Compare Cheap Hotels in Isle of Palms Florida

With a stay at Residence Inn By Marriott Jacksonville - Mayo Clinic Area in Jacksonville (Isle of Palms), you'll be a 1-minute drive from Mayo Clinic Florida and 9 minutes from St. Johns Town Center.

With a stay at Margaritaville Jacksonville Beach in Jacksonville Beach (Oceanfront), you'll be a 1-minute drive from Jacksonville Beach Pier and 9 minutes from Mayo Clinic Florida.

Located in Jacksonville (Southside), Wyndham Garden Jacksonville is within a 10-minute drive of St. Johns Town Center and University of North Florida.

Hyatt Regency Jacksonville is centrally located in Jacksonville, a 4-minute walk from Florida Theatre and 11 minutes by foot from Times-Union Center for the Performing Arts.

With a stay at Hyatt Place Jacksonville / St. Johns Town Center in Jacksonville (Southside), you'll be within a 5-minute drive of St. Johns Town Center and University of North Florida.

With a stay at Hampton Inn Jacksonville Beach/Oceanfront in Jacksonville Beach (Oceanfront), you'll be a 2-minute drive from Jacksonville Beach Pier and 10 minutes from Mayo Clinic Florida.

With a stay at Omni Amelia Island Resort & Spa in Fernandina Beach, you'll be 2.9 mi (4.7 km) from Fort George Island Cultural State Park and 8.9 mi (14.3 km) from Fort Clinch State Park.

With a stay at The Villas of Amelia Island in Fernandina Beach, you'll be 1.3 mi (2 km) from Fort George Island Cultural State Park and 10 mi (16 km) from Fort Clinch State Park.

Best Western Oceanfront is centrally located in Jacksonville Beach, a 3-minute walk from Jacksonville Beach Pier and 11 minutes by foot from Oceanfront Park.

With a stay at Extended Stay America Premier Suites - Jacksonville - Airport in Jacksonville (Northside), you'll be within a 10-minute drive of Jacksonville Zoo and Gardens and UF Health Hospital North.

With a stay at Marriott Jacksonville Downtown, you'll be centrally located in Jacksonville, steps from Times-Union Center for the Performing Arts and within a 10-minute walk of Museum of Contemporary Art Jacksonville.

With a stay at Holiday Inn Express Jacksonville South Bartram Prk by IHG in Jacksonville, you'll be in the business district, within a 15-minute drive of St. Johns Town Center and Baptist Medical Center South.