Best Flight From Detroit Metropolitan Wayne County To SAN

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Amazing DTW to SAN Flight Deals

The cheapest flights to San Diego Intl. were $210 for round trip flights and $116 for one-way flights in the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Jun 1 - Thu, Jun 4
DTW
Detroit
SAN
San Diego
$210 Roundtrip, found 3 days ago
$210
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Mon, Jun 1 from Detroit to San Diego, returning Thu, Jun 4, priced at $210 found 3 days ago
Fri, Jun 5 - Tue, Jun 9
DTW
Detroit
SAN
San Diego
$215 Roundtrip, found 3 days ago
$215
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, Jun 5 from Detroit to San Diego, returning Tue, Jun 9, priced at $215 found 3 days ago
Mon, Jun 1 - Thu, Jun 4
DTW
Detroit
SAN
San Diego
$230 Roundtrip, found 3 days ago
$230
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Mon, Jun 1 from Detroit to San Diego, returning Thu, Jun 4, priced at $230 found 3 days ago
Thu, May 28 - Mon, Jun 1
DTW
Detroit
SAN
San Diego
$236 Roundtrip, found 1 day ago
$236
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, May 28 from Detroit to San Diego, returning Mon, Jun 1, priced at $236 found 1 day ago
Fri, Jul 10 - Sat, Aug 1
DTW
Detroit
SAN
San Diego
$244 Roundtrip, found 1 day ago
$244
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Jul 10 from Detroit to San Diego, returning Sat, Aug 1, priced at $244 found 1 day ago
Fri, Jul 10 - Sat, Aug 1
DTW
Detroit
SAN
San Diego
$250 Roundtrip, found 1 day ago
$250
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Jul 10 from Detroit to San Diego, returning Sat, Aug 1, priced at $250 found 1 day ago

Hotels near San Diego Intl. Airport (SAN)

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$169 nightly
The price is $194 total per night from May 3 to May 4
$194 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
8.4/10 Very Good! (3,498 reviews)
We stayed in the North Tower and were given a recently renovated room. Unfortunately, I was unable to sleep all night due to a loud banging noise occurring every few minutes. We later realized it seemed to be coming from the air conditioning compressor or related system, which made a very loud banging ...

Reviewed on Apr 27, 2026

Opens in a new windowSheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from May 3 to May 4
$211 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
8.4/10 Very Good! (6,125 reviews)
.

Reviewed on Apr 28, 2026

Opens in a new windowWyndham San Diego Bayside
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
$119 nightly
The price is $138 total per night from May 25 to May 26
$138 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
8.8/10 Excellent! (1,473 reviews)
The room was very clean, no bugs, room included an ice container and items for coffee as well as the bible. Plenty of drawer space. Restroom had plenty of counter space to do makeup and the room itself had lots of plug ins. The room felt very safe and secure as you had to have certain keys to get ...

Reviewed on Apr 28, 2026

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
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Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
$152 nightly
The price is $175 total per night from May 6 to May 7
$175 total
May 6 - May 7
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in our reviews. Popular attractions USS Midway Museum and Port of San Diego are located nearby.
9.2/10 Wonderful! (3,547 reviews)
The Bay Club is such a nice hotel so close to downtown San Diego, the airport, the beaches. It is the perfect location. I had a room overlooking the marina, it was so relaxing. I really enjoyed my stay for 14 nights. It was a business trip but it felt like being on vacation as well. I highly recommend ...

Reviewed on Apr 29, 2026

Opens in a new windowBay Club Hotel & Marina
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
$154 nightly
The price is $178 total per night from Apr 30 to May 1
$178 total
Apr 30 - May 1
Total with taxes and fees
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
8.6/10 Excellent! (1,967 reviews)
Great location nice room. Once their restaurant an bar are open it’s worth 5 stars.

Reviewed on Apr 29, 2026

Opens in a new windowThe Sofia Hotel
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$236 nightly
The price is $274 total per night from May 25 to May 26
$274 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. Popular attractions USS Midway Museum and Port of San Diego are located nearby.
9/10 Wonderful! (2,838 reviews)
The Manchester Hyatt always delivers as expected. They have valet and bellhop which is important to me traveling with a special needs child and I need the convenience of having some help moving all of the luggage up to the room and parking the car for us. The room was well appointed and clean. They ...

Reviewed on Apr 25, 2026

Opens in a new windowManchester Grand Hyatt San Diego
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

3 out of 5
3737 Sports Arena Blvd San Diego CA
$113 nightly
The price is $130 total per night from May 5 to May 6
$130 total
May 5 - May 6
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy parking (surcharge), a 24-hour front desk, and a business center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Bay and Mission Beach are located nearby.
7.4/10 Good! (4,212 reviews)
Nice place , good location

Reviewed on Apr 29, 2026

Opens in a new windowWyndham Garden San Diego Near SeaWorld
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

2.5 out of 5
2485 Hotel Circle Place San Diego CA
$116 nightly
The price is $133 total per night from May 10 to May 11
$133 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Mission Bay and San Diego Zoo are located nearby.
8/10 Very Good! (2,617 reviews)
Clean room and great customer service.

Reviewed on Apr 29, 2026

Opens in a new windowBest Western Inn & Suites San Diego – Zoo/SeaWorld Area
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Picks

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.