Best Flight From Portland Intl. To SAN

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Amazing PDX to SAN Flight Deals

The cheapest flights to San Diego Intl. were $137 for round trip flights and $70 for one-way flights in the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Oct 14 - Mon, Oct 19
PDX
Portland
SAN
San Diego
$137 Roundtrip, found 1 day ago
$137
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Oct 14 from Portland to San Diego, returning Mon, Oct 19, priced at $137 found 1 day ago
Wed, Sep 30 - Thu, Oct 1
PDX
Portland
SAN
San Diego
$139 Roundtrip, found 12 hours ago
$139
Roundtrip
found 12 hours ago
Select Southwest Airlines flight, departing Wed, Sep 30 from Portland to San Diego, returning Thu, Oct 1, priced at $139 found 12 hours ago
Wed, Oct 14 - Mon, Oct 19
PDX
Portland
SAN
San Diego
$142 Roundtrip, found 1 day ago
$142
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Wed, Oct 14 from Portland to San Diego, returning Mon, Oct 19, priced at $142 found 1 day ago
Wed, Oct 14 - Mon, Oct 19
PDX
Portland
SAN
San Diego
$144 Roundtrip, found 1 day ago
$144
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Wed, Oct 14 from Portland to San Diego, returning Mon, Oct 19, priced at $144 found 1 day ago
Wed, Oct 14 - Mon, Oct 19
PDX
Portland
SAN
San Diego
$147 Roundtrip, found 1 day ago
$147
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Oct 14 from Portland to San Diego, returning Mon, Oct 19, priced at $147 found 1 day ago
Wed, Sep 30 - Thu, Oct 1
PDX
Portland
SAN
San Diego
$149 Roundtrip, found 12 hours ago
$149
Roundtrip
found 12 hours ago
Select Southwest Airlines flight, departing Wed, Sep 30 from Portland to San Diego, returning Thu, Oct 1, priced at $149 found 12 hours ago

Hotels near San Diego Intl. Airport (SAN)

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$213 nightly
The price is $245 total per night from Sep 27 to Sep 28
$245 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
8.6/10 Excellent! (3,680 reviews)
"Great location and amazing property with pool and restaurant. Close to the airport with free shuttle. Great view of the harbour"

Reviewed on Sep 10, 2026

Opens in a new windowSheraton San Diego Resort
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$276 nightly
The price is $320 total per night from Sep 11 to Sep 12
$320 total
Sep 11 - Sep 12
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the helpful staff in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
9/10 Wonderful! (2,834 reviews)
"When visiting San Diego, I’ve made a few mistakes selecting hotels until I found Manchester Grand Hyatt. This hotel is amazing and extremely welcoming to children and pets!"

Reviewed on Sep 10, 2026

Opens in a new windowManchester Grand Hyatt San Diego
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Sep 20 to Sep 21
$211 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
Opens in a new windowWyndham San Diego Bayside
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Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
$201 nightly
The price is $231 total per night from Sep 13 to Sep 14
$231 total
Sep 13 - Sep 14
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in our reviews. Popular attractions Port of San Diego and Hotel del Coronado are located nearby.
Opens in a new windowBay Club Hotel & Marina
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
$166 nightly
The price is $193 total per night from Sep 28 to Sep 29
$193 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
8.6/10 Excellent! (2,620 reviews)
"Great historic property. Definitely has character. We enjoyed our stay. Clean, quiet and fairly centrally located for San Diego."

Reviewed on Sep 10, 2026

Opens in a new windowThe Sofia Hotel
Old Town Inn

Old Town Inn

2.5 out of 5
4444 Pacific Hwy San Diego CA
$155 nightly
The price is $178 total per night from Sep 15 to Sep 16
$178 total
Sep 15 - Sep 16
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Mission Bay and Port of San Diego are located nearby.
9/10 Wonderful! (1,977 reviews)
"Great place to stay if your there for your Marine graduate out of MCRD. It's only a two minute drive. Old Town isn't much further and is a great place to visit and dine at."

Reviewed on Sep 9, 2026

Opens in a new windowOld Town Inn
Humphreys Half Moon Inn

Humphreys Half Moon Inn

3.5 out of 5
2303 Shelter Island Dr San Diego CA
$211 nightly
The price is $243 total per night from Oct 4 to Oct 5
$243 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy a marina, a nightclub, and breakfast (surcharge). Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and Hotel del Coronado are located nearby.
Opens in a new windowHumphreys Half Moon Inn
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
$126 nightly
The price is $145 total per night from Oct 5 to Oct 6
$145 total
Oct 5 - Oct 6
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.
8.4/10 Very Good! (2,914 reviews)
"Amazing service and nice"

Reviewed on Sep 10, 2026

Opens in a new windowHandlery Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Picks

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.