Compare Spa Resorts & Hotels in Panama City
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Featured Panama City Spa Resorts & Hotels
Bristol Panama, a Registry Collection Hotel
Avenida Aquilino de La Guardia Panama City Panama
$200 nightly
The price is $220 total per night
$220 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Bristol Panama, a Registry Collection Hotel, you'll be centrally located in Panama City, steps from Calle 50 and within a 10-minute walk of Soho City Center.
Pool
Spa
Decapolis Hotel Panama City
Avenida Balboa Con Multicentro Panama City Panama
$113 nightly
The price is $125 total per night
$125 total
Jan 8 - Jan 9, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Decapolis Hotel Panama City, you'll be centrally located in Panama City, steps from Avenida Balboa and Multicentro Panama.
Pool
Breakfast included
Megapolis Hotel Panamá
Ave. Balboa al lado de Multicentro, 63 Panama City Panamá Province
With a stay at Megapolis Hotel Panamá, you'll be centrally located in Panama City, steps from Multicentro Panama and Avenida Balboa.
Hot Tub
All inclusive
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
56 y 57 East Street, Obarrio Panama City Panama
$159 nightly
The price is $175 total per night
$175 total
Dec 13 - Dec 14
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Sortis Hotel, Spa & Casino, Autograph Collection by Marriott places you in the heart of Panama City, within a 15-minute walk of Via Espana and Avenida Balboa.
Pool
Spa
Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz Veracruz Panama
$272 nightly
The price is $272 total per night
$272 total
Dec 18 - Dec 19
Total with taxes and fees
When you stay at Dreams Playa Bonita Panama - All Inclusive in Veracruz, you'll be on the beach, within a 15-minute drive of Albrook Shopping Mall and Cinta Costera.
Pool
Breakfast included
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
$175 nightly
The price is $192 total per night
$192 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Las Americas Golden Tower Panama, you'll be centrally located in Panama City, a 4-minute walk from Multicentro Panama and a 2-minute drive from Fiesta Casino.
Pool
Spa
JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
$269 nightly
The price is $296 total per night
$296 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Centrally located in Panama City, JW Marriott Panama is within a 15-minute walk of Multiplaza Pacific Mall and Avenida Balboa.
Pool
Spa
Eurostars Panama City
Calle Ricardo Arias Panama City Panama
With a stay at Eurostars Panama City, you'll be centrally located in Panama City, steps from Via Espana and 13 minutes by foot from Avenida Balboa.
Pool
Hot Tub
The Westin Playa Bonita Panama
Km 6 Road to Veracruz Veracruz Panama
$199 nightly
The price is $219 total per night
$219 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Veracruz, The Westin Playa Bonita Panama is by the ocean, within a 15-minute drive of Interoceanic Canal Museum and Albrook Shopping Mall.
On private beach
Pool
Waymore Hotel Spa and Casino
Via Veneto Y Avenida Eusebio Morales Panama City Panamá Province
With a stay at Waymore Hotel Spa and Casino in Panama City (Bella Vista), you'll be a 3-minute walk from Via Espana and within a 5-minute drive of Albrook Shopping Mall.
Pool
Spa
Sheraton Grand Panama
Via Israel And 77th Street Panama City Panama
$134 nightly
The price is $148 total per night
$148 total
Jan 9 - Jan 10, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Sheraton Grand Panama in Panama City (San Francisco), you'll be within a 5-minute drive of Multiplaza Pacific Mall and Cinta Costera.
Pool
Spa
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
$122 nightly
The price is $135 total per night
$135 total
Dec 15 - Dec 16
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Centrally located in Panama City, Hotel Riu Plaza Panama is within a 15-minute walk of Crown Casino and Fiesta Casino.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Panama City hotels essential information
Accommodation | 1,633 hotels |
|---|---|
Lowest Price | $125 |
Highest Price | $296 |
Popular hotels | Bristol Panama, a Registry Collection Hotel, Decapolis Hotel Panama City, Megapolis Hotel Panamá, Sortis Hotel, Spa & Casino, Autograph Collection by Marriott, Dreams Playa Bonita Panama - All Inclusive, Las Americas Golden Tower Panama, JW Marriott Panama, Eurostars Panama City, The Westin Playa Bonita Panama, Waymore Hotel Spa and Casino, Sheraton Grand Panama, Hotel Riu Plaza Panama |
Most Recent Panama City Hotel Reviews
W Panama
5 out of 5
Posted 6 hours ago
CheapTickets Verified Review
"Staff was friendly, room service was timely! I travelled for my birthday and they helped make my day a little bit more special.
Didn’t get the full spa experience, but the massage was awesome. Can’t wait to visit again. "
A verified traveler stayed at W Panama
Types of Hotels
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