Compare Cheap Hotels in Isle of Palms Florida

With a stay at Residence Inn By Marriott Jacksonville - Mayo Clinic Area in Jacksonville (Isle of Palms), you'll be a 3-minute drive from Mayo Clinic Florida and 9 minutes from St. Johns Town Center.

When you stay at Margaritaville Jacksonville Beach in Jacksonville Beach, you'll be on the beach, within a 15-minute drive of Mayo Clinic Florida and Mayport Naval Station.

Located in Jacksonville (Southside), Wyndham Garden Jacksonville is within a 10-minute drive of St. Johns Town Center and University of North Florida.

Hyatt Regency Jacksonville is centrally located in Jacksonville, a 4-minute walk from Florida Theatre and 11 minutes by foot from Times-Union Center for the Performing Arts.

When you stay at Hampton Inn Jacksonville Beach/Oceanfront in Jacksonville Beach, you'll be on the beach, within a 15-minute drive of Mayport Naval Station and Mayo Clinic Florida.

When you stay at Embassy Suites by Hilton Jacksonville Baymeadows in Jacksonville, you'll be in the business district, within a 15-minute drive of St. Johns Town Center and Mayo Clinic Florida.

With a stay at The Villas of Amelia Island in Fernandina Beach, you'll be 1.3 mi (2 km) from Fort George Island Cultural State Park and 10 mi (16 km) from Fort Clinch State Park.

With a stay at Weekly Inn, you'll be centrally located in Jacksonville, within a 10-minute drive of EverBank Stadium and VyStar Veterans Memorial Arena.

With a stay at Extended Stay America Premier Suites - Jacksonville - Airport in Jacksonville (Northside), you'll be within a 10-minute drive of Jacksonville Zoo and Gardens and UF Health Hospital North.

When you stay at Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area in Jacksonville Beach, you'll be in the business district, within a 10-minute drive of Mayo Clinic Florida and University of North Florida.

With a stay at Hyatt Place Jacksonville Airport in Jacksonville (Northside), you'll be within a 10-minute drive of Jacksonville Zoo and Gardens and UF Health North.

A stay at Southbank Hotel by Marriott Jacksonville Riverwalk places you in the heart of Jacksonville, within a 5-minute drive of Baptist Medical Center Jacksonville and VyStar Veterans Memorial Arena.