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Amazing PDX to SAN Flight Deals
The cheapest flights to San Diego Intl. were $165 for round trip flights and $80 for one-way flights in the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
PDX
Portland
SAN
San Diego
$165 Roundtrip, found 23 hours ago
$165
Roundtrip
found 23 hours ago
PDX
Portland
SAN
San Diego
$165 Roundtrip, found 23 hours ago
$165
Roundtrip
found 23 hours ago
PDX
Portland
SAN
San Diego
$165 Roundtrip, found 23 hours ago
$165
Roundtrip
found 23 hours ago
PDX
Portland
SAN
San Diego
$175 Roundtrip, found 23 hours ago
$175
Roundtrip
found 23 hours ago
PDX
Portland
SAN
San Diego
$178 Roundtrip, found 23 hours ago
$178
Roundtrip
found 23 hours ago
PDX
Portland
SAN
San Diego
$180 Roundtrip, found 23 hours ago
$180
Roundtrip
found 23 hours ago
Hotels near San Diego Intl. Airport (SAN)
Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
$169 nightly
The price is $194 total per night from May 25 to May 26
$194 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
8.4/10 Very Good! (3,502 reviews)
Had a great weekend stay here. Beautiful views and a great location, so close to the airport. Will be coming back soon.
Reviewed on Apr 29, 2026
Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from May 3 to May 4
$211 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
8.4/10 Very Good! (6,128 reviews)
Rooms are a little dated but okay, the balcony is nice. The parking is ridiculously priced $50 a day. The hotel is three buildings so there are a lot of people around. Water bottle refill machine in our building didn’t work.
Reviewed on Apr 30, 2026
The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
$119 nightly
The price is $138 total per night from May 25 to May 26
$138 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
8.8/10 Excellent! (1,479 reviews)
Great location. Easy to walk to the convention center and very close to a bunch of great restaurants in Little Italy. The breakfast was very good. The staff were very helpful with any questions and were very nice and super friendly. The entire place was clean and had a good vibe overall. I would ...
Reviewed on Apr 30, 2026
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Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
$152 nightly
The price is $175 total per night from May 11 to May 12
$175 total
May 11 - May 12
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in our reviews. Popular attractions USS Midway Museum and Port of San Diego are located nearby.
9.2/10 Wonderful! (3,554 reviews)
This is my go to spot on SD.
Reviewed on Apr 30, 2026
The Sofia Hotel
150 W Broadway San Diego CA
$161 nightly
The price is $186 total per night from May 11 to May 12
$186 total
May 11 - May 12
Total with taxes and fees
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
8.6/10 Excellent! (1,972 reviews)
Beautiful property at an excellent price!
Reviewed on Apr 29, 2026
Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
$236 nightly
The price is $274 total per night from May 25 to May 26
$274 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. Popular attractions USS Midway Museum and Port of San Diego are located nearby.
9/10 Wonderful! (2,839 reviews)
The Manchester Hyatt always delivers as expected. They have valet and bellhop which is important to me traveling with a special needs child and I need the convenience of having some help moving all of the luggage up to the room and parking the car for us. The room was well appointed and clean. They ...
Reviewed on Apr 25, 2026
Wyndham Garden San Diego Near SeaWorld
3737 Sports Arena Blvd San Diego CA
$113 nightly
The price is $130 total per night from May 7 to May 8
$130 total
May 7 - May 8
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy parking (surcharge), a 24-hour front desk, and a business center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Bay and Mission Beach are located nearby.
7.4/10 Good! (4,203 reviews)
Nice place , good location
Reviewed on Apr 29, 2026
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place San Diego CA
$116 nightly
The price is $133 total per night from May 10 to May 11
$133 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Mission Bay and San Diego Zoo are located nearby.
8/10 Very Good! (2,607 reviews)
Clean room and great customer service.
Reviewed on Apr 29, 2026
Don't see what you're looking for?
See all available properties in San Diego Intl.
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Picks
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