Best Flight From Detroit Metropolitan Wayne County To SAN

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Amazing DTW to SAN Flight Deals

The cheapest flights to San Diego Intl. were $282 for round trip flights and $156 for one-way flights in the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Nov 10 - Tue, Nov 17
DTW
Detroit
SAN
San Diego
$282 Roundtrip, found 2 days ago
$282
Roundtrip
found 2 days ago
Select Bargain Flight flight, departing Tue, Nov 10 from Detroit to San Diego, returning Tue, Nov 17, priced at $282 found 2 days ago
Fri, Aug 14 - Sun, Aug 30
DTW
Detroit
SAN
San Diego
$289 Roundtrip, found 3 days ago
$289
Roundtrip
found 3 days ago
Select Bargain Flight flight, departing Fri, Aug 14 from Detroit to San Diego, returning Sun, Aug 30, priced at $289 found 3 days ago
Thu, Nov 19 - Mon, Nov 23
DTW
Detroit
SAN
San Diego
$300 Roundtrip, found 2 hours ago
$300
Roundtrip
found 2 hours ago
Select Bargain Flight flight, departing Thu, Nov 19 from Detroit to San Diego, returning Mon, Nov 23, priced at $300 found 2 hours ago
Tue, Nov 10 - Tue, Nov 17
DTW
Detroit
SAN
San Diego
$308 Roundtrip, found 2 days ago
$308
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Tue, Nov 10 from Detroit to San Diego, returning Tue, Nov 17, priced at $308 found 2 days ago
Tue, Nov 10 - Tue, Nov 17
DTW
Detroit
SAN
San Diego
$315 Roundtrip, found 2 days ago
$315
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Tue, Nov 10 from Detroit to San Diego, returning Tue, Nov 17, priced at $315 found 2 days ago
Wed, Jul 22 - Wed, Aug 5
DTW
Detroit
SAN
San Diego
$318 Roundtrip, found 13 hours ago
$318
Roundtrip
found 13 hours ago
Select Frontier Airlines flight, departing Wed, Jul 22 from Detroit to San Diego, returning Wed, Aug 5, priced at $318 found 13 hours ago

Hotels near San Diego Intl. Airport (SAN)

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$203 nightly
The price is $234 total per night from Jul 1 to Jul 2
$234 total
Jul 1 - Jul 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
8.4/10 Very Good! (3,542 reviews)
"Overall, we are satisfied. Front desk workers were polite and helpful and I can not understand why in other reviews there were a lot of negative comments. Parking was pricey, 55$ per night. We stayed 2 nights. There was an iron and a desk, as well as a coffee machine with coffee tablets provided, ..."

Reviewed on Jun 14, 2026

Opens in a new windowSheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Jun 16 to Jun 17
$211 total
Jun 16 - Jun 17
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
8.4/10 Very Good! (6,191 reviews)
"Check in took a little longer than expected as there was only one front desk clerk and a really long line. It wasn’t her fault as I heard her mention she asked for help but the manager brushed her off. The room was small but worked for us. The view of the bay was amazing and it was so neat"

Reviewed on Jun 13, 2026

Opens in a new windowWyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$296 nightly
The price is $343 total per night from Jul 1 to Jul 2
$343 total
Jul 1 - Jul 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. Popular attractions USS Midway Museum and Port of San Diego are located nearby.
9/10 Wonderful! (2,812 reviews)
"I love everything about this place For sure, I will come back again"

Reviewed on Jun 14, 2026

Opens in a new windowManchester Grand Hyatt San Diego
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The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
$143 nightly
The price is $166 total per night from Jun 15 to Jun 16
$166 total
Jun 15 - Jun 16
Total with taxes and fees
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
8.6/10 Excellent! (2,241 reviews)
"Was in town for a convention at the Convention Center which was only about a 1/2 mile / 10-15 minute walk away. Chipotle across the street was a lifesaver. Near the Balboa Theater if you’re in town to see a play/ show. Lots of restaurants in the Gaslight District. Petco Park next to Convention Center. ..."

Reviewed on Jun 14, 2026

Opens in a new windowThe Sofia Hotel
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
$179 nightly
The price is $206 total per night from Jun 15 to Jun 16
$206 total
Jun 15 - Jun 16
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in our reviews. Popular attractions USS Midway Museum and Port of San Diego are located nearby.
9.2/10 Wonderful! (3,660 reviews)
"The room smelled a bit musty and the sheets had stains on them. The fitness area was pretty small with old equipment. The only cardio machines were an elliptical and a bike that were both pretty old and not of real good quality. The fitness center is used by people who have boats at the marina which ..."

Reviewed on Jun 13, 2026

Opens in a new windowBay Club Hotel & Marina
The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld

2.5 out of 5
San Diego CA
$120 nightly
The price is $137 total per night from Jun 15 to Jun 16
$137 total
Jun 15 - Jun 16
Total with taxes and fees
Book a stay at this golf hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Bay and San Diego Zoo are located nearby.
8/10 Very Good! (212 reviews)
"The room was dirty"

Reviewed on Jun 13, 2026

Opens in a new windowThe Alcala Hotel Mission Valley/Seaworld
Homewood Suites by Hilton San Diego Airport/Liberty Station

Homewood Suites by Hilton San Diego Airport/Liberty Station

3 out of 5
2576 Laning Rd San Diego CA
$238 nightly
The price is $274 total per night from Jun 30 to Jul 1
$274 total
Jun 30 - Jul 1
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions USS Midway Museum and Port of San Diego are located nearby.
Opens in a new windowHomewood Suites by Hilton San Diego Airport/Liberty Station
Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG

3.5 out of 5
2270 Hotel Cir N San Diego CA
$129 nightly
The price is $149 total per night from Jun 29 to Jun 30
$149 total
Jun 29 - Jun 30
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions San Diego Zoo and Mission Bay are located nearby.
8.2/10 Very Good! (1,050 reviews)
"Everything was awesome n super friendly"

Reviewed on Jun 14, 2026

Opens in a new windowCrowne Plaza San Diego - Mission Valley by IHG
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.