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Amazing DSM to TYS Flight Deals
The cheapest flights to McGhee Tyson were $614 for round trip flights and $194 for one-way flights in the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
DSM
Des Moines
TYS
Knoxville
$614 Roundtrip, found 1 day ago
$614
Roundtrip
found 1 day ago
DSM
Des Moines
TYS
Knoxville
$633 Roundtrip, found 1 day ago
$633
Roundtrip
found 1 day ago
DSM
Des Moines
TYS
Knoxville
$691 Roundtrip, found 1 day ago
$691
Roundtrip
found 1 day ago
DSM
Des Moines
TYS
Knoxville
$836 Roundtrip, found 1 day ago
$836
Roundtrip
found 1 day ago
Hotels near McGhee Tyson Airport (TYS)
La Quinta Inn & Suites by Wyndham Knoxville Airport
126 Cusick Road Alcoa TN
$74 nightly
The price is $88 total per night from Nov 23 to Nov 24
$88 total
Nov 23 - Nov 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
Hilton Knoxville Airport
2001 Alcoa Hwy Alcoa TN
$144 nightly
The price is $165 total per night from Nov 22 to Nov 23
$165 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Meigs Falls and Palace Theater are located nearby.
9.2/10 Wonderful! (1,000 reviews)
"Helpful staff"
Reviewed on Oct 22, 2026
Best Western Knoxville Airport/Alcoa
162 Cusick Rd Alcoa TN
$70 nightly
The price is $83 total per night from Nov 23 to Nov 24
$83 total
Nov 23 - Nov 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
8.6/10 Excellent! (1,008 reviews)
"Our room was unsatisfactory: something wrong with fan on A/C unit made a loud sound and couldn't sleep and the room smelled funny. There was also a little mold in the shower and a sizable chip in the tub enamel. I asked for a new room but they were booked. Manager was supposed to contact me the next ..."
Reviewed on Oct 23, 2026
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Candlewood Suites Knoxville Airport-Alcoa by IHG
176 Cusick Road Alcoa TN
$71 nightly
The price is $84 total per night from Nov 24 to Nov 25
$84 total
Nov 24 - Nov 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, an outdoor pool, and a free airport shuttle. Popular attractions Meigs Falls and Palace Theater are located nearby.
Courtyard Knoxville Airport Alcoa
141 Furrow Way Alcoa TN
$107 nightly
The price is $127 total per night from Nov 22 to Nov 23
$127 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our reviews. Popular attractions Meigs Falls and Palace Theater are located nearby.
Hampton Inn Knoxville - Airport
148 International Ave. Alcoa TN
$110 nightly
The price is $130 total per night from Oct 31 to Nov 1
$130 total
Oct 31 - Nov 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
Comfort Suites Knoxville Airport
140 Cusick Rd Alcoa TN
$79 nightly
The price is $94 total per night from Nov 23 to Nov 24
$94 total
Nov 23 - Nov 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
Fairfield by Marriott Inn & Suites Knoxville Airport Alcoa
1865 PAULING ST Alcoa TN
$129 nightly
The price is $153 total per night from Oct 25 to Oct 26
$153 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, an outdoor pool, and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. Popular attractions Palace Theater and Capitol Theatre are located nearby.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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