Best Flight From Detroit Metropolitan Wayne County To SAN

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Amazing DTW to SAN Flight Deals

The cheapest flights to San Diego Intl. were $242 for round trip flights and $123 for one-way flights in the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Oct 21 - Sat, Oct 24
DTW
Detroit
SAN
San Diego
$242 Roundtrip, found 4 days ago
$242
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, Oct 21 from Detroit to San Diego, returning Sat, Oct 24, priced at $242 found 4 days ago
Mon, Nov 2 - Fri, Nov 6
DTW
Detroit
SAN
San Diego
$254 Roundtrip, found 3 hours ago
$254
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Mon, Nov 2 from Detroit to San Diego, returning Fri, Nov 6, priced at $254 found 3 hours ago
Wed, Oct 21 - Sat, Oct 24
DTW
Detroit
SAN
San Diego
$262 Roundtrip, found 4 days ago
$262
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, Oct 21 from Detroit to San Diego, returning Sat, Oct 24, priced at $262 found 4 days ago
Mon, Nov 2 - Fri, Nov 6
DTW
Detroit
SAN
San Diego
$269 Roundtrip, found 3 hours ago
$269
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Mon, Nov 2 from Detroit to San Diego, returning Fri, Nov 6, priced at $269 found 3 hours ago
Sun, Nov 1 - Thu, Nov 5
DTW
Detroit
SAN
San Diego
$277 Roundtrip, found 3 hours ago
$277
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Sun, Nov 1 from Detroit to San Diego, returning Thu, Nov 5, priced at $277 found 3 hours ago
Sun, Nov 1 - Thu, Nov 5
DTW
Detroit
SAN
San Diego
$280 Roundtrip, found 3 hours ago
$280
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Sun, Nov 1 from Detroit to San Diego, returning Thu, Nov 5, priced at $280 found 3 hours ago

Hotels near San Diego Intl. Airport (SAN)

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$213 nightly
The price is $245 total per night from Sep 27 to Sep 28
$245 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
Opens in a new windowSheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Sep 28 to Sep 29
$211 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
8.4/10 Very Good! (6,305 reviews)
"It was very clean"

Reviewed on Sep 22, 2026

Opens in a new windowWyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
$103 nightly
The price is $119 total per night from Sep 29 to Sep 30
$119 total
Sep 29 - Sep 30
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.
8.4/10 Very Good! (2,937 reviews)
"Great for family!"

Reviewed on Sep 22, 2026

Opens in a new windowHandlery Hotel
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Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
$85 nightly
The price is $97 total per night from Sep 23 to Sep 24
$97 total
Sep 23 - Sep 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.
8/10 Very Good! (3,940 reviews)
"Property is old outdated. Room smell moldy and bathroom mildew. The only thing I like is free parking."

Reviewed on Sep 22, 2026

Opens in a new windowBest Western Seven Seas
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$286 nightly
The price is $332 total per night from Sep 27 to Sep 28
$332 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the helpful staff in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
9/10 Wonderful! (2,873 reviews)
"The pictures on this website are terrible. I was extremely hesitant, but because it was a Hyatt location. I decided to go with my gut because I’ve stayed at Hyatt before. When I arrived at the hotel did not disappoint. Everything was amazing. If you’re thinking to book a room at this hotel do it. ..."

Reviewed on Sep 22, 2026

Opens in a new windowManchester Grand Hyatt San Diego
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
$179 nightly
The price is $208 total per night from Oct 20 to Oct 21
$208 total
Oct 20 - Oct 21
Total with taxes and fees
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
8.6/10 Excellent! (2,664 reviews)
"I enjoy staying at Historical Hotels that have been redone. This is no exception. The room was very roomy and Mouse Quiet, the only thing I ever heard was an occasional Plane flying over. The only thing I can say in a negative is the sheets on the bed were kind of scratchy. Maybe they were new and ..."

Reviewed on Sep 22, 2026

Opens in a new windowThe Sofia Hotel
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
$182 nightly
The price is $209 total per night from Sep 27 to Sep 28
$209 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in our reviews. Popular attractions Port of San Diego and Hotel del Coronado are located nearby.
9.2/10 Wonderful! (3,954 reviews)
"Located close to the marina's."

Reviewed on Sep 22, 2026

Opens in a new windowBay Club Hotel & Marina
The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld

2.5 out of 5
San Diego CA
$97 nightly
The price is $111 total per night from Oct 5 to Oct 6
$111 total
Oct 5 - Oct 6
Total with taxes and fees
Book a stay at this golf hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Bay and San Diego Zoo are located nearby.
8/10 Very Good! (757 reviews)
"Everything is very good, only the WiFi service did not work at all and tv."

Reviewed on Sep 22, 2026

Opens in a new windowThe Alcala Hotel Mission Valley/Seaworld
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.