Compare Cheap Hotels in Isle of Palms Florida

With a stay at Residence Inn By Marriott Jacksonville - Mayo Clinic Area in Jacksonville (Isle of Palms), you'll be a 1-minute drive from Mayo Clinic Florida and 9 minutes from St. Johns Town Center.

With a stay at Margaritaville Jacksonville Beach in Jacksonville Beach (Oceanfront), you'll be a 1-minute drive from Jacksonville Beach Pier and 9 minutes from Mayo Clinic Florida.

Hyatt Regency Jacksonville is centrally located in Jacksonville, a 4-minute walk from Florida Theatre and 11 minutes by foot from Jacksonville Center for the Performing Arts.

With a stay at The Villas of Amelia Island in Fernandina Beach, you'll be 1.3 mi (2 km) from Fort George Island Cultural State Park and 10 mi (16 km) from Fort Clinch State Park.

With a stay at Scottish Inn Jacksonville Downtown in Jacksonville (San Marco), you'll be within a 10-minute drive of VyStar Veterans Memorial Arena and EverBank Stadium.

When you stay at Embassy Suites by Hilton Jacksonville Baymeadows in Jacksonville, you'll be in the business district, within a 15-minute drive of St. Johns Town Center and University of North Florida.

With a stay at Omni Amelia Island Resort & Spa in Fernandina Beach, you'll be 2.9 mi (4.7 km) from Fort George Island Cultural State Park and 8.9 mi (14.3 km) from Fort Clinch State Park.

With a stay at Hampton Inn Jacksonville Beach/Oceanfront in Jacksonville Beach (Oceanfront), you'll be a 2-minute drive from Jacksonville Beach Pier and 10 minutes from Mayo Clinic Florida.

Located in Jacksonville (Southside), Wyndham Garden Jacksonville is within a 10-minute drive of St. Johns Town Center and University of North Florida.

With a stay at Springhill Suites By Marriott Jacksonville Beach Oceanfront in Jacksonville Beach (Oceanfront), you'll be a 1-minute drive from Jacksonville Beach Pier and 9 minutes from Mayo Clinic Florida.

With a stay at Home2 Suites by Hilton Jacksonville Airport in Jacksonville (Northside), you'll be within a 10-minute drive of Jacksonville Zoo and Gardens and UF Health North.

With a stay at Weekly Inn, you'll be centrally located in Jacksonville, within a 10-minute drive of EverBank Stadium and VyStar Veterans Memorial Arena.