Compare Cheap Hotels in Matlacha Isles Florida
Secret Bargains - Save an extra 10% or more on select hotels
Get more for your budget and save up to 50% off select Secret Bargain hotels
Get even more value with CheapTickets Price Guarantee!
Change your flight without a fee on select flights
Cheap Matlacha Isles Hotels

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E Cape Coral FL
$101 nightly
The price is $113 total per night
$113 total
Apr 5 - Apr 6
Total with taxes and fees
Free Cancellation
8.46 mi from Matlacha Isles
With a stay at Holiday Inn Express Cape Coral-Fort Myers Area by IHG in Cape Coral (Caloosahatchee), you'll be within a 10-minute walk of Hospital del Prado and Dolphin Marina.
Pool
Breakfast included

Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
$674 nightly
The price is $752 total per night
$752 total
Apr 6 - Apr 7
Total with taxes and fees
14.3 mi from Matlacha Isles
With a stay at Margaritaville Beach Resort Fort Myers in Fort Myers Beach, you'll be on the beach, within a 5-minute drive of Key West Express and Crescent Beach Family Park.
Pool
Spa

Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
$394 nightly
The price is $436 total per night
$436 total
Apr 12 - Apr 13
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
14.12 mi from Matlacha Isles
With a stay at Sanibel Island Beach Resort in Sanibel (Mid Island), you'll be a 1-minute drive from Sanibel Island Southern Beach and 6 minutes from Sanibel Island Lighthouse.

Baymont by Wyndham Fort Myers Central
4850 S Cleveland Ave Fort Myers FL
$85 nightly
The price is $95 total per night
$95 total
Apr 1 - Apr 2
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
11.54 mi from Matlacha Isles
In the heart of Fort Myers, Baymont by Wyndham Fort Myers Central is within a 5-minute drive of Bell Tower Shops and Fort Myers Country Club.
Pool
Breakfast included

Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
$319 nightly
The price is $356 total per night
$356 total
Apr 5 - Apr 6
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
14.42 mi from Matlacha Isles
With a stay at Lani Kai Beachfront Resort in Fort Myers Beach, you'll be on the beach, within a 5-minute drive of Key West Express and Estero Boulevard Beach.
Pool
Free WiFi

Hilton Garden Inn Ft Myers
12600 University Dr Fort Myers FL
$127 nightly
The price is $142 total per night
$142 total
Apr 12 - Apr 13
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
11.72 mi from Matlacha Isles
A stay at Hilton Garden Inn Ft Myers places you in the heart of Fort Myers, within a 5-minute drive of Barbara B Mann Hall and Bell Tower Shops.
Pool
Hot Tub

Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
$379 nightly
The price is $423 total per night
$423 total
Apr 1 - Apr 2
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
10.68 mi from Matlacha Isles
With a stay at Marriott Sanibel Harbour Resort & Spa in Fort Myers (Punta Rassa), you'll be within a 15-minute drive of Key West Express and Sanibel Island Southern Beach.
Pool
Hot Tub

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
11171 Summerlin Square Drive Fort Myers Beach FL
$121 nightly
The price is $135 total per night
$135 total
Apr 5 - Apr 6
Total with taxes and fees
12.36 mi from Matlacha Isles
With a stay at Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG in Fort Myers Beach, you'll be within a 10-minute drive of Key West Express and FastTrax Fort Myers.

Hyatt Place Fort Myers/at The Forum
2600 Champion Ring Rd Fort Myers FL
$189 nightly
The price is $211 total per night
$211 total
Mar 29 - Mar 30
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
15.35 mi from Matlacha Isles
Located in Fort Myers (The Forum), Hyatt Place Fort Myers/at The Forum is within a 10-minute drive of IMAG History & Science Center and Centennial Park.

DiamondHead Beach Resort
2000 Estero Blvd Fort Myers Beach FL
$464 nightly
The price is $517 total per night
$517 total
Apr 12 - Apr 13
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
14.61 mi from Matlacha Isles
With a stay at DiamondHead Beach Resort in Fort Myers Beach, you'll be on the beach, just steps from Estero Boulevard Beach and a 5-minute drive from Key West Express.

Courtyard by Marriott Fort Myers Cape Coral
4455 Metro Pkwy Fort Myers FL
$98 nightly
The price is $109 total per night
$109 total
Apr 5 - Apr 6
Total with taxes and fees
12.68 mi from Matlacha Isles
Located in Fort Myers, Courtyard by Marriott Fort Myers Cape Coral is a 3-minute drive from Edison Mall and 7 minutes from Edison and Ford Winter Estates.

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
10150 Daniels Pkwy Fort Myers FL
$99 nightly
The price is $110 total per night
$110 total
Mar 29 - Mar 30
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
17.36 mi from Matlacha Isles
With a stay at Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park in Fort Myers (Daniels Corridor), you'll be within a 15-minute drive of JetBlue Park at Fenway South and Florida Gulf Coast University.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Matlacha Isles hotels essential information
Accommodation | 14,621 hotels |
|---|---|
Lowest Price | $95 |
Highest Price | $752 |
Popular hotels | Holiday Inn Express Cape Coral-Fort Myers Area by IHG, Margaritaville Beach Resort Fort Myers , Sanibel Island Beach Resort, Baymont by Wyndham Fort Myers Central, Lani Kai Beachfront Resort, Hilton Garden Inn Ft Myers, Marriott Sanibel Harbour Resort & Spa, Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG, Hyatt Place Fort Myers/at The Forum, DiamondHead Beach Resort, Courtyard by Marriott Fort Myers Cape Coral, Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park |
Most Recent Matlacha Isles Hotel Reviews

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
5 out of 5
Posted 1 hour ago
CheapTickets Verified Review
"Great location, clean rooms, wonderful basic breakfast and coffee, I will be back again."
A verified traveler stayed at Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Top Picks
- Hotels with a Gym in Cape Coral
- Motel 6 Hotels in Bokeelia
- Cabin Rentals in Bokeelia
- Moody River Estates Hotels
- Chalets in Pine Island
- Extended Stay Hotels in North Fort Myers
- Gulf Shores Hotels
- Shell Point Hotels
- 5 Star Hotels in Saint James City
- Hotels with Kitchenettes in Cape Coral
- Matlacha Hotels
- Condo Resorts in Bokeelia
- Beach Resorts & in Cape Coral
- Hotels with a Wedding Venue in Cape Coral
- Fishing Resorts & in Pine Island
- Kid Friendly Hotels in Pine Island
- Beach Resorts & in North Captiva
- Romantic Getaways & Hotels in Matlacha
- Bokeelia Hotels
- Hotels near Goodwins Island
- Fort Myers Hotels
- Fishing Resorts & in Saint James City
- Iona Hotels
- Riverbend Country Club Hotels
- Sanibel Hotels
- Hotels with WiFi in North Fort Myers
- Chalets in North Fort Myers
- Kid Friendly Hotels in Cape Coral
- Villas in Pine Island
- Hotels near Sun Splash Water Park
- Kid Friendly Hotels in Matlacha
- 4 Star Hotels in North Fort Myers
- Oceanfront Hotels in Cape Coral
- Business Hotels in Cape Coral
- Boutique Hotels in Cape Coral
- Hotels near Key West Express
- Hotels near Causeway Islands Beach
- Pet Friendly Hotels in Cape Coral
- Motels in Bokeelia
- 5 Star Hotels in North Captiva
- Arcade Hotels in Cape Coral
- Condo Rentals in Matlacha
- Fishing Resorts & in Cape Coral
- 3 Star Hotels in Cape Coral
- Diplomat Hotels
- Historic Hotels in Pine Island
- Hotels with Free Parking in Matlacha
- Adventure Sport Hotels in Matlacha
- Tp Hill's Hotels
- Eight Lakes Hotels
- Hotels with Kitchenettes in Matlacha
- Hotels with Bars in Cape Coral
- Safety Harbor Club Hotels
- Hotels on the River in Cape Coral
- Cabin Rentals in Pine Island
- Hotels near Sanibel Island Lighthouse
- Town Houses in Bokeelia
- Harlem Heights Hotels
- Cape Harbour Hotels
- 4 Star Hotels in Pine Island
- Punta Rassa Hotels
- Casino Resorts & in Cape Coral
- Caloosahatchee Hotels
- Sabal Springs Hotels
- Ski Resorts & in Matlacha
- Hotels with Hot Tubs in Cape Coral
- Hotels with Balconies in Cape Coral
- Hotels with Balconies in Matlacha
- Pet Friendly Hotels in Matlacha
- Fort Myers Beach Hotels
- Dean Park Historic District Hotels
- Spa Resorts & in Cape Coral
- Flights from Omaha to Fort Myers
- Flights from Ottawa to Fort Myers
- Flights from Atlanta to Fort Myers
- Flights from Bakersfield to Fort Myers
- Flights from Santa Barbara to Fort Myers
- Flights to Saint James City
- Flights from Bentonville - Fayetteville to Fort Myers
- Flights to Cape Coral
- Flights from Kansas City to Fort Myers
- Flights from Fort Wayne to Fort Myers
- Flights from Greensboro to Fort Myers
- Flights from Providence to Fort Myers
- Flights from Evansville to Fort Myers
- Flights from Knoxville to Fort Myers
- Flights from Fort Myers
- Flights to Fort Myers
- Flights from Shreveport to Fort Myers
- Flights from Sacramento to Fort Myers
- Flights from Newark to Fort Myers





