Compare Business Hotels in Mexico and Central America

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Featured Mexico and Central America Business Hotels

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
$114 nightly
The price is $126 total per night
$126 total
Dec 8 - Dec 9
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Centrally located in Panama City, Hotel Riu Plaza Panama is within a 15-minute walk of Crown Casino and Fiesta Casino.
Pool
Breakfast included
Galeria Plaza Reforma

Galeria Plaza Reforma

4 out of 5
Mexico City CDMX
$156 nightly
The price is $186 total per night
$186 total
Dec 17 - Dec 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Galeria Plaza Reforma, you'll be centrally located in Mexico City, within a 10-minute walk of Angel of Independence Monument and U.S. Embassy.
Pool
Free WiFi
InterContinental Presidente Mexico City by IHG

InterContinental Presidente Mexico City by IHG

4 out of 5
Campos Eliseos 218 Mexico City
$251 nightly
The price is $300 total per night
$300 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at InterContinental Presidente Mexico City by IHG places you in the heart of Mexico City, within a 10-minute walk of Paseo de la Reforma and Auditorio Nacional.
Spa
Pet friendly
Sheraton Maria Isabel Mexico City Reforma

Sheraton Maria Isabel Mexico City Reforma

4 out of 5
Paseo de la Reforma 325 Mexico City CDMX
$149 nightly
The price is $178 total per night
$178 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Sheraton Maria Isabel Mexico City Reforma, you'll be centrally located in Mexico City, steps from U.S. Embassy and within a 5-minute walk of Angel of Independence Monument.
Pool
Spa
Hyatt Regency Mexico City

Hyatt Regency Mexico City

5 out of 5
Campos Eliseos No. 204 Polanco Mexico City
$234 nightly
The price is $279 total per night
$279 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Mexico City (Polanco), Hyatt Regency Mexico City is within a 10-minute walk of Paseo de la Reforma and Auditorio Nacional.
Pool
Spa
Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
$66 nightly
The price is $81 total per night
$81 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Guatemala City (Zona 9), Barceló Guatemala City is within a 5-minute drive of Natural History Museum and Oakland Mall.
Pool
Hot Tub
Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

4 out of 5
Mexico City
$132 nightly
The price is $158 total per night
$158 total
Dec 29 - Dec 30
Total with taxes and fees
Free Cancellation
Located in Mexico City (Venustiano Carranza), Camino Real Aeropuerto Mexico is within a 10-minute drive of Sports Palace Dome and GNP Seguros Stadium.
Pool
Spa
Barceló México Reforma

Barceló México Reforma

4.5 out of 5
Paseo De La Reforma 1 Mexico City
$112 nightly
The price is $133 total per night
$133 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Barceló México Reforma, you'll be centrally located in Mexico City, a 8-minute walk from Teatro Metropólitan and 14 minutes by foot from Palacio de Bellas Artes.
Pool
Hot Tub
Novotel Panama City

Novotel Panama City

4 out of 5
Calle Jose I. Fabrega y Thais de Pons Panama City Panama
$96 nightly
The price is $106 total per night
$106 total
Dec 7 - Dec 8
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Novotel Panama City in Panama City (Bella Vista), you'll be within a 5-minute drive of Via Espana and Multiplaza Pacific Mall.
Parking included
Free WiFi
Hotel Riu Plaza Guadalajara

Hotel Riu Plaza Guadalajara

5 out of 5
Av. Lopez Mateos 830 Col. Chapalita Guadalajara JAL
$99 nightly
The price is $120 total per night
$120 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Hotel Riu Plaza Guadalajara places you in the heart of Guadalajara, within a 5-minute drive of Expo Guadalajara and World Trade Center.
Pool
Free WiFi
Barceló San José

Barceló San José

4 out of 5
Autopista General Canas 3km San José San Jose
$105 nightly
The price is $119 total per night
$119 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
In the heart of San José, Barceló San José is within a 5-minute drive of Sabana Park and National Stadium of Costa Rica.
Pool
Spa
Hotel Novit

Hotel Novit

4 out of 5
Mexico City
$107 nightly
The price is $128 total per night
$128 total
Dec 12 - Dec 13
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Hotel Novit in Mexico City (Benito Juarez), you'll be a 1-minute drive from World Trade Center Mexico City and 5 minutes from Angel of Independence Monument.
Pool
Free WiFi
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mexico and Central America Business Hotels essential information

 

Business Hotels in Mexico and Central America

4205

Highest price
$300
Cheapest price
$81
Total number of hotels in Mexico and Central America
104,010
Popular hotels
Hotel Riu Plaza Panama, Galeria Plaza Reforma, InterContinental Presidente Mexico City by IHG, Sheraton Maria Isabel Mexico City Reforma, Hyatt Regency Mexico City, Barceló Guatemala City, Camino Real Aeropuerto Mexico, Barceló México Reforma, Novotel Panama City, Hotel Riu Plaza Guadalajara, Barceló San José, Hotel Novit

 

Most Recent Mexico and Central America Hotel Reviews

Hotel Riu Palace Las Americas - Adults Only- All Inclusive

Hotel Riu Palace Las Americas - Adults Only- All Inclusive

5 out of 5
Posted 19 hours ago
CheapTickets Verified Review
"Just got back from Thanksgiving in Cancun! Had an amazing trip! This hotel is the cleanest all inclusive we have stayed at. We have been to Cancun over 10 times and loved it here! The beach is beautiful and the waves are not as rough so you can actually go in and swim! The staff is wonderful! All friendly and helpful! Shout out to the entertainment team! So fun with games and exercise classes! Samantha and Michel were awesome! Can not wait to return here! We are going back!"
A verified traveler stayed at Hotel Riu Palace Las Americas - Adults Only- All Inclusive
Hotel Riu Palace Las Americas - Adults Only- All Inclusive

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