Compare Business Hotels in Mexico and Central America
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Featured Mexico and Central America Business Hotels
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
$122 nightly
The price is $135 total per night
$135 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Centrally located in Panama City, Hotel Riu Plaza Panama is within a 15-minute walk of Crown Casino and Fiesta Casino.
Pool
Breakfast included
Galeria Plaza Reforma
Mexico City CDMX
$128 nightly
The price is $154 total per night
$154 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Galeria Plaza Reforma, you'll be centrally located in Mexico City, within a 10-minute walk of Angel of Independence Monument and U.S. Embassy.
Pool
Free WiFi
InterContinental Presidente Mexico City by IHG
Campos Eliseos 218 Mexico City
$239 nightly
The price is $285 total per night
$285 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at InterContinental Presidente Mexico City by IHG, you'll be centrally located in Mexico City, just a 3-minute walk from Avenida Presidente Masaryk and 8 minutes by foot from Paseo de la Reforma.
Spa
Pet friendly
Sheraton Maria Isabel Mexico City Reforma
Paseo de la Reforma 325 Mexico City CDMX
$157 nightly
The price is $187 total per night
$187 total
Jan 25 - Jan 26, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Sheraton Maria Isabel Mexico City Reforma, you'll be centrally located in Mexico City, steps from U.S. Embassy and within a 5-minute walk of Angel of Independence Monument.
Pool
Spa
Hyatt Regency Mexico City
Campos Eliseos No. 204 Polanco Mexico City
$227 nightly
The price is $271 total per night
$271 total
Jan 17 - Jan 18, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Mexico City (Polanco), Hyatt Regency Mexico City is within a 10-minute walk of Paseo de la Reforma and Auditorio Nacional.
Pool
Spa
Barceló Guatemala City
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
$82 nightly
The price is $100 total per night
$100 total
Jan 25 - Jan 26, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Guatemala City (Zona 9), Barceló Guatemala City is within a 5-minute drive of Natural History Museum and Oakland Mall.
Pool
Hot Tub
Camino Real Aeropuerto Mexico
Mexico City
$118 nightly
The price is $141 total per night
$141 total
Jan 29 - Jan 30, 2026
Total with taxes and fees
Free Cancellation
Located in Mexico City (Venustiano Carranza), Camino Real Aeropuerto Mexico is within a 10-minute drive of Sports Palace Dome and GNP Seguros Stadium.
Pool
Spa
Barceló México Reforma
Paseo De La Reforma 1 Mexico City
$112 nightly
The price is $133 total per night
$133 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Barceló México Reforma, you'll be centrally located in Mexico City, a 8-minute walk from Teatro Metropólitan and 14 minutes by foot from Palacio de Bellas Artes.
Pool
Hot Tub
Novotel Panama City
Calle Jose I. Fabrega y Thais de Pons Panama City Panama
$109 nightly
The price is $120 total per night
$120 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Novotel Panama City in Panama City (Bella Vista), you'll be within a 5-minute drive of Via Espana and Multiplaza Pacific Mall.
Parking included
Free WiFi
Hotel Riu Plaza Guadalajara
Av. Lopez Mateos 830 Col. Chapalita Guadalajara JAL
$113 nightly
The price is $137 total per night
$137 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Hotel Riu Plaza Guadalajara places you in the heart of Guadalajara, within a 5-minute drive of Expo Guadalajara and World Trade Center.
Pool
Free WiFi
Barceló San José
Autopista General Canas 3km San José San Jose
$84 nightly
The price is $95 total per night
$95 total
Jan 25 - Jan 26, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
In the heart of San José, Barceló San José is within a 5-minute drive of Sabana Park and National Stadium of Costa Rica.
Pool
Spa
Hotel Novit
Mexico City
$107 nightly
The price is $128 total per night
$128 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Hotel Novit in Mexico City (Benito Juarez), you'll be a 1-minute drive from World Trade Center Mexico City and 5 minutes from Angel of Independence Monument.
Pool
Free WiFi
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See all available properties in Mexico and Central America
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mexico and Central America Business Hotels essential information
Business Hotels in Mexico and Central America |
4205 |
|---|---|
Highest price | $285 |
Cheapest price | $95 |
Total number of hotels in Mexico and Central America | 103,867 |
Popular hotels | Hotel Riu Plaza Panama, Galeria Plaza Reforma, InterContinental Presidente Mexico City by IHG, Sheraton Maria Isabel Mexico City Reforma, Hyatt Regency Mexico City, Barceló Guatemala City, Camino Real Aeropuerto Mexico, Barceló México Reforma, Novotel Panama City, Hotel Riu Plaza Guadalajara, Barceló San José, Hotel Novit |
Most Recent Mexico and Central America Hotel Reviews
Hotel Riu Palace Las Americas - Adults Only- All Inclusive
5 out of 5
Posted 9 hours ago
CheapTickets Verified Review
"Clean everything, all staff very good and happy, great Xmas eve. Nice Art Deco bar and bar tender. Great coffee bar and staff"
A verified traveler stayed at Hotel Riu Palace Las Americas - Adults Only- All Inclusive
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