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Amazing DSM to TYS Flight Deals
The cheapest flights to McGhee Tyson were $613 for round trip flights and $228 for one-way flights in the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
DSM
Des Moines
TYS
Knoxville
$613 Roundtrip, found 3 days ago
$613
Roundtrip
found 3 days ago
DSM
Des Moines
TYS
Knoxville
$653 Roundtrip, found 3 days ago
$653
Roundtrip
found 3 days ago
DSM
Des Moines
TYS
Knoxville
$659 Roundtrip, found 3 days ago
$659
Roundtrip
found 3 days ago
DSM
Des Moines
TYS
Knoxville
$669 Roundtrip, found 3 days ago
$669
Roundtrip
found 3 days ago
DSM
Des Moines
TYS
Knoxville
$676 Roundtrip, found 3 days ago
$676
Roundtrip
found 3 days ago
DSM
Des Moines
TYS
Knoxville
$687 Roundtrip, found 3 days ago
$687
Roundtrip
found 3 days ago
Hotels near McGhee Tyson Airport (TYS)
Hilton Knoxville Airport
2001 Alcoa Hwy Alcoa TN
$139 nightly
The price is $159 total per night from Sep 20 to Sep 21
$159 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Meigs Falls and Palace Theater are located nearby.
La Quinta Inn & Suites by Wyndham Knoxville Airport
126 Cusick Road Alcoa TN
$78 nightly
The price is $93 total per night from Sep 20 to Sep 21
$93 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
8.8/10 Excellent! (2,009 reviews)
"Nice hotel with shuttle to the airport."
Reviewed on Sep 8, 2026
Candlewood Suites Knoxville Airport-Alcoa by IHG
176 Cusick Road Alcoa TN
$76 nightly
The price is $90 total per night from Sep 20 to Sep 21
$90 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, an outdoor pool, and a free airport shuttle. Popular attractions Meigs Falls and Palace Theater are located nearby.
Save an average of 15% on thousands of hotels when you're signed in
Best Western Knoxville Airport/Alcoa
162 Cusick Rd Alcoa TN
$73 nightly
The price is $87 total per night from Sep 21 to Sep 22
$87 total
Sep 21 - Sep 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
Comfort Suites Knoxville Airport
140 Cusick Rd Alcoa TN
$86 nightly
The price is $103 total per night from Sep 21 to Sep 22
$103 total
Sep 21 - Sep 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
Fairfield by Marriott Inn & Suites Knoxville Airport Alcoa
1865 PAULING ST Alcoa TN
$130 nightly
The price is $154 total per night from Sep 20 to Sep 21
$154 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions Palace Theater and Capitol Theatre are located nearby.
9.2/10 Wonderful! (464 reviews)
"Excellent stay! Everything was great!"
Reviewed on Sep 7, 2026
Hampton Inn Knoxville - Airport
148 International Ave. Alcoa TN
$98 nightly
The price is $117 total per night from Sep 20 to Sep 21
$117 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
8.6/10 Excellent! (806 reviews)
"Staff was very helpful"
Reviewed on Sep 6, 2026
Quality Inn Alcoa Knoxville
206 Corporate Pl Alcoa TN
$82 nightly
The price is $97 total per night from Oct 4 to Oct 5
$97 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Palace Theater and Capitol Theatre are located nearby.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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