See all 4657 hotels in Rancho Santa Margarita
- Ayres Hotel & Spa Mission Viejo – Lake Forest
- The Hills Hotel
- Hilton Orange County/Costa Mesa
- Marriott Irvine Spectrum
- Residence Inn Tustin Orange County
- Courtyard by Marriott John Wayne Airport/Orange County
- Residence Inn by Marriott Costa Mesa Newport Beach
- Homewood Suites By Hilton Irvine John Wayne Airport
- SpringHill Suites by Marriott Irvine
- Hampton Inn and Suites Santa Ana/Orange County Airport
- Fairfield Inn & Suites Riverside Corona/Norco