Compare Cheap Hotels in Matlacha Isles Florida
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Cheap Matlacha Isles Hotels

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E Cape Coral FL
$95 nightly
The price is $106 total per night
$106 total
Dec 7 - Dec 8
Total with taxes and fees
Free Cancellation
8.45 mi from Matlacha Isles
With a stay at Holiday Inn Express Cape Coral-Fort Myers Area by IHG in Cape Coral (Caloosahatchee), you'll be within a 15-minute drive of Edison Mall and Hospital del Prado.
Pool
Breakfast included

Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
$244 nightly
The price is $272 total per night
$272 total
Dec 10 - Dec 11
Total with taxes and fees
14.3 mi from Matlacha Isles
With a stay at Margaritaville Beach Resort Fort Myers in Fort Myers Beach, you'll be on the beach, within a 5-minute drive of Key West Express and Crescent Beach Family Park.
Pool
Spa

Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
$164 nightly
The price is $182 total per night
$182 total
Dec 7 - Dec 8
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
14.42 mi from Matlacha Isles
With a stay at Lani Kai Beachfront Resort in Fort Myers Beach, you'll be on the beach, within a 5-minute drive of Key West Express and Estero Boulevard Beach.
Pool
Free WiFi

Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
$243 nightly
The price is $268 total per night
$268 total
Dec 15 - Dec 16
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
14.12 mi from Matlacha Isles
With a stay at Sanibel Island Beach Resort in Sanibel (Mid Island), you'll be a 5-minute walk from Sanibel Island Southern Beach and 7 minutes by foot from Sanibel Island Golf Club.
Pool
Pet friendly

DiamondHead Beach Resort
2000 Estero Blvd Fort Myers Beach FL
$244 nightly
The price is $272 total per night
$272 total
Dec 7 - Dec 8
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
14.61 mi from Matlacha Isles
With a stay at DiamondHead Beach Resort in Fort Myers Beach, you'll be on the beach, just steps from Estero Boulevard Beach and a 5-minute drive from Key West Express.
Pool
Hot Tub

Baymont by Wyndham Fort Myers Central
4850 S Cleveland Ave Fort Myers FL
$63 nightly
The price is $70 total per night
$70 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
11.54 mi from Matlacha Isles
In the heart of Fort Myers, Baymont by Wyndham Fort Myers Central is within a 5-minute drive of Bell Tower Shops and Fort Myers Country Club.
Pool
Breakfast included

Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
$231 nightly
The price is $258 total per night
$258 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
10.68 mi from Matlacha Isles
With a stay at Marriott Sanibel Harbour Resort & Spa in Fort Myers (Punta Rassa), you'll be within a 15-minute drive of Key West Express and Sanibel Island Southern Beach.
Pool
Hot Tub

Courtyard by Marriott Fort Myers Cape Coral
4455 Metro Pkwy Fort Myers FL
$89 nightly
The price is $99 total per night
$99 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
12.68 mi from Matlacha Isles
Located in Fort Myers, Courtyard by Marriott Fort Myers Cape Coral is a 3-minute drive from Edison Mall and 7 minutes from Edison and Ford Winter Estates.
Pool
Pet friendly

Sundial Beach Resort & Spa
1451 Middle Gulf Drive Sanibel FL
$408 nightly
The price is $455 total per night
$455 total
Dec 7 - Dec 8
Total with taxes and fees
14.37 mi from Matlacha Isles
With a stay at Sundial Beach Resort & Spa in Sanibel (Mid Island), you'll be a 4-minute drive from J. N. Ding Darling National Wildlife Refuge and 6 minutes from Dunes Golf and Tennis Club.
Pool
Hot Tub

Pink Shell Beach Resort and Marina
275 Estero Blvd Fort Myers Beach FL
$283 nightly
The price is $316 total per night
$316 total
Dec 7 - Dec 8
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
13.46 mi from Matlacha Isles
With a stay at Pink Shell Beach Resort and Marina in Fort Myers Beach, you'll be on the beach, just a 5-minute walk from Lynn Hall Memorial Park and a 2-minute drive from Estero Boulevard Beach.
Pool
Hot Tub

Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG
3427 Forum Blvd Fort Myers FL
$87 nightly
The price is $97 total per night
$97 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
15.82 mi from Matlacha Isles
With a stay at Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG in Fort Myers (The Forum), you'll be within a 10-minute drive of Edison Mall and JetBlue Park at Fenway South.
Pool
Breakfast included

Doubletree by Hilton Fort Myers at Bell Tower Shops
13051 Bell Tower Drive Fort Myers FL
$112 nightly
The price is $125 total per night
$125 total
Dec 15 - Dec 16
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
12.8 mi from Matlacha Isles
With a stay at Doubletree by Hilton Fort Myers at Bell Tower Shops in Fort Myers (Villas), you'll be steps from Bell Tower Shops and a 3-minute drive from Florida Southwestern State College.
Pool
Free airport shuttle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Matlacha Isles hotels essential information
Accommodation | 14,331 hotels |
|---|---|
Lowest Price | $70 |
Highest Price | $455 |
Popular hotels | Holiday Inn Express Cape Coral-Fort Myers Area by IHG, Margaritaville Beach Resort Fort Myers , Lani Kai Beachfront Resort, Sanibel Island Beach Resort, DiamondHead Beach Resort, Baymont by Wyndham Fort Myers Central, Marriott Sanibel Harbour Resort & Spa, Courtyard by Marriott Fort Myers Cape Coral, Sundial Beach Resort & Spa, Pink Shell Beach Resort and Marina, Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG, Doubletree by Hilton Fort Myers at Bell Tower Shops |
Most Recent Matlacha Isles Hotel Reviews

Pink Shell Beach Resort and Marina
5 out of 5
Posted 10 hours ago
CheapTickets Verified Review
"Great"
A verified traveler stayed at Pink Shell Beach Resort and Marina
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