson Area
- Woodspring Suites Anderson North I-85
- Hampton Inn Greer Greenville, SC
- Quality Inn & Suites Greenville near downtown
- Country Inn & Suites by Radisson, Anderson, SC
- Fairfield Inn & Suites by Marriott Greenville Simpsonville
- Microtel Inn & Suites by Wyndham Anderson/Clemson
- Hampton Inn Spartanburg-North I-85
- Rodeway Inn Expo Center
- Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
- Sleep Inn at Greenville Convention Cente