Compare Spa Resorts & Hotels in Panama
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Featured Panama Spa Resorts & Hotels

Bristol Panama, a Registry Collection Hotel
Avenida Aquilino de La Guardia Panama City Panama
$180 nightly
The price is $198 total per night
$198 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Bristol Panama, a Registry Collection Hotel, you'll be centrally located in Panama City, steps from Calle 50 and within a 10-minute walk of Soho City Center.
Pool
Spa

Decapolis Hotel Panama City
Avenida Balboa Con Multicentro Panama City Panama
$76 nightly
The price is $84 total per night
$84 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Decapolis Hotel Panama City, you'll be centrally located in Panama City, steps from Avenida Balboa and Multicentro Panama.
Pool
Breakfast included

Megapolis Hotel Panamá
Ave. Balboa al lado de Multicentro, 63 Panama City Panamá Province
With a stay at Megapolis Hotel Panamá, you'll be centrally located in Panama City, steps from Multicentro Panama and Avenida Balboa.
Hot Tub
All inclusive

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
56 y 57 East Street, Obarrio Panama City Panama
$159 nightly
The price is $175 total per night
$175 total
Dec 6 - Dec 7
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Sortis Hotel, Spa & Casino, Autograph Collection by Marriott places you in the heart of Panama City, within a 15-minute walk of Via Espana and Avenida Balboa.
Pool
Spa

Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz Veracruz Panama
$272 nightly
The price is $272 total per night
$272 total
Dec 18 - Dec 19
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Dreams Playa Bonita Panama - All Inclusive in Veracruz, you'll be on the beach, within a 15-minute drive of Albrook Shopping Mall and Cinta Costera.
Pool
Breakfast included

Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
$175 nightly
The price is $192 total per night
$192 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Las Americas Golden Tower Panama, you'll be centrally located in Panama City, a 4-minute walk from Multicentro Panama and a 2-minute drive from Fiesta Casino.
Pool
Spa

The Haven and Spa - Health and Wellness Accommodation - Adults Only
Avenida A Oeste, Bajo Boquete Chiriqui
When you stay at The Haven and Spa - Health and Wellness Accommodation - Adults Only in Boquete, you'll be in a national park, within a 5-minute drive of Boquete Library and Municipal Park.
Pool
Hot Tub

Los Mandarinos Hotel Boutique & Spa
Jv6j+m5 El Valle De Antón El Valle de Anton Coclé
When you stay at Los Mandarinos Hotel Boutique & Spa in El Valle de Anton, you'll be in the mountains, within a 5-minute drive of Square Trees Nature Trail and Anton Valley Historical and Cultural Museum.
Pool
Hot Tub

JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
$251 nightly
The price is $276 total per night
$276 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Centrally located in Panama City, JW Marriott Panama is within a 15-minute walk of Multiplaza Pacific Mall and Avenida Balboa.
Pool
Spa

Eurostars Panama City
Calle Ricardo Arias Panama City Panama
With a stay at Eurostars Panama City, you'll be centrally located in Panama City, steps from Via Espana and 13 minutes by foot from Avenida Balboa.
Pool
Hot Tub

The Westin Playa Bonita Panama
Km 6 Road to Veracruz Veracruz Panama
$166 nightly
The price is $183 total per night
$183 total
Dec 16 - Dec 17
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Veracruz, The Westin Playa Bonita Panama is by the ocean, within a 15-minute drive of Interoceanic Canal Museum and Albrook Shopping Mall.
On private beach
Pool
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Panama Spa Resorts & Hotels essential information
Spa Resorts & Hotels in Panama |
120 |
|---|---|
Highest price | $276 |
Cheapest price | $84 |
Total number of hotels in Panama | 3,556 |
Popular hotels | Bristol Panama, a Registry Collection Hotel, Decapolis Hotel Panama City, Megapolis Hotel Panamá, Sortis Hotel, Spa & Casino, Autograph Collection by Marriott, Dreams Playa Bonita Panama - All Inclusive, Las Americas Golden Tower Panama, The Haven and Spa - Health and Wellness Accommodation - Adults Only, Los Mandarinos Hotel Boutique & Spa, JW Marriott Panama, Eurostars Panama City, The Westin Playa Bonita Panama, Gran Evenia Bijao - All Inclusive |
Most Recent Panama Hotel Reviews

W Panama
5 out of 5
Posted 9 hours ago
CheapTickets Verified Review
"Clean, great staff, all our transportation was done with very courteous staff from the hotel "
A verified traveler stayed at W Panama
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