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Featured Tenderloin Spa Resorts & Hotels

Hotel Nikko San Francisco

Hotel Nikko San Francisco

4.5 out of 5
222 Mason St San Francisco CA
$191 nightly
The price is $225 total per night
$225 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Hotel Nikko San Francisco, you'll be centrally located in San Francisco, just a 4-minute walk from Union Square and 14 minutes by foot from Moscone Convention Center.
Pool
Pet friendly
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
$157 nightly
The price is $185 total per night
$185 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Hilton San Francisco Union Square places you in the heart of San Francisco, within a 5-minute drive of Westfield San Francisco Centre and Ferry Building.
Pool
Pet friendly
The Marker Union Square San Francisco

The Marker Union Square San Francisco

4 out of 5
501 Geary St San Francisco CA
$132 nightly
The price is $155 total per night
$155 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at The Marker Union Square San Francisco places you in the heart of San Francisco, within a 5-minute drive of Moscone Convention Center and Lombard Street.
Pet friendly
Restaurant
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

4 out of 5
55 Cyril Magnin St San Francisco CA
$164 nightly
The price is $193 total per night
$193 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Parc 55 San Francisco - A Hilton Hotel places you in the heart of San Francisco, steps from Westfield San Francisco Centre and a 4-minute drive from Lombard Street.
Pet friendly
Free WiFi
The Clift Royal Sonesta San Francisco

The Clift Royal Sonesta San Francisco

4 out of 5
495 Geary St San Francisco CA
$182 nightly
The price is $214 total per night
$214 total
Dec 25 - Dec 26
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at The Clift Royal Sonesta San Francisco in San Francisco (Union Square), you'll be steps from SHN Curran Theatre and 7 minutes by foot from Grace Cathedral.
Pet friendly
Free WiFi
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
$149 nightly
The price is $176 total per night
$176 total
Dec 10 - Dec 11
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Handlery Union Square Hotel, you'll be centrally located in San Francisco, steps from Union Square and 14 minutes by foot from Moscone Convention Center.
Pool
Pet friendly
Hotel Spero, Vignette Collection by IHG

Hotel Spero, Vignette Collection by IHG

4 out of 5
405 Taylor St San Francisco CA
$142 nightly
The price is $167 total per night
$167 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Centrally located in San Francisco, Hotel Spero, Vignette Collection by IHG is within a 15-minute walk of Asian Art Museum of San Francisco and San Francisco Museum of Modern Art.
Pet friendly
Restaurant
COVA Hotel

COVA Hotel

2.5 out of 5
655 Ellis Street San Francisco CA
With a stay at COVA Hotel, you'll be centrally located in San Francisco, within a 5-minute drive of Moscone Convention Center and Oracle Park.
Breakfast included
Pet friendly
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Tenderloin hotels essential information

Accommodation
4,691 hotels
Lowest Price
$155
Highest Price
$225
Popular hotels
Hotel Nikko San Francisco, Hilton San Francisco Union Square, The Marker Union Square San Francisco, Parc 55 San Francisco - A Hilton Hotel, The Clift Royal Sonesta San Francisco, Handlery Union Square Hotel, Hotel Spero, Vignette Collection by IHG, COVA Hotel

Most Recent Tenderloin Hotel Reviews

Hyatt Place San Francisco Downtown

Hyatt Place San Francisco Downtown

5 out of 5
Posted 1 day ago
CheapTickets Verified Review
"The breakfast was delicious but it is 14.99 per person. The room was clean and had a nice view of city buildings. Staff was accommodating. "
A verified traveler stayed at Hyatt Place San Francisco Downtown
Hyatt Place San Francisco Downtown

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