Compare Business Hotels in Panama City
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Featured Panama City Business Hotels

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
$122 nightly
The price is $135 total per night
$135 total
Dec 15 - Dec 16
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Centrally located in Panama City, Hotel Riu Plaza Panama is within a 15-minute walk of Crown Casino and Fiesta Casino.

Novotel Panama City
Calle Jose I. Fabrega y Thais de Pons Panama City Panama
$106 nightly
The price is $117 total per night
$117 total
Dec 13 - Dec 14
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Novotel Panama City in Panama City (Bella Vista), you'll be within a 5-minute drive of Via Espana and Multiplaza Pacific Mall.

Doubletree By Hilton Panama City El Carmen
Via Espana Ave. Federico Boyd Bel Panama City Panama Province
With a stay at Doubletree By Hilton Panama City El Carmen, you'll be centrally located in Panama City, a 8-minute walk from Avenida Balboa and 11 minutes by foot from Cinta Costera.
Pool
Parking included

Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall Panama City Panama
$93 nightly
The price is $102 total per night
$102 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
Located in Panama City (San Francisco), Courtyard by Marriott Panama Multiplaza Mall is within a 15-minute walk of Multiplaza Pacific Mall and Avenida Balboa.

JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
$269 nightly
The price is $296 total per night
$296 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Centrally located in Panama City, JW Marriott Panama is within a 15-minute walk of Multiplaza Pacific Mall and Avenida Balboa.
Pool
Spa

Marriott Panama Hotel
Roosevelt Ave., Allbrook Mall Panama City Panama
$142 nightly
The price is $156 total per night
$156 total
Dec 12 - Dec 13
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Marriott Panama Hotel places you in the heart of Panama City, steps from Albrook Shopping Mall and a 3-minute drive from Anthropological Museum Reina Torres de Arauz.

Hotel Coral Suites
Calle D El Cangrejo Panama City Panama
$67 nightly
The price is $73 total per night
$73 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Hotel Coral Suites places you in the heart of Panama City, just a 5-minute walk from Via Espana and within a 5-minute drive of Avenida Balboa.

Bristol Panama, a Registry Collection Hotel
Avenida Aquilino de La Guardia Panama City Panama
$200 nightly
The price is $220 total per night
$220 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Bristol Panama, a Registry Collection Hotel, you'll be centrally located in Panama City, steps from Calle 50 and within a 10-minute walk of Soho City Center.
Pool
Spa

Exe Oriental Panama
Avenida 2da Sur, Obarrio, Bella Vista Panama City Panama
$72 nightly
The price is $79 total per night
$79 total
Dec 13 - Dec 14
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Exe Oriental Panama in Panama City (Bella Vista), you'll be a 3-minute walk from Via Espana and 14 minutes by foot from Avenida Balboa.
Free WiFi
Restaurant

TRYP by Wyndham Panamá Centro
Via Veneto, El Cangrejo Bellavista Panama City Panama
$87 nightly
The price is $96 total per night
$96 total
Dec 18 - Dec 19
Total with taxes and fees
Free Cancellation
A stay at TRYP by Wyndham Panamá Centro places you in the heart of Panama City, within a 5-minute drive of Iglesia del Carmen and Cinta Costera.

Megapolis Hotel Panamá
Ave. Balboa al lado de Multicentro, 63 Panama City Panamá Province
With a stay at Megapolis Hotel Panamá, you'll be centrally located in Panama City, steps from Multicentro Panama and Avenida Balboa.

Hilton Garden Inn Panama City Downtown, Panama
Calle Eusebio A. Morales Panama City Panama Province
$92 nightly
The price is $101 total per night
$101 total
Dec 17 - Dec 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Hilton Garden Inn Panama City Downtown, Panama, you'll be centrally located in Panama City, just a 5-minute walk from Via Espana and 13 minutes by foot from Avenida Balboa.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Panama City hotels essential information
Accommodation | 1,633 hotels |
|---|---|
Lowest Price | $73 |
Highest Price | $296 |
Popular hotels | Hotel Riu Plaza Panama, Novotel Panama City, Doubletree By Hilton Panama City El Carmen, Courtyard by Marriott Panama Multiplaza Mall, JW Marriott Panama, Marriott Panama Hotel, Hotel Coral Suites, Bristol Panama, a Registry Collection Hotel, Exe Oriental Panama, TRYP by Wyndham Panamá Centro, Megapolis Hotel Panamá, Hilton Garden Inn Panama City Downtown, Panama |
Most Recent Panama City Hotel Reviews

Hotel Riu Plaza Panama
5 out of 5
Posted 10 hours ago
CheapTickets Verified Review
"The Staff was Amazing. Pamela at the hotels store mad my fiancé and I feel like family. The rooms are spacious and clean. "
A verified traveler stayed at Hotel Riu Plaza Panama
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