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Featured St. Charles Business Hotels

Home2 Suites by Hilton St. Charles St.Louis
32 Research Park Circle St. Charles MO
Located in St. Charles, Home2 Suites by Hilton St. Charles St.Louis is in the suburbs, a 1-minute drive from Missouri Bluffs Golf Course and 6 minutes from Weldon Spring Site Interpretive Center.

Best Western Plus The Charles Hotel
1425 South 5th Street St. Charles MO
When you stay at Best Western Plus The Charles Hotel in St. Charles, you'll be in the historical district, within a 5-minute drive of Ameristar Casino St. Charles and Hollywood Casino Amphitheatre.

Embassy Suites by Hilton St. Louis St. Charles
2 Convention Center Plz St. Charles MO
$130 nightly
The price is $150 total per night
$150 total
Apr 12 - Apr 13
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Embassy Suites by Hilton St. Louis St. Charles in St. Charles, you'll be connected to the convention center, within a 5-minute drive of Ameristar Casino St. Charles and Hollywood Casino Amphitheatre.

Country Inn & Suites by Radisson, St. Charles Historic District
1190 S Main St St. Charles MO
$135 nightly
The price is $155 total per night
$155 total
May 3 - May 4
Total with taxes and fees
Free Cancellation
With a stay at Country Inn & Suites by Radisson, St. Charles Historic District in St. Charles (St. Charles Historic District), you'll be a 1-minute drive from Ameristar Casino St. Charles and 6 minutes from Hollywood Casino Amphitheatre.

Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
$193 nightly
The price is $226 total per night
$226 total
Apr 7 - Apr 8
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Ameristar Casino Resort and Spa places you in the heart of St. Charles, steps from Ameristar Casino St. Charles and a 4-minute drive from Family Arena.

Hampton Inn St. Charles St. Peters
3720 W Clay St St. Charles MO
$106 nightly
The price is $122 total per night
$122 total
Apr 13 - Apr 14
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Hampton Inn St. Charles St. Peters in St. Charles, you'll be next to a golf course, within a 10-minute drive of Ameristar Casino St. Charles and Hollywood Casino Amphitheatre.
Red Roof Inn St Louis - St Charles
2010 Zumbehl Road St. Charles MO
With a stay at Red Roof Inn St Louis - St Charles in St. Charles, you'll be within a 10-minute drive of Ameristar Casino St. Charles and Hollywood Casino Amphitheatre.

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
1310 Bass Pro Drive St. Charles MO
$90 nightly
The price is $104 total per night
$104 total
Apr 7 - Apr 8
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in St. Charles, Americas Best Value Inn & Suites St. Louis, St. Charles Inn is in the historical district, within a 5-minute drive of First Missouri State Capitol Historic Site and Lindenwood University.

Comfort Suites St Charles - St Louis
1400 S 5th St St. Charles MO
$90 nightly
The price is $103 total per night
$103 total
May 3 - May 4
Total with taxes and fees
Free Cancellation
With a stay at Comfort Suites St Charles - St Louis, you'll be centrally located in St. Charles, a short 8-minute walk from Ameristar Casino St. Charles and 14 minutes by foot from Historic Main Street.

Holiday Inn Express Hotel and Suites St. Charles by IHG
3098 Elm Point Industrial Drive St. Charles MO
$127 nightly
The price is $146 total per night
$146 total
Apr 9 - Apr 10
Total with taxes and fees
Free Cancellation
When you stay at Holiday Inn Express Hotel and Suites St. Charles by IHG in St. Charles, you'll be in the historical district, within a 15-minute drive of Hollywood Casino Amphitheatre and Ameristar Casino St. Charles.

Drury Plaza Hotel St. Louis St. Charles
380 Mulholland Drive St. Charles MO
$132 nightly
The price is $153 total per night
$153 total
May 3 - May 4
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Drury Plaza Hotel St. Louis St. Charles in St. Charles, you'll be in the business district, within a 5-minute drive of Ameristar Casino St. Charles and Hollywood Casino Amphitheatre.

Sleep Inn Saint Charles North
150 Fountain Lakes Blvd St. Charles MO
$74 nightly
The price is $85 total per night
$85 total
Apr 26 - Apr 27
Total with taxes and fees
Free Cancellation
Located in St. Charles, Sleep Inn Saint Charles North is in the historical district, within a 10-minute drive of Fast Lane Classic Cars and Lindenwood University.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
St. Charles hotels essential information
Accommodation | 2,378 hotels |
|---|---|
Lowest Price | $85 |
Highest Price | $226 |
Popular hotels | Home2 Suites by Hilton St. Charles St.Louis, Best Western Plus The Charles Hotel, Embassy Suites by Hilton St. Louis St. Charles, Country Inn & Suites by Radisson, St. Charles Historic District, Ameristar Casino Resort and Spa, Hampton Inn St. Charles St. Peters, Red Roof Inn St Louis - St Charles, Americas Best Value Inn & Suites St. Louis, St. Charles Inn, Comfort Suites St Charles - St Louis, Holiday Inn Express Hotel and Suites St. Charles by IHG, Drury Plaza Hotel St. Louis St. Charles, Sleep Inn Saint Charles North |
Most Recent St. Charles Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch
4 out of 5
Posted 1 hour ago
CheapTickets Verified Review
"Staff was really nice and friendly and helpful! Depending on where you face it can be really loud bc of the highway. Windows aren’t soundproofed very well. Parking ranges from about $28-$30 a night, and some of the parking is off sight in a garage. We didn’t know this would happen, so we are lucky we didn’t have a luggage topper attached to our vehicle. Free breakfast, dinner and 3 cocktails per adult was a nice benefit to equal out the cost of parking.
The pool isn’t as big as you might think, so consider this when you have kids. If MO kids are on break it is BUSY and crowded.
I would have liked better housekeeping during our stay, but otherwise it was a good stay for the price. "
A verified traveler stayed at Drury Plaza Hotel St. Louis at the Arch
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