Best Flight From Lambert-St. Louis Intl. To EYW

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Amazing STL to EYW Flight Deals

The cheapest flights to Key West Intl. were $452 for round trip flights and $348 for one-way flights in the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Mar 20 - Wed, Mar 24
STL
St. Louis
EYW
Key West
$452 Roundtrip, found 3 days ago
$452
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Mar 20 from St. Louis to Key West, returning Wed, Mar 24, priced at $452 found 3 days ago
Sat, Mar 20 - Wed, Mar 24
STL
St. Louis
EYW
Key West
$477 Roundtrip, found 3 days ago
$477
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Mar 20 from St. Louis to Key West, returning Wed, Mar 24, priced at $477 found 3 days ago
Sat, Mar 20 - Wed, Mar 24
STL
St. Louis
EYW
Key West
$502 Roundtrip, found 3 days ago
$502
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Mar 20 from St. Louis to Key West, returning Wed, Mar 24, priced at $502 found 3 days ago
Sat, Mar 20 - Wed, Mar 24
STL
St. Louis
EYW
Key West
$528 Roundtrip, found 3 days ago
$528
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Mar 20 from St. Louis to Key West, returning Wed, Mar 24, priced at $528 found 3 days ago
Sat, Mar 20 - Wed, Mar 24
STL
St. Louis
EYW
Key West
$542 Roundtrip, found 3 days ago
$542
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Mar 20 from St. Louis to Key West, returning Wed, Mar 24, priced at $542 found 3 days ago
Sat, Mar 20 - Wed, Mar 24
STL
St. Louis
EYW
Key West
$553 Roundtrip, found 3 days ago
$553
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Mar 20 from St. Louis to Key West, returning Wed, Mar 24, priced at $553 found 3 days ago

Hotels near Key West Intl. Airport (EYW)

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
The price is $263 total per night from Oct 4 to Oct 5
$263 total
per night
Oct 4 - Oct 5
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Duval Street and Smathers Beach are located nearby.
Opens in a new windowHyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
The price is $156 total per night from Sep 22 to Sep 23
$156 total
per night
Sep 22 - Sep 23
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions Duval Street and Smathers Beach are located nearby.
9/10 Wonderful! (1,492 reviews)
"Clean, comfortable, and friendly staff."

Reviewed on Sep 9, 2026

Opens in a new windowHampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
The price is $150 total per night from Sep 27 to Sep 28
$150 total
per night
Sep 27 - Sep 28
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Duval Street and Smathers Beach are located nearby.
8.4/10 Very Good! (1,090 reviews)
"We arrive early and our room was ready,clean and spacious, personnal very attentive. Great Stay"

Reviewed on Sep 8, 2026

Opens in a new windowDoubleTree Resort by Hilton Grand Key - Key West
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Beachside Resort & Residences

Beachside Resort & Residences

3.5 out of 5
3841 N Roosevelt Blvd Key West FL
The price is $212 total per night from Sep 10 to Sep 11
$212 total
per night
Sep 10 - Sep 11
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 2 restaurants, and a private beach. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Duval Street and Smathers Beach are located nearby.
8.6/10 Excellent! (2,503 reviews)
"Our stay was excellent! Everyone was super nice"

Reviewed on Sep 9, 2026

Opens in a new windowBeachside Resort & Residences
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd Key West FL
The price is $263 total per night from Sep 23 to Sep 24
$263 total
per night
Sep 23 - Sep 24
Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the pool and the restaurant in our reviews. Popular attractions Duval Street and Smathers Beach are located nearby.
8.8/10 Excellent! (1,806 reviews)
"close to beach"

Reviewed on Sep 9, 2026

Opens in a new windowMargaritaville Beach House Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
The price is $180 total per night from Sep 10 to Sep 11
$180 total
per night
Sep 10 - Sep 11
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Duval Street and Smathers Beach are located nearby.
8.6/10 Excellent! (2,660 reviews)
"I decided to stay at this hotel with my girlfriend to celebrate our anniversary. I made reservations for a suite because I wanted us to be comfortable and have the best accommodations possible. I truly thought this would be the perfect place for us to have an unforgettable time together while celebrating ..."

Reviewed on Sep 9, 2026

Opens in a new windowBlue Flamingo Resort Key West
Hilton Garden Inn Key West / The Keys Collection

Hilton Garden Inn Key West / The Keys Collection

3.5 out of 5
3850 N Roosevelt Blvd Key West FL
The price is $156 total per night from Sep 16 to Sep 17
$156 total
per night
Sep 16 - Sep 17
Book a stay at this business-friendly hotel in Key West. Enjoy 2 restaurants, breakfast (surcharge), and a free area shuttle. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Duval Street and Smathers Beach are located nearby.
8.2/10 Very Good! (1,314 reviews)
"Didn’t love this Hilton. Felt more like a motel with a pool. Would not stay here again."

Reviewed on Sep 9, 2026

Opens in a new windowHilton Garden Inn Key West / The Keys Collection
Havana Cabana at Key West

Havana Cabana at Key West

4 out of 5
3420 N. Roosevelt Blvd Key West FL
The price is $187 total per night from Sep 24 to Sep 25
$187 total
per night
Sep 24 - Sep 25
Book a stay at this business-friendly hotel in Key West. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the helpful staff in our reviews. Popular attractions Duval Street and Smathers Beach are located nearby.
9/10 Wonderful! (1,852 reviews)
"Everything was absolutely wonderful and so completely peaceful. I would definitely go again 😁"

Reviewed on Sep 9, 2026

Opens in a new windowHavana Cabana at Key West
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.