Cheap flights from St. Louis (STL) to Panama City (PNS)

Get more for your budget and save up to 50% off select Secret Bargain hotels

Get even more value with CheapTickets Price Guarantee!

Change your flight without a fee on select flights

Lowest round trip fares by airline from St. Louis and Panama City

Cheapest prices ($40 One Way, $79 Round Trip) found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Great Deals On Cheap Hotels in Panama City

Boardwalk Beach Hotel

Boardwalk Beach Hotel

2.5 out of 5
9600 S Thomas Dr, Panama City Beach, FL
The price is $54 per night from Dec 1 to Dec 1
Nestled on the beach, this Panama City Beach hotel is within 1 mi (2 km) of Signal Hill Country Club and Thomas Drive. Ripley's Believe It or Not and WonderWorks ...
2.8/5 (13 reviews)
"There was not one things to like at this property. I paid over $1,200 for 5 nights and I had mold in the bathroom, no exhaust fan in the bathroom, no light on the balcony and my own swimming pool on the balcony because they did not have the pipes hooked up for drainage. The pipes laid underneath ..."

Reviewed on Jul 28, 2021

Boardwalk Beach Hotel
Casa Loma Inn

Casa Loma Inn

2 out of 5
13615 Front Beach Rd, Panama City Beach, FL
The price is $58 per night from Dec 9 to Dec 9
Nestled on the beach, this Bahama Beach motel is within 3 mi (5 km) of Hidden Lagoon Golf and Racetrack, Pier Park, and Shipwreck Island Waterpark. Thomas Drive ...
4.3/5 Excellent! (7 reviews)
"Great location. Older property, but well kept and clean."

Reviewed on Jul 16, 2020

Casa Loma Inn
Ramada by Wyndham Panama City Beach / Beachfront

Ramada by Wyndham Panama City Beach / Beachfront

2 out of 5
15405 Front Beach Rd., Panama City Beach, FL
The price is $89 per night from Dec 1 to Dec 1
Nestled on the beach, this Panama City Beach hotel is within 1 mi (2 km) of Russell-Fields Pier and Pier Park. Frank Brown Park and Shipwreck Island Waterpark ...
2/5 (9 reviews)
"We enjoyed the stay. The room was nice but it could use some updates in the rooms. We loved how we had a bocolny in the room. Overall it was nice. We enjoyed it."

Reviewed on Mar 20, 2021

Ramada by Wyndham Panama City Beach / Beachfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fly From St. Louis to Panama City

Origin St. Louis
Destination Panama City
Number of Daily Flights
Earliest Flight Departure Date
Latest Flight Departure Date
Popular Airlines

St. Louis to Panama City

Cheap flights from St. Louis to Panama City

Sign up for CheapTickets Deals E-mail, so you'll receive late-breaking alerts about airfare sales on cheap flights from St. Louis to Panama City.

Earn miles, choose seats on cheap flights from St. Louis to Panama City

Add your frequent flier numbers when you book your cheap flights from St. Louis to Panama City on CheapTickets and accumulate miles on applicable flights. Also, use our interactive maps to select your seats on flights from St. Louis to Panama City — aisle or window, front or back. We're not just concerned about finding you cheap flights from St. Louis to Panama City, we want to ensure you get your airline miles and preferred seats too.

An entire support team for your St. Louis to Panama City flights

When you book your St. Louis to Panama City flights on CheapTickets, you get free, real-time trip updates on your mobile phone. CheapTickets has a staff of air traffic analysts and travel experts monitoring events that could delay your St. Louis to Panama City flights. Choose to have your alerts sent to up to six others, like the person picking you up at the Panama City airport.

Need to change your cheap flights from St. Louis to Panama City?

Change your cheap flights from St. Louis to Panama City online with CheapTickets. No phone calls, no waiting. We'll let you know if there's part of your airfare that can be put toward a future flights from St. Louis to Panama City. Travel should be a pleasure, so that's why we strive to get you the best deal on cheap flights from St. Louis to Panama City and provide the travel support you deserve.

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.