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Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property

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Photo gallery for Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Lobby lounge
Bar (on property)
Reception
Reception
Exterior

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
The current price is $157
$139 nightly
$157 total
Total with taxes and fees
May 8 - May 9

Explore the area

View in a map
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL, 32224
  • Place, University of North Florida
    ‪6 min drive‬
  • Place, St. Johns Town Center
    ‪9 min drive‬
  • Place, Mayport Naval Station
    ‪16 min drive‬
  • Airport, Jacksonville, FL (JAX-Jacksonville Intl.)
    ‪38 min drive‬

Room options

View all photos for Studio, 1 King Bed with Sofa bed, Corner

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed, Corner

9.8 out of 10
Exceptional
(6 reviews)
  • 533 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom, Corner

Studio Suite, 1 Bedroom, Corner | In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 Bedroom, Corner

10.0 out of 10
Exceptional
(3 reviews)
  • 646 sq ft
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed

Fridge, microwave, stovetop, dishwasher

Studio Suite, 1 King Bed with Sofa bed

9.6 out of 10
Exceptional
(90 reviews)
  • 407 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom

Studio Suite, 1 Bedroom | Living room | 55-inch Smart TV with cable channels, TV, Netflix

Studio Suite, 1 Bedroom

9.8 out of 10
Exceptional
(17 reviews)
  • 560 sq ft
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

8.8 out of 10
Excellent
(6 reviews)
  • 409 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed with Sofa bed (Hearing Accessible)

8.0 out of 10
Very good
(1 review)
  • 391 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Roll-In Shower)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Roll-In Shower)

  • 391 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 Bedroom (Hearing Accessible)

8.0 out of 10
Very good
(1 review)
  • 569 sq ft
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed, Corner (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed, Corner (Hearing Accessible)

9.0 out of 10
Wonderful
(2 reviews)
  • 538 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom, Corner (Mobility/Hearing Access, Roll-In Shwr)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 Bedroom, Corner (Mobility/Hearing Access, Roll-In Shwr)

  • 641 sq ft
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

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About the neighborhood

Jacksonville

With a stay at Residence Inn By Marriott Jacksonville - Mayo Clinic Area in Jacksonville (Isle of Palms), you'll be a 3-minute drive from Mayo Clinic Florida and 9 minutes from St. Johns Town Center. .This hotel is 10.3 mi (16.5 km) from Mayport Naval Station and 5.2 mi (8.4 km) from University of North Florida.

What's nearby

  • University of North Florida - 6 min drive - 5.6 miles
  • St. Johns Town Center - 9 min drive - 7.6 miles
  • TPC Sawgrass - 12 min drive - 8.7 miles
  • Mayport Naval Station - 16 min drive - 11.2 miles
  • Jacksonville Naval Air Station - 32 min drive - 29.6 miles

Getting around

  • Jacksonville, FL (CRG-Jacksonville Executive at Craig) - 17 min drive

Restaurants

  • ‪Culver’s - ‬4 min drive
  • ‪Starbucks - ‬4 min drive
  • ‪Circle K - ‬9 min walk
  • ‪Starbucks - ‬3 min drive
  • ‪M Brothers at Mayo - ‬17 min walk

About this property

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area offers 155 air-conditioned accommodations with laptop-compatible safes and coffee/tea makers. Accommodations offer separate sitting areas. 55-inch Smart televisions come with premium cable channels and Netflix. Accommodations at this 3-star hotel have kitchens with refrigerators, stovetops, microwaves, and separate dining areas. Bathrooms include bathtubs or showers, complimentary toiletries, and hair dryers.

This Jacksonville hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones. Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is offered daily and change of bedsheets can be requested. Housekeeping is provided on request.

Recreational amenities at the hotel include an outdoor pool and a 24-hour fitness center.
Make yourself at home in one of the 155 air-conditioned rooms featuring kitchens with refrigerators and stovetops. 55-inch Smart televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Conveniences include phones, as well as laptop-compatible safes and desks.
Be sure to enjoy recreational amenities including an outdoor pool and a 24-hour fitness center. This hotel also features complimentary wireless internet access, concierge services, and wedding services.
Grab a bite from the grocery/convenience store serving guests of Residence Inn By Marriott Jacksonville - Mayo Clinic Area. Relax with your favorite drink at the bar/lounge or the poolside bar. A complimentary buffet breakfast is served on weekdays from 6:30 AM to 9:00 AM and on weekends from 7:00 AM to 9:30 AM.
Featured amenities include a 24-hour business center, express check-out, and complimentary newspapers in the lobby. Planning an event in Jacksonville? This hotel has 2678 square feet (249 square meters) of space consisting of conference space and 2 meeting rooms. Free self parking is available onsite.
A complimentary buffet breakfast is served on weekdays between 6:30 AM and 9:00 AM and on weekends between 7:00 AM and 9:30 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free uncovered self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available 6:30 AM to 9:00 AM on weekdays and 7:00 AM to 9:30 AM on weekends
  • A bar/lounge
  • A poolside bar
  • Coffee and tea in common areas

Things to do

  • 24-hour gym
  • Outdoor pool
  • TV in common areas

Family friendly

  • Grocery/convenience store
  • In-room kitchen
  • In-room microwave
  • In-room refrigerator
  • Laundry facilities
  • Outdoor pool
  • Separate in-room dining area

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Water dispenser

Guest services

  • Change of bedsheets (on request)
  • Concierge services
  • Dry cleaning/laundry service
  • Free grocery shopping service
  • Housekeeping (daily)
  • Multilingual staff
  • Wedding services

Business services

  • 2 meeting rooms
  • 2,678 square feet of conference space
  • 24-hour business center
  • Computer station
  • Coworking space

Outdoors

  • Barbecue grill
  • Garden
  • Picnic area
  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Accessible bathtub
  • Assistive listening devices
  • Assistive listening devices in meeting rooms
  • Bathroom emergency pull cord
  • Braille/raised signage
  • Elevator
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • Lever door handles
  • Low-height bed
  • Low-height counter and sink
  • Low-height door lock
  • Low-height electrical outlets in bathroom
  • Low-height view port in door
  • Phone accessibility kit
  • Pool hoist on site
  • Raised toilet seat
  • Stair-free path to entrance
  • Vibrating pillow alarm
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking
  • Wheelchair-width doorways

More

  • 1 building
  • 7 floors
  • At least 80% lighting from LEDs
  • Ballroom
  • Banquet hall
  • Biodegradable coffee stirrers available
  • Built in 2020
  • Communal living room
  • Comprehensive food waste policy
  • Comprehensive recycling policy
  • Double-glazed windows
  • Fireplace in lobby
  • No plastic coffee stirrers
  • Smoking not allowed
  • Traditional architecture
  • Vegan dining options
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathtub or shower
  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 55-inch smart TV with premium cable channels
  • Netflix
  • Streaming services

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Kitchen
  • Microwave
  • Refrigerator
  • Separate dining area
  • Stovetop
  • Toaster

More

  • Air conditioning
  • Connecting rooms available
  • Desk
  • Energy-saving switches in guestrooms
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • LED lighting
  • Mobile key entry
  • Phone
  • Recycling
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 6:00 AM
Contactless check-in available
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
If you are planning to arrive after 11:00 PM please contact the property in advance using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 150 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total (up to 40 lbs per pet)
Restrictions apply; for more information contact the property at the number on the booking confirmation

Children and extra beds

Children are welcome
Cribs (infant beds) are not available

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Deposit: USD 125 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Pet fee: USD 150 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, and window guards
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)

We should mention

Only registered guests are allowed in the guestrooms
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Residence INN BY Marriott Jacksonville
Residence Inn by Marriott Jacksonville East
Residence Inn Jacksonville Mayo Clinic Area
Residence Inn By Marriott Jacksonville - Mayo Clinic Area Hotel

Residence Inn By Marriott Jacksonville - Mayo Clinic Area Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 389 out of 492 reviews
Rating 8 - Good. 70 out of 492 reviews
Rating 6 - Okay. 13 out of 492 reviews
Rating 4 - Poor. 14 out of 492 reviews
Rating 2 - Terrible. 6 out of 492 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.0/10

Amenities

9.6/10

Property conditions & facilities

Reviews

8/10 Good

Kimberly

Liked: Cleanliness, staff & service, amenities
Clean rooms and amenities.
Stayed 4 nights in Jan 2026

10/10 Excellent

LaQuinta

Stayed 1 night in Jan 2026

10/10 Excellent

STEVEN

Stayed 2 nights in Jan 2026

10/10 Excellent

Darlene

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Clean room, amazing staff great location
Stayed 1 night in Dec 2025

10/10 Excellent

Gary

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Jan 2026

10/10 Excellent

Catherine

Stayed 2 nights in Jan 2026

4/10 Poor

Nirvana

Traveled with family
Disliked: Cleanliness, staff & service, amenities, property conditions & facilities
We paid top dollar $396-296 per night for housekeeper to NOT even make our beds, the bed was lumpy, extremely uncomfortable to sleep, had to keep calling for towels (even though I asked for it to be noted daily), the breakfast was powder eggs, horrible tasting sausages, the housekeeper never left enough pillows for the pull out, the fridge had food from prior guests and the shower had half glass enclosure which kept making it IMPOSSIBLE to keep the floor in the bathroom dry Horrible design, dont know which contractor thought of that also the shower head was palced at least 6 feet above sp for ahorter ppl or kids you couldn't access thr hose. What a shame!
Stayed 3 nights in Jan 2026

10/10 Excellent

Daniel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Coffee pot was dirty. Seems to be the case with all hotels but make sure its clean and you will stand out.
Stayed 3 nights in Jan 2026

10/10 Excellent

STEVEN

Liked: Cleanliness, staff & service, amenities
Conveniently located, clean rooms, excellent breakfast
Stayed 2 nights in Jan 2026

10/10 Excellent

Wayne

Liked: Cleanliness, amenities, property conditions & facilities
The staff was great at check in and the bar. Room was very clean, but the couch needed to be replaced.
Stayed 1 night in Jan 2026

10/10 Excellent

James

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
excellent.ent
Stayed 1 night in Dec 2025

10/10 Excellent

Jerale

Stayed 1 night in Dec 2025

10/10 Excellent

Alan

Stayed 1 night in Dec 2025

6/10 Okay

Ryan

Stayed 1 night in Dec 2025

10/10 Excellent

Joseph

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Clean, convenient to interstate, Mayo Hospital, 10 minutes from numerous restaurants and shopping. The staff was friendly.
Stayed 1 night in Dec 2025

10/10 Excellent

Linda Diane

Traveled with family
Liked: Cleanliness, staff & service, amenities
Spotless room, wonderful staff, and great amenties. Everything is provided!! Kitchen is supplied, bathroom has extras, shampoo, conditioner, and body bath!! Very quiet rooms can not here anything once you get into your room!
Stayed 2 nights in Nov 2025

10/10 Excellent

William

Stayed 22 nights in Nov 2025

10/10 Excellent

Jamie

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Great
Stayed 1 night in Nov 2025

10/10 Excellent

Bonnie, Ormond Beach

Liked: Cleanliness, staff & service, property conditions & facilities
Very nice hotel - clean, quiet and the most convenient to the Mayo Clinic.
Stayed 1 night in Nov 2025

10/10 Excellent

Jacob

All was good
Stayed 1 night in Nov 2025

6/10 Okay

David

Liked: Cleanliness, property conditions & facilities
Marriot… a room refresh does not include making the bed? WTAF?! Also, no smoking means no smoking. A man smoked a cigar in the court yard without any interference from the staff. It’s too bad, the room was spacious and clean but the follow through in non existent.
Stayed 3 nights in Nov 2025

10/10 Excellent

Teresa

Stayed 1 night in Nov 2025

10/10 Excellent

Kimberly

Business traveler, Traveled with partner, Traveled with pets
Liked: Cleanliness, amenities, property conditions & facilities
Yes room was clean!! We appreciate being able to add an additional nights stay, as we encountered an emergency overnight Stay at the hospital. Mayo Clinic patient.
Stayed 3 nights in Oct 2025

10/10 Excellent

Danielle

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Nov 2025

10/10 Excellent

Nia

Stayed 3 nights in Oct 2025