Compare Cheap Hotels in Isle of Palms Florida

With a stay at Residence Inn By Marriott Jacksonville - Mayo Clinic Area in Jacksonville (Isle of Palms), you'll be a 1-minute drive from Mayo Clinic Florida and 9 minutes from St. Johns Town Center.

With a stay at Margaritaville Jacksonville Beach in Jacksonville Beach (Oceanfront), you'll be within a 15-minute drive of Mayo Clinic Florida and Mayport Naval Station.

Hyatt Regency Jacksonville is centrally located in Jacksonville, a 4-minute walk from Florida Theatre and 11 minutes by foot from Jacksonville Center for the Performing Arts.

When you stay at Embassy Suites by Hilton Jacksonville Baymeadows in Jacksonville, you'll be in the business district, within a 15-minute drive of St. Johns Town Center and University of North Florida.

With a stay at Scottish Inn Jacksonville Downtown in Jacksonville (San Marco), you'll be within a 10-minute drive of VyStar Veterans Memorial Arena and EverBank Stadium.

Located in Jacksonville (Southside), Wyndham Garden Jacksonville is within a 10-minute drive of St. Johns Town Center and University of North Florida.

With a stay at The Villas of Amelia Island in Fernandina Beach, you'll be 1.3 mi (2 km) from Fort George Island Cultural State Park and 10 mi (16 km) from Fort Clinch State Park.

With a stay at Omni Amelia Island Resort & Spa in Fernandina Beach, you'll be 2.9 mi (4.7 km) from Fort George Island Cultural State Park and 8.9 mi (14.3 km) from Fort Clinch State Park.

With a stay at Hampton Inn Jacksonville Beach/Oceanfront in Jacksonville Beach (Oceanfront), you'll be within a 15-minute drive of Mayo Clinic Florida and Mayport Naval Station.

With a stay at Hyatt Place Jacksonville Airport in Jacksonville (Northside), you'll be within a 10-minute drive of Jacksonville Zoo and Gardens and UF Health Hospital North.

With a stay at Weekly Inn, you'll be centrally located in Jacksonville, within a 10-minute drive of EverBank Stadium and VyStar Veterans Memorial Arena.

When you stay at Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area in Jacksonville Beach, you'll be in the business district, a 4-minute drive from Mayo Clinic Florida and 10 minutes from University of North Florida.