Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5
Due to coronavirus (COVID-19) travel advisories, some destinations may be unavailable for certain dates. Find out more.
Tonight
This weekend
May 29 - May 31
Next weekend
Jun 5 - Jun 7

Cheap Mayo Clinic Florida Hotels

Courtyard by Marriott Jacksonville Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville Mayo Clinic Campus/Beaches

0.3 km from Mayo Clinic Florida
    3.0 out of 5.0
     
     

    With a stay at Courtyard by Marriott Jacksonville Mayo Clinic Campus/Beaches in Jacksonville (Southside), you'll be a 1-minute drive from Mayo Clinic Florida ...

    $159

    The Petite Retreat NEW TO Vrbo

    The Petite Retreat NEW TO Vrbo

    0.4 km from Mayo Clinic Florida
       
       

      With a stay at this apartment in Jacksonville (Southside), you'll be a 1-minute drive from Mayo Clinic Florida and 6 minutes from Adventure Landing.

      The Petite Retreat NEW TO VrboGet Rates

      The Retreat NEW TO Vrbo

      The Retreat NEW TO Vrbo

      0.2 km from Mayo Clinic Florida
         
         

        With a stay at this vacation home in Jacksonville (Southside), you'll be a 1-minute drive from Mayo Clinic Florida and 6 minutes from Adventure Landing.

        The Retreat NEW TO VrboGet Rates

        Light Grey Getaway under 2 miles to mayo, 4 miles to the beach

        Light Grey Getaway under 2 miles to mayo, 4 miles to the beach

        1.3 km from Mayo Clinic Florida
           
           

          With a stay at this vacation home in Jacksonville Beach (Southside), you'll be a 4-minute drive from Mayo Clinic Florida and 6 minutes from Adventure ...

          Light Grey Getaway under 2 miles to mayo, 4 miles to the beachGet Rates

          Newly Renovated Ground Floor Condo! Close to Mayo, Beaches, Town Center.

          Newly Renovated Ground Floor Condo! Close to Mayo, Beaches, Town Center.

          1.6 km from Mayo Clinic Florida
             
             

            With a stay at this condo in Jacksonville (Southside), you'll be within a 10-minute drive of University of North Florida and Adventure Landing.

            Newly Renovated Ground Floor Condo! Close to Mayo, Beaches, Town Center.Get Rates

            Breathtaking Views! Intercoastal waterfront home w/ pool! 1 mi. from Mayo Clinc

            Breathtaking Views! Intercoastal waterfront home w/ pool! 1 mi. from Mayo Clinc

            2.2 km from Mayo Clinic Florida
               
               

              With a stay at this vacation home in Jacksonville Beach (Southside), you'll be a 4-minute drive from Adventure Landing and 6 minutes from Mayo Clinic ...

              Breathtaking Views! Intercoastal waterfront home w/ pool! 1 mi. from Mayo ClincGet Rates

              Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area

              Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area

              1.7 km from Mayo Clinic Florida
                2.5 out of 5.0
                 
                 

                Located in Jacksonville (Southside), Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area is within a 10-minute drive of Windsor Parke Golf Club and University ...

                Holiday Inn Express & Suites Jacksonville SE- Med Ctr AreaGet Rates

                Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

                Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

                2.7 km from Mayo Clinic Florida
                  2.5 out of 5.0
                   
                   

                  With a stay at Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic in Jacksonville (Southside), you'll be within a 10-minute drive of Mayo Clinic Florida ...

                  Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo ClinicGet Rates

                  Beautiful House Great Location Close to Beaches Mayo Clinic Shops Restaurants

                  Beautiful House Great Location Close to Beaches Mayo Clinic Shops Restaurants

                  2.5 km from Mayo Clinic Florida
                     
                     

                    With a stay at this vacation home in Jacksonville (Southside), you'll be within a 10-minute drive of Mayo Clinic Florida and Adventure Landing.

                    Beautiful House Great Location Close to Beaches Mayo Clinic Shops RestaurantsGet Rates

                    Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

                    Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

                    2.1 km from Mayo Clinic Florida
                      2.5 out of 5.0
                       
                       

                      When you stay at Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area in Jacksonville Beach, you'll be in the business district, within a 10-minute drive ...

                      Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic AreaGet Rates

                      Hampton Inn Jacksonville Beach/Oceanfront

                      Hampton Inn Jacksonville Beach/Oceanfront

                      4.9 km from Mayo Clinic Florida
                        3.0 out of 5.0
                         
                         

                        When you stay at Hampton Inn Jacksonville Beach/Oceanfront in Jacksonville Beach, you'll be on the beach, within a 15-minute drive of Mayo Clinic Florida and ...

                        $179

                        One Ocean Resort & Spa

                        One Ocean Resort & Spa

                        7.1 km from Mayo Clinic Florida
                          4.5 out of 5.0
                           
                           

                          Located in Atlantic Beach, One Ocean Resort & Spa is connected to a shopping center, a 1-minute drive from Beaches Town Center and 10 minutes from Dutton Island ...

                          $139

                          Map

                          Often, one of the most difficult things about booking a hotel is finding the best time to go. The cost of staying in hotels in could vary significantly, depending on the time of the year chosen. If you would like to figure out the most suitable time to take a trip then using CheapTickets could be the best option for you. We will be able to provide information on hotels in to ensure that you get the best deal possible. So if you are looking for a booking website that will streamline the process and offer good prices, then log in and get booking.

                          Most Recent Mayo Clinic Florida Hotel Reviews

                          *Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.