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Amazing DSM to TYS Flight Deals
The cheapest flights to McGhee Tyson were $361 for round trip flights and $230 for one-way flights in the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
DSM
Des Moines
TYS
Knoxville
$361 Roundtrip, found 6 days ago
$361
Roundtrip
found 6 days ago
DSM
Des Moines
TYS
Knoxville
$393 Roundtrip, found 6 days ago
$393
Roundtrip
found 6 days ago
DSM
Des Moines
TYS
Knoxville
$397 Roundtrip, found 6 days ago
$397
Roundtrip
found 6 days ago
DSM
Des Moines
TYS
Knoxville
$398 Roundtrip, found 6 days ago
$398
Roundtrip
found 6 days ago
DSM
Des Moines
TYS
Knoxville
$403 Roundtrip, found 6 days ago
$403
Roundtrip
found 6 days ago
DSM
Des Moines
TYS
Knoxville
$404 Roundtrip, found 6 days ago
$404
Roundtrip
found 6 days ago
Hotels near McGhee Tyson Airport (TYS)

La Quinta Inn & Suites by Wyndham Knoxville Airport
126 Cusick Road Alcoa TN
$76 nightly
The price is $90 total per night from Mar 15 to Mar 16
$90 total
Mar 15 - Mar 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
8.8/10 Excellent! (1,783 reviews)
Room was very clean, beds and bathroom. The entire place looked clean as we walked in.
Reviewed on Mar 10, 2026

Hilton Knoxville Airport
2001 Alcoa Hwy Alcoa TN
$132 nightly
The price is $151 total per night from Apr 5 to Apr 6
$151 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Meigs Falls and Palace Theater are located nearby.
9.2/10 Wonderful! (1,009 reviews)
Great location and super convenient parking area. You can simply walk from airport to hotel. However, the staff needs major training. I have stayed here multiple times and have had multiple challenges. Last time, I was traveling with a young single female assistant from UK. She had her own room and ...
Reviewed on Mar 7, 2026

Best Western Knoxville Airport/Alcoa
162 Cusick Rd Alcoa TN
$66 nightly
The price is $78 total per night from Mar 22 to Mar 23
$78 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
8.4/10 Very Good! (1,004 reviews)
Property was very clean and the breakfast was pretty good.
Reviewed on Mar 9, 2026
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Tru by Hilton Alcoa Knoxville Airport
125 FURROW WAY Alcoa TN
$83 nightly
The price is $98 total per night from Mar 22 to Mar 23
$98 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Meigs Falls and Palace Theater are located nearby.
8.6/10 Excellent! (685 reviews)
Check in was very smooth. Our room was perfect. I asked for a later check out (at 12:30) and they were very accommodating. I would highly recommend this property.
Reviewed on Mar 10, 2026

Candlewood Suites Knoxville Airport-Alcoa by IHG
176 Cusick Road Alcoa TN
$78 nightly
The price is $93 total per night from Mar 15 to Mar 16
$93 total
Mar 15 - Mar 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, an outdoor pool, and a free airport shuttle. Popular attractions Meigs Falls and Palace Theater are located nearby.
8.4/10 Very Good! (627 reviews)
Quick shuttle ride with short wait. Accommodating staff.
Reviewed on Mar 7, 2026

Courtyard Knoxville Airport Alcoa
141 Furrow Way Alcoa TN
$94 nightly
The price is $112 total per night from Apr 5 to Apr 6
$112 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Meigs Falls and Palace Theater are located nearby.
8.8/10 Excellent! (739 reviews)
Stay was great! Was allowed to leave my vehicle at the hotel and they shuttled us to the airport!
Reviewed on Feb 13, 2026

Comfort Suites Knoxville Airport
140 Cusick Rd Alcoa TN
$75 nightly
The price is $89 total per night from Mar 15 to Mar 16
$89 total
Mar 15 - Mar 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
7.8/10 Good! (771 reviews)
First thing I saw was a dirty front door then as I walked in the vending machine was so dirty I would get nothing from it..Walking to our room you could see the walls being dirty as well as the doors..Our room..Bathroom in the corner you could see a patch of mold and they tried to paint over it. ...
Reviewed on Mar 10, 2026

Hampton Inn Knoxville - Airport
148 International Ave. Alcoa TN
$95 nightly
The price is $113 total per night from Apr 4 to Apr 5
$113 total
Apr 4 - Apr 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
8.6/10 Excellent! (765 reviews)
The room was clean and the staff was helpful!
Reviewed on Mar 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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