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General Mitchell International Airport (MKE) is a mere six miles south of downtown Milwaukee via I-94. The MCTS Route 80 bus connects downtown to the airport if you prefer public transportation and trains also stop by the airport.
Typical flight times from MKE to San Francisco International Airport (SFO) are just over four hours and SFO is just a couple miles from downtown.
San Francisco is a sightseer's paradise; there are countless historic sites to visit. Alcatraz Island, and the prison that stands upon it, has long been the subject of folklore and American fiction.
A walk across the Golden Gate Bridge offers a gorgeous view of the bay area, especially at sunset. The city's legendary Chinatown is the largest in the United States (walking tours are available).
You can make your way around the city via the historic cable car system, which is still fully functional and serves thousands of people every day.
San Francisco weather is normally very comfortable. Temperatures rarely drop below 50, even during the winter months, and precipitation is very light. The summer months see highs into the 80s, but bring a jacket; nights can be chilly on the bay.