Get more for your budget and save up to 50% off select Secret Bargain hotels
Get even more value with CheapTickets Price Guarantee!
Change your flight without a fee on select flights
Find Your Perfect Flight
Amazing DSM to TYS Flight Deals
The cheapest flights to McGhee Tyson were $312 for round trip flights and $107 for one-way flights in the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
DSM
Des Moines
TYS
Knoxville
$312 Roundtrip, found 5 days ago
$312
Roundtrip
found 5 days ago
DSM
Des Moines
TYS
Knoxville
$325 Roundtrip, found 5 days ago
$325
Roundtrip
found 5 days ago
DSM
Des Moines
TYS
Knoxville
$347 Roundtrip, found 5 days ago
$347
Roundtrip
found 5 days ago
DSM
Des Moines
TYS
Knoxville
$357 Roundtrip, found 5 days ago
$357
Roundtrip
found 5 days ago
DSM
Des Moines
TYS
Knoxville
$360 Roundtrip, found 5 days ago
$360
Roundtrip
found 5 days ago
DSM
Des Moines
TYS
Knoxville
$362 Roundtrip, found 5 days ago
$362
Roundtrip
found 5 days ago
Hotels near McGhee Tyson Airport (TYS)
Hilton Knoxville Airport
2001 Alcoa Hwy Alcoa TN
$133 nightly
The price is $153 total per night from May 10 to May 11
$153 total
May 10 - May 11
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Meigs Falls and Palace Theater are located nearby.
9.2/10 Wonderful! (1,002 reviews)
Room was not clean, bed had large chunk of visible human hair on it and the bathroom sink had hair in it as well. I had to check out that night without laying on the bed. Bad experience. Told the staff at the reception and the situation was not addressed.
Reviewed on Apr 24, 2026
La Quinta Inn & Suites by Wyndham Knoxville Airport
126 Cusick Road Alcoa TN
$74 nightly
The price is $88 total per night from May 3 to May 4
$88 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
8.8/10 Excellent! (1,850 reviews)
The elevator was broken but otherwise it was fine.
Reviewed on Apr 25, 2026
Best Western Knoxville Airport/Alcoa
162 Cusick Rd Alcoa TN
$70 nightly
The price is $83 total per night from May 3 to May 4
$83 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
8.4/10 Very Good! (1,001 reviews)
Worked well for a brief overnight stay for the price.
Reviewed on Apr 19, 2026
Save an average of 15% on thousands of hotels when you're signed in
Tru by Hilton Alcoa Knoxville Airport
125 FURROW WAY Alcoa TN
$89 nightly
The price is $106 total per night from May 17 to May 18
$106 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Meigs Falls and Palace Theater are located nearby.
8.8/10 Excellent! (703 reviews)
Great overnight stay for airport
Reviewed on Apr 25, 2026
Candlewood Suites Knoxville Airport-Alcoa by IHG
176 Cusick Road Alcoa TN
$67 nightly
The price is $80 total per night from May 10 to May 11
$80 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, an outdoor pool, and a free airport shuttle. Popular attractions Meigs Falls and Palace Theater are located nearby.
8.4/10 Very Good! (646 reviews)
Delightful and helpful staff. Expectations met!
Reviewed on Apr 22, 2026
Courtyard Knoxville Airport Alcoa
141 Furrow Way Alcoa TN
$112 nightly
The price is $133 total per night from May 3 to May 4
$133 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Meigs Falls and Palace Theater are located nearby.
8.8/10 Excellent! (751 reviews)
I made this reservation last minute but, found a hotel fast and reserved one of the empty rooms for us. Very clean property. It actually seems good when you walked in. Will stay again when needed.
Reviewed on Apr 15, 2026
Comfort Suites Knoxville Airport
140 Cusick Rd Alcoa TN
$77 nightly
The price is $91 total per night from May 17 to May 18
$91 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Meigs Falls and Fort Loudoun Lake are located nearby.
7.8/10 Good! (788 reviews)
First off I requested a first floor room because I walk with a cane. They put me on the top floor in the room farthest away from the elevator. Then they blocked off ALL handicap parking to paint so I could not use it the entire time. The third morning there was a guy painting outside of our window ...
Reviewed on Apr 24, 2026
Mainstay Suites Knoxville Airport
361 Fountain View Cir Alcoa TN
$80 nightly
The price is $95 total per night from Apr 26 to Apr 27
$95 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Palace Theater and Capitol Theatre are located nearby.
7.8/10 Good! (725 reviews)
Hotel is older, but everyone was friendly.
Reviewed on Apr 24, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Picks
- Maryville Hotels
- Hotels with Restaurants in Farragut
- Hotels with Suites in Maryville
- Cabin Rentals in Farragut
- Business Hotels in Maryville
- Hotels with Kitchenettes in Alcoa
- 5 Star Hotels in Alcoa
- Golf Resorts & in Alcoa
- 5 Star Hotels in Downtown Knoxville
- Hotels with Kitchenettes in Maryville
- Hotels near Neyland Stadium
- Hotels with Airport Transfers in Maryville
- Hotels near McGhee Tyson
- Hotels near Dead Horse Lake Golf Course
- Hotels on the River in Downtown Knoxville
- Ski Resorts & in Farragut
- Hotels with Pools in Maryville
- Luxury Hotels in Maryville
- Hotels with Hot Tubs in Farragut
- 5 Star Hotels in Farragut
- Hotels with Suites in Farragut
- Business Hotels in Downtown Knoxville
- Rivertrace Hotels
- Villas in Farragut
- Business Hotels in Alcoa
- Cheap Hotels in Maryville
- Hotels with a Wedding Venue in Alcoa
- Hotels with Bars in Farragut
- 4 Star Hotels in Downtown Knoxville
- B&B in Maryville
- Cabin Rentals in Alcoa
- Adventure Sport Hotels in Downtown Knoxville
- 4 Star Hotels in Alcoa
- Hotels with Shopping in Farragut
- Hotels with Shopping in Alcoa
- Extended Stay America Hotels in Alcoa
- Hotels with Free Breakfast in Farragut
- Villas in Maryville
- Hotels with Free Parking in Alcoa
- Historic Hotels in Downtown Knoxville
- Residences in Maryville
- 4 Star Hotels in Maryville
- Red Roof Inn Hotels in Farragut
- Knoxville Hotels
- Romantic Getaways & Hotels in Alcoa
- Motels in Alcoa
- Hotels with Balconies in Maryville
- La Quinta Inn & Suites Hotels in Cedar Bluff
- Romantic Getaways & Hotels in Maryville
- Farmstay in Maryville
- Hotels with Air Conditioning in Alcoa
- 4 Star Hotels in Farragut
- Hotels on the Lake in Alcoa
- Hotels with Hot Tubs in Alcoa
- Hotels with Pools in Alcoa
- Hotels with an Indoor Pool in Alcoa
- 5 Star Hotels in Maryville
- Hotels with Balconies in Downtown Knoxville
- Flights from Sacramento (SMF) to Knoxville (TYS)
- Flights from McGhee Tyson
- Flights from Fort Wayne to Knoxville
- Flights from Tulsa to Knoxville
- Flights from Hattiesburg to Knoxville
- Flights from San Diego to Alcoa
- Flights from Shreveport to Knoxville
- Flights from Chicago to Knoxville
- Flights from Fort Smith to Knoxville
- Flights from Knoxville
- Flights from Houston to Knoxville
- Flights from Burbank to Knoxville
- Flights to Knoxville
- Flights from Cleveland to Knoxville
- Flights from Providence to Knoxville
- Flights from Philadelphia to Knoxville
- Flights from Newark to Knoxville
- Flights from Des Moines to Knoxville
- Flights from Indianapolis to Knoxville
- Flights from Dallas to Knoxville
- Flights to Farragut
- Flights to McGhee Tyson
- Flights from Cincinnati to Knoxville
- Flights from Albuquerque to Knoxville
- Flights from Washington to Knoxville
- Flights from Buffalo to Knoxville
- Flights from Omaha to Knoxville
- Flights from Alcoa
- Flights from San Diego (SAN) to Knoxville (TYS)
- Flights from Pittsburgh (PIT) to Knoxville (TYS)
- Flights from South Bend to Knoxville
- Flights from Montego Bay to Knoxville
- Flights from Alexandria to Knoxville
- Flights from Tampa (TPA) to Knoxville (TYS)
- Flights from Philadelphia (PHL) to Knoxville (TYS)
- Flights to Alcoa
- Flights from New York to Knoxville