Best Flight From Tampa Intl. To SAN

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Amazing TPA to SAN Flight Deals

The cheapest flights to San Diego Intl. were $250 for round trip flights and $126 for one-way flights in the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Sep 29 - Sat, Oct 3
TPA
Tampa
SAN
San Diego
$250 Roundtrip, found 1 day ago
$250
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, Sep 29 from Tampa to San Diego, returning Sat, Oct 3, priced at $250 found 1 day ago
Sun, Oct 4 - Thu, Oct 15
TPA
Tampa
SAN
San Diego
$252 Roundtrip, found 1 day ago
$252
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Oct 4 from Tampa to San Diego, returning Thu, Oct 15, priced at $252 found 1 day ago
Thu, Sep 10 - Tue, Sep 15
TPA
Tampa
SAN
San Diego
$266 Roundtrip, found 5 days ago
$266
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Thu, Sep 10 from Tampa to San Diego, returning Tue, Sep 15, priced at $266 found 5 days ago
Sat, Sep 5 - Tue, Sep 8
TPA
Tampa
SAN
San Diego
$271 Roundtrip, found 3 days ago
$271
Roundtrip
found 3 days ago
Select Alaska Airlines flight, departing Sat, Sep 5 from Tampa to San Diego, returning Tue, Sep 8, priced at $271 found 3 days ago
Sat, Sep 5 - Tue, Sep 8
TPA
Tampa
SAN
San Diego
$281 Roundtrip, found 3 days ago
$281
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sat, Sep 5 from Tampa to San Diego, returning Tue, Sep 8, priced at $281 found 3 days ago
Tue, Oct 20 - Tue, Oct 27
TPA
Tampa
SAN
San Diego
$288 Roundtrip, found 11 hours ago
$288
Roundtrip
found 11 hours ago
Select Bargain Flight flight, departing Tue, Oct 20 from Tampa to San Diego, returning Tue, Oct 27, priced at $288 found 11 hours ago

Hotels near San Diego Intl. Airport (SAN)

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$169 nightly
The price is $194 total per night from Aug 23 to Aug 24
$194 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
Opens in a new windowSheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Aug 17 to Aug 18
$211 total
Aug 17 - Aug 18
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
8.4/10 Very Good! (6,257 reviews)
"Friendly, excellent service!!!"

Reviewed on Aug 6, 2026

Opens in a new windowWyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$238 nightly
The price is $276 total per night from Sep 6 to Sep 7
$276 total
Sep 6 - Sep 7
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the helpful staff in our reviews. Popular attractions USS Midway Museum and Port of San Diego are located nearby.
9/10 Wonderful! (2,770 reviews)
"I enjoyed my stay and would happily return if I’m in the area."

Reviewed on Aug 6, 2026

Opens in a new windowManchester Grand Hyatt San Diego
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Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
$198 nightly
The price is $228 total per night from Sep 1 to Sep 2
$228 total
Sep 1 - Sep 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in our reviews. Popular attractions USS Midway Museum and Port of San Diego are located nearby.
9.2/10 Wonderful! (3,813 reviews)
"Shelter Island much preferred location for its quiet area, good walking paths, & Bay views."

Reviewed on Aug 6, 2026

Opens in a new windowBay Club Hotel & Marina
Homewood Suites by Hilton San Diego Airport/Liberty Station

Homewood Suites by Hilton San Diego Airport/Liberty Station

3 out of 5
2576 Laning Rd San Diego CA
$229 nightly
The price is $263 total per night from Sep 2 to Sep 3
$263 total
Sep 2 - Sep 3
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions USS Midway Museum and Port of San Diego are located nearby.
Opens in a new windowHomewood Suites by Hilton San Diego Airport/Liberty Station
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

3 out of 5
3737 Sports Arena Blvd San Diego CA
$125 nightly
The price is $144 total per night from Aug 30 to Aug 31
$144 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy parking (surcharge), a 24-hour front desk, and a business center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Bay and Mission Beach are located nearby.
7.4/10 Good! (4,168 reviews)
"Found another hotel first was placed in a handicap room the shower water ran all over the bathroom floor. I found not one but two roaches told the front deck they moved us to the second floor as to speak to the manager three times left messages he ducked me everytime the only good thing is the location ..."

Reviewed on Aug 6, 2026

Opens in a new windowWyndham Garden San Diego Near SeaWorld
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
$144 nightly
The price is $167 total per night from Aug 23 to Aug 24
$167 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
8.8/10 Excellent! (1,972 reviews)
"Breakfast is not included, as I thought when I booked the room. $20.00 per person. After I had fixed my plate, the nice little lady informed me. Too late to just leave the fixed plate. Never AGAIN!!!!"

Reviewed on Aug 6, 2026

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4 out of 5
1646 Front St San Diego CA
$179 nightly
The price is $208 total per night from Aug 24 to Aug 25
$208 total
Aug 24 - Aug 25
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
Opens in a new windowCourtyard by Marriott San Diego Downtown Little Italy
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.