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Lowest round trip fares by airline from Houston and Knoxville

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Cheap flights from Houston to Knoxville

Cheap flights from Houston to Knoxville

Are you ready to book your flight, but feeling nervous about paying too much if the price drops? Don't play the waiting game. Our Best Price Guarantee means if you see a better fare for the same flight, we'll give you the difference in CheapCash, plus a $50 CheapCash bonus, which you can use to save on your hotel reservation.

If you have a frequent flier account, add it to your reservation to earn miles. And don't worry about getting stuck in a middle seat. Choose your seats when you book, so you'll be right where you want to be on departure day.

Save Even More Time and Money With a Knoxville Travel Package

Once your flights are booked, why start all over again searching for a cheap hotel? Book your flight and hotel together, and save yourself more than time and energy. You'll also be able to take advantage of discounts and coupons on your Knoxville vacation that you can't get when you book flights and hotel separately.

Relax in Knoxville With Confidence and Convenience

Going cheap doesn't mean giving up great service. Our agents are available 24/7 to help you find the right cheap flights and hotel, and to answer questions about your trip.

Need to grab a cheap travel deal while you're on the go? Download our mobile app, where you can search and book just like you would on your home computer. Stay in-the-know on great rates on flights from Houston to Knoxville by signing up for exclusive email deals.

Packages from Houston to Knoxville

Hotels in Knoxville

See all 243 Properties in Knoxville
Baymont by Wyndham Knoxville I-75

Baymont by Wyndham Knoxville I-75

6712 Central Avenue Pike, Knoxville, TN
    2.5 out of 5.0
     
     
    2.7 out of 5 (3 reviews)

    Situated in Knoxville, this hotel is within 3 mi (5 km) of Bounce USA, Max Air Trampoline Park, and Knoxville Expo Center. Crown College is 2.9 mi (4.7 km) ...

    Baymont by Wyndham Knoxville I-75$56

    Baymont by Wyndham Knoxville I-75$56
    Red Roof Inn PLUS+ & Suites Knoxville West – Cedar Bluff

    Red Roof Inn PLUS+ & Suites Knoxville West – Cedar Bluff

    208 Market Pl Blvd, Knoxville, TN
      2.5 out of 5.0
       
       
      4.8 out of 5 (4 reviews)

      Situated in the suburbs, this motel is within 9 mi (15 km) of West Town Mall, Pellissippi State Community College, and Willow Creek Golf Club. Knoxville Museum ...

      Red Roof Inn PLUS+ & Suites Knoxville West – Cedar Bluff$56

      Red Roof Inn PLUS+ & Suites Knoxville West – Cedar Bluff$56
      Hyatt Place Knoxville Downtown

      Hyatt Place Knoxville Downtown

      530 S Gay St, Knoxville, TN
        3.0 out of 5.0
         
         
        4.0 out of 5 (1 reviews)

        Located in Downtown Knoxville, this hotel is steps from Fort Loudoun Lake and Tennessee Theatre. Sunsphere Tower and Women's Basketball Hall of Fame are also ...

        Hyatt Place Knoxville Downtown$122

        Hyatt Place Knoxville Downtown$122
        Country Inn & Suites by Radisson, Knoxville at Cedar Bluff, TN

        Country Inn & Suites by Radisson, Knoxville at Cedar Bluff, TN

        9137 Cross Park Drive, Exit 378 - Cedar Bluff Exit, Knoxville, TN
          2.5 out of 5.0
           
           
          3.8 out of 5 (4 reviews)

          Located in Cedar Bluff, this hotel is 3.5 mi (5.7 km) from West Town Mall and within 12 mi (20 km) of Turkey Creek Shopping Center and Willow Creek Golf Club. ...

          Country Inn & Suites by Radisson, Knoxville at Cedar Bluff, TN$94

          Country Inn & Suites by Radisson, Knoxville at Cedar Bluff, TN$94
          Baymont by Wyndham Knoxville/Cedar Bluff

          Baymont by Wyndham Knoxville/Cedar Bluff

          209 Market Place Boulevard, Knoxville, TN
            2.5 out of 5.0
             
             
            3.7 out of 5 (3 reviews)

            Situated in Knoxville, this hotel is 0.1 mi (0.1 km) from Fort Loudoun Lake and 2.5 mi (4 km) from Dead Horse Lake Golf Course. West Town Mall and Turkey Creek ...

            Baymont by Wyndham Knoxville/Cedar Bluff$80

            Baymont by Wyndham Knoxville/Cedar Bluff$80
            The Volunteer Hotel

            The Volunteer Hotel

            1706 Cumberland Ave, Knoxville, TN
              3.5 out of 5.0
               
               
              5.0 out of 5 (1 reviews)

              Located in Downtown Knoxville, this hotel is steps from Fort Loudoun Lake and University of Tennessee. Thompson Boiling Arena and Neyland Stadium are also within ...

              The Volunteer Hotel$93

              The Volunteer Hotel$93
              Best Western Knoxville Suites - Downtown

              Best Western Knoxville Suites - Downtown

              5317 Pratt Rd, Knoxville, TN
                2.5 out of 5.0
                 
                 
                4.0 out of 5 (3 reviews)

                Situated in Knoxville, this hotel is 1.2 mi (2 km) from Knoxville Expo Center and within 6 mi (10 km) of Sunsphere Tower and University of Tennessee. Knoxville ...

                Best Western Knoxville Suites - Downtown$72

                Best Western Knoxville Suites - Downtown$72
                Hilton Knoxville

                Hilton Knoxville

                501 W Church Ave, Knoxville, TN
                  3.5 out of 5.0
                   
                   
                  5.0 out of 5 (1 reviews)

                  Located in Downtown Knoxville, this hotel is within a 5-minute walk of Fort Loudoun Lake, Sunsphere Tower, and Tennessee Theatre. Knoxville Convention Center ...

                  Hilton Knoxville$119

                  Hilton Knoxville$119
                  La Quinta Inn & Suites by Wyndham Knoxville Papermill

                  La Quinta Inn & Suites by Wyndham Knoxville Papermill

                  1317 Kirby Rd, Knoxville, TN
                    2.5 out of 5.0
                     
                     
                    5.0 out of 5 (3 reviews)

                    Located in the heart of Knoxville, this hotel is 0.1 mi (0.1 km) from Fort Loudoun Lake and 2.7 mi (4.4 km) from West Town Mall. Bearden Antique Mall is 1.9 ...

                    La Quinta Inn & Suites by Wyndham Knoxville Papermill$99

                    La Quinta Inn & Suites by Wyndham Knoxville Papermill$99
                    Drury Inn & Suites Knoxville West

                    Drury Inn & Suites Knoxville West

                    209 Advantage Place, Knoxville, TN
                      3.0 out of 5.0
                       
                       
                      5.0 out of 5 (1 reviews)

                      Situated in Knoxville, this hotel is 0.1 mi (0.1 km) from Fort Loudoun Lake and 2.4 mi (3.8 km) from Dead Horse Lake Golf Course. West Town Mall and Turkey Creek ...

                      Drury Inn & Suites Knoxville West$95

                      Drury Inn & Suites Knoxville West$95
                      Map

                      *Savings based on all holiday package bookings with Flight + Hotel on CheapTickets.com from January through December 2017, as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages. For Free Flight or 100% Off Flight deals, package savings is greater than or equal to the current cost of one component, when both are priced separately.

                      *Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.