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Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property

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Photo gallery for Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Lobby
Bar (on property)
Reception
Reception
Exterior

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
The current price is $176
$155 nightly
$176 total
Total with taxes and fees
Jul 19 - Jul 20

Explore the area

View in a map
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL, 32224
  • Place, University of North Florida
    ‪5 min drive‬
  • Place, St. Johns Town Center
    ‪8 min drive‬
  • Place, Mayport Naval Station
    ‪24 min drive‬
  • Airport, Jacksonville, FL (JAX-Jacksonville Intl.)
    ‪34 min drive‬

Room options

View all photos for Studio, 1 King Bed with Sofa bed, Corner

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed, Corner

9.8 out of 10
Exceptional
(6 reviews)
  • 533 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio Suite, 1 Bedroom, Corner

Studio Suite, 1 Bedroom, Corner | In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 Bedroom, Corner

10.0 out of 10
Exceptional
(3 reviews)
  • 646 sq ft
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio Suite, 1 King Bed with Sofa bed

Fridge, microwave, stovetop, dishwasher

Studio Suite, 1 King Bed with Sofa bed

9.6 out of 10
Exceptional
(97 reviews)
  • 407 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio Suite, 1 Bedroom

Studio Suite, 1 Bedroom | Living room | 55-inch Smart TV with cable channels, TV, Netflix

Studio Suite, 1 Bedroom

9.8 out of 10
Exceptional
(21 reviews)
  • 560 sq ft
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

9.0 out of 10
Wonderful
(8 reviews)
  • 409 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio Suite, 1 King Bed with Sofa bed (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed with Sofa bed (Hearing Accessible)

9.0 out of 10
Wonderful
(2 reviews)
  • 391 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Roll-In Shower)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Roll-In Shower)

  • 391 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio Suite, 1 Bedroom (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 Bedroom (Hearing Accessible)

8.0 out of 10
Very good
(1 review)
  • 569 sq ft
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed, Corner (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed, Corner (Hearing Accessible)

9.0 out of 10
Wonderful
(2 reviews)
  • 538 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio Suite, 1 Bedroom, Corner (Mobility/Hearing Access, Roll-In Shwr)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 Bedroom, Corner (Mobility/Hearing Access, Roll-In Shwr)

  • 641 sq ft
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free WiFi

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Jun 21 - Jun 22
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About the neighborhood

Jacksonville

With a stay at Residence Inn By Marriott Jacksonville - Mayo Clinic Area in Jacksonville (Isle of Palms), you'll be a 3-minute drive from Mayo Clinic Florida and 9 minutes from St. Johns Town Center. .This hotel is 10.3 mi (16.5 km) from Mayport Naval Station and 5.2 mi (8.4 km) from University of North Florida.

What's nearby

  • University of North Florida - 5 min drive - 5.6 miles
  • St. Johns Town Center - 8 min drive - 7.9 miles
  • TPC Sawgrass - 15 min drive - 8.1 miles
  • Mayport Naval Station - 24 min drive - 11.6 miles
  • Jacksonville Naval Air Station - 29 min drive - 30.3 miles

Getting around

  • Jacksonville, FL (CRG-Jacksonville Executive at Craig) - 17 min drive

Restaurants

  • ‪Culver’s - ‬4 min drive
  • ‪Circle K - ‬9 min walk
  • ‪Starbucks - ‬4 min drive
  • ‪Mayo Clinic - Employee Cafeteria - ‬18 min walk
  • ‪M Brothers at Mayo - ‬17 min walk

About this property

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area offers 155 air-conditioned accommodations with laptop-compatible safes and coffee/tea makers. Accommodations offer separate sitting areas. 55-inch Smart televisions come with premium cable channels and Netflix. Accommodations at this 3-star hotel have kitchens with refrigerators, stovetops, microwaves, and separate dining areas. Bathrooms include bathtubs or showers, complimentary toiletries, and hair dryers.

This Jacksonville hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones. Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is offered daily and change of bedsheets can be requested. Housekeeping is provided on request.

Recreational amenities at the hotel include an outdoor pool and a 24-hour fitness center.
Make yourself at home in one of the 155 air-conditioned rooms featuring kitchens with refrigerators and stovetops. 55-inch Smart televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Conveniences include phones, as well as laptop-compatible safes and desks.
Be sure to enjoy recreational amenities including an outdoor pool and a 24-hour fitness center. This hotel also features complimentary wireless internet access, concierge services, and wedding services.
Grab a bite from the grocery/convenience store serving guests of Residence Inn By Marriott Jacksonville - Mayo Clinic Area. Relax with your favorite drink at the bar/lounge or the poolside bar. A complimentary buffet breakfast is served on weekdays from 6:30 AM to 9:00 AM and on weekends from 7:00 AM to 9:30 AM.
Featured amenities include a 24-hour business center, express check-out, and complimentary newspapers in the lobby. Planning an event in Jacksonville? This hotel has 2678 square feet (249 square meters) of space consisting of conference space and 2 meeting rooms. Free self parking is available onsite.
A complimentary buffet breakfast is served on weekdays between 6:30 AM and 9:00 AM and on weekends between 7:00 AM and 9:30 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free uncovered self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available 6:30 AM to 9:00 AM on weekdays and 7:00 AM to 9:30 AM on weekends
  • A bar/lounge
  • A poolside bar
  • Coffee and tea in common areas

Things to do

  • 24-hour gym
  • Outdoor pool
  • TV in common areas

Family friendly

  • Grocery/convenience store
  • In-room kitchen
  • In-room microwave
  • In-room refrigerator
  • Laundry facilities
  • Outdoor pool
  • Separate in-room dining area

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Water dispenser

Guest services

  • Change of bedsheets (on request)
  • Concierge services
  • Dry cleaning/laundry service
  • Free grocery shopping service
  • Housekeeping (daily)
  • Multilingual staff
  • Wedding services

Business services

  • 2 meeting rooms
  • 2,678 square feet of conference space
  • 24-hour business center
  • Computer station
  • Coworking space

Outdoors

  • Barbecue grill
  • Garden
  • Picnic area
  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Accessible bathtub
  • Assistive listening devices
  • Assistive listening devices in meeting rooms
  • Bathroom emergency pull cord
  • Braille/raised signage
  • Elevator
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • Lever door handles
  • Low-height bed
  • Low-height counter and sink
  • Low-height door lock
  • Low-height electrical outlets in bathroom
  • Low-height view port in door
  • Phone accessibility kit
  • Pool hoist on site
  • Raised toilet seat
  • Stair-free path to entrance
  • Vibrating pillow alarm
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking
  • Wheelchair-width doorways

More

  • 1 building
  • 7 floors
  • Ballroom
  • Banquet hall
  • Built in 2020
  • Communal living room
  • Comprehensive food waste policy
  • Double-glazed windows
  • Fireplace in lobby
  • No plastic coffee stirrers
  • Non-plastic coffee stirrers available
  • Smoking not allowed
  • Some LED lighting used
  • Traditional architecture
  • Vegan dining options
  • Vegetarian breakfast available
  • Vegetarian dining options
  • Waste recycling policy

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathtub or shower
  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 55-inch smart TV with premium cable channels
  • Netflix
  • Streaming services

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Kitchen
  • Microwave
  • Refrigerator
  • Separate dining area
  • Stovetop
  • Toaster

More

  • Air conditioning
  • Connecting rooms available
  • Desk
  • Energy-saving switches used
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • LED lighting
  • Mobile key entry
  • Phone
  • Recycling
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 6:00 AM
Contactless check-in available
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
If you are planning to arrive after 11:00 PM please contact the property in advance using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 150 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total (up to 40 lbs per pet)
Restrictions apply; for more information contact the property at the number on the booking confirmation

Children and extra beds

Children are welcome
Cribs (infant beds) are not available

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Deposit: USD 125 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Pet fee: USD 150 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, and window guards
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)

We should mention

Only registered guests are allowed in the guestrooms
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Residence INN BY Marriott Jacksonville
Residence Inn by Marriott Jacksonville East
Residence Inn Jacksonville Mayo Clinic Area
Residence Inn By Marriott Jacksonville - Mayo Clinic Area Hotel

Residence Inn By Marriott Jacksonville - Mayo Clinic Area Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 434 out of 541 reviews
Rating 8 - Good. 72 out of 541 reviews
Rating 6 - Okay. 14 out of 541 reviews
Rating 4 - Poor. 14 out of 541 reviews
Rating 2 - Terrible. 7 out of 541 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.2/10

Amenities

9.6/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Sabrena

Great stay! Clean room, friendly staff.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

STEVEN

Liked: Cleanliness, staff & service, amenities
Conveniently located, clean rooms, excellent breakfast
Stayed 2 nights in Jan 2026
Verified

8/10 Good

M

Liked: Cleanliness, staff & service, property conditions & facilities
Good location to multiple attractions in the city. Love the free and easily accessible parking.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Darlene

Liked: Cleanliness, amenities, property conditions & facilities
Clean room, amazing staff great location
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Astraes

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the size of the rooms, the kitchen, the amazing breakfast and the helpful staff. Only complaint would be to have more towels available.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Raymond

Liked: Cleanliness, staff & service, amenities
Wonderful room, clean and comfortable. The staff is great
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Vivien

Liked: Cleanliness, amenities, property conditions & facilities
Gret Hotel
Stayed 6 nights in Feb 2026
Verified

10/10 Excellent

Stephen

Liked: Cleanliness, amenities, property conditions & facilities
Great room
Stayed 1 night in Feb 2026
Verified

8/10 Good

Kimberly

Liked: Cleanliness, staff & service, amenities
Clean rooms and amenities.
Stayed 4 nights in Jan 2026
Verified

10/10 Excellent

james

Liked: Cleanliness, staff & service, property conditions & facilities
Excellent place to Stay!!
Stayed 1 night in Jul 2025
Verified

10/10 Excellent

Gary

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great facility to stay.
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Bonnie

Liked: Cleanliness, staff & service, property conditions & facilities
Very nice hotel - clean, quiet and the most convenient to the Mayo Clinic.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Kay

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Always comfortable, beautiful rooms, great beds, great service, spotless clean
Stayed 1 night in Oct 2025
Verified

8/10 Good

Kimberly

Liked: Cleanliness
Staff and amenities
Stayed 5 nights in Jan 2026
Verified

10/10 Excellent

Wayne

Liked: Cleanliness, amenities, property conditions & facilities
The staff was great at check in and the bar. Room was very clean, but the couch needed to be replaced.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Joseph

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Clean, convenient to interstate, Mayo Hospital, 10 minutes from numerous restaurants and shopping. The staff was friendly.
Stayed 1 night in Dec 2025
Verified

8/10 Good

Gerard

Liked: Cleanliness, staff & service, property conditions & facilities
Was perfect place to stay on my visit to Mayo.
Stayed 2 nights in Dec 2024
Verified

10/10 Excellent

Carolyn

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent accommodations!
Stayed 1 night in May 2025
Verified

8/10 Good

Anishma

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved my stay!
Stayed 1 night in Dec 2024
Verified

10/10 Excellent

James

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
excellent.ent
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Carrie

Liked: Cleanliness, amenities, property conditions & facilities
The place was clean and staff was wonderful. Will be staying again!
Stayed 1 night in Jun 2025
Verified

10/10 Excellent

KENNETH

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Property was clean, fairly new, comfortable, and the staff was friendly and helpful.
Stayed 2 nights in Jul 2025
Verified

10/10 Excellent

Patricia

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Definitely will be staying here anytime we are in

stayed here for a mayo clinic appointment everything was amazing from the time of check-in to check-out.
Stayed 3 nights in Feb 2025
Verified

10/10 Excellent

Sara

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place highly recommend
Stayed 2 nights in Mar 2025
Verified

10/10 Excellent

MJ

Liked: Cleanliness, staff & service, property conditions & facilities
Always a nice stay.
Stayed 1 night in Aug 2024