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Featured Southwest Houston Hotels with Air Conditioning

Comfort Inn & Suites Southwest Fwy at Westpark

Comfort Inn & Suites Southwest Fwy at Westpark

2.5 out of 5
6687 Southwest Fwy Houston TX
$66 nightly
The price is $77 total per night
$77 total
Jul 21 - Jul 22
Total with taxes and fees
Free Cancellation
A stay at Comfort Inn & Suites Southwest Fwy at Westpark places you in the heart of Houston, a 3-minute drive from Houston Baptist University and 7 minutes from Lakewood Church.
Quality Inn & Suites NRG Park - Medical Center

Quality Inn & Suites NRG Park - Medical Center

2.5 out of 5
2364 South Loop W Houston TX
$59 nightly
The price is $69 total per night
$69 total
Jul 19 - Jul 20
Total with taxes and fees
Free Cancellation
With a stay at Quality Inn & Suites NRG Park - Medical Center in Houston (South Main), you'll be within a 5-minute drive of NRG Stadium and NRG Park.
Holiday Inn Houston S - Nrg Area - Medical Center by IHG

Holiday Inn Houston S - Nrg Area - Medical Center by IHG

3 out of 5
8111 Kirby Dr Houston TX
$112 nightly
The price is $131 total per night
$131 total
Jul 21 - Jul 22
Total with taxes and fees
Located in Houston (Astrodome), Holiday Inn Houston S - Nrg Area - Medical Center by IHG is within a 15-minute walk of NRG Stadium and NRG Park.
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
$122 nightly
The price is $143 total per night
$143 total
Jul 5 - Jul 6
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at DoubleTree by Hilton Houston Medical Center Hotel & Suites, you'll be centrally located in Houston, a short 8-minute walk from Texas Children's Hospital and 12 minutes by foot from MD Anderson Cancer Center.
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South Houston TX
$154 nightly
The price is $180 total per night
$180 total
Jul 10 - Jul 11
Total with taxes and fees
With a stay at The Royal Sonesta Houston Galleria in Houston (The Galleria), you'll be a 1-minute drive from Westheimer Road and 10 minutes from MD Anderson Cancer Center.
Homewood Suites by Hilton Houston Near the Galleria

Homewood Suites by Hilton Houston Near the Galleria

3 out of 5
2950 Sage Rd Houston TX
$98 nightly
The price is $115 total per night
$115 total
Jul 14 - Jul 15
Total with taxes and fees
With a stay at Homewood Suites by Hilton Houston Near the Galleria in Houston (Greater Uptown), you'll be a 1-minute drive from Westheimer Road and 8 minutes from Rice University.
Sonesta ES Suites Houston Galleria

Sonesta ES Suites Houston Galleria

3 out of 5
5190 Hidalgo St Houston TX
$119 nightly
The price is $139 total per night
$139 total
Jun 21 - Jun 22
Total with taxes and fees
Located in Houston (The Galleria), Sonesta ES Suites Houston Galleria is within a 15-minute drive of Houston Zoo and MD Anderson Cancer Center.
Crowne Plaza Houston Med Ctr-Galleria Area by IHG

Crowne Plaza Houston Med Ctr-Galleria Area by IHG

3.5 out of 5
2712 Southwest Fwy Houston TX
$70 nightly
The price is $82 total per night
$82 total
Jul 6 - Jul 7
Total with taxes and fees
Free Cancellation
A stay at Crowne Plaza Houston Med Ctr-Galleria Area by IHG places you in the heart of Houston, within a 10-minute drive of Children's Museum of Houston and Houston Natural Science Museum.
The Chifley Houston, Tapestry Collection by Hilton

The Chifley Houston, Tapestry Collection by Hilton

4 out of 5
2400 West Loop S Houston TX
$135 nightly
The price is $158 total per night
$158 total
Jul 19 - Jul 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at The Chifley Houston, Tapestry Collection by Hilton in Houston (The Galleria), you'll be steps from Westheimer Road and a 3-minute drive from Memorial Park.
Aloft by Marriott Houston by the Galleria

Aloft by Marriott Houston by the Galleria

3 out of 5
5415 Westheimer Road Houston TX
$129 nightly
The price is $151 total per night
$151 total
Jul 12 - Jul 13
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Aloft by Marriott Houston by the Galleria, you'll be centrally located in Houston, within a 15-minute drive of MD Anderson Cancer Center and Toyota Center.
America's Inn - Houston

America's Inn - Houston

2 out of 5
8201 SW Freeway Houston TX
$79 nightly
The price is $93 total per night
$93 total
Jun 21 - Jun 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at America's Inn - Houston in Houston (Braeburn), you'll be within a 15-minute drive of NRG Stadium and MD Anderson Cancer Center.
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
$100 nightly
The price is $117 total per night
$117 total
Jul 5 - Jul 6
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Hilton Houston Plaza/Medical Center, you'll be centrally located in Houston, within a 5-minute drive of MD Anderson Cancer Center and NRG Stadium.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southwest Houston hotels essential information

Accommodation
1,339 hotels
Lowest Price
$69
Highest Price
$180
Popular hotels
Comfort Inn & Suites Southwest Fwy at Westpark, Quality Inn & Suites NRG Park - Medical Center, Holiday Inn Houston S - Nrg Area - Medical Center by IHG, DoubleTree by Hilton Houston Medical Center Hotel & Suites, The Royal Sonesta Houston Galleria, Homewood Suites by Hilton Houston Near the Galleria, Sonesta ES Suites Houston Galleria, Crowne Plaza Houston Med Ctr-Galleria Area by IHG, The Chifley Houston, Tapestry Collection by Hilton, Aloft by Marriott Houston by the Galleria, America's Inn - Houston, Hilton Houston Plaza/Medical Center

Most Recent Southwest Houston Hotel Reviews

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

5 out of 5
Posted 1 hour ago
CheapTickets Verified Review
"Hotel is conveniently located to the medical center , museum and rice village. Staff is professional, friendly, and accommodating to guest needs. Floors/rooms appear to be recently updated. Plenty of sitting space in lobby and bright areas to work. Bar/ food service in both lobby and outdoor pool area . Market in lobby has takeout food and delicious snack and dessert choices. One minor downside is a narrow parking garage shared with another business but elevator is convienet to the lobby once you find a spot. A scannable parking pass is provided for easy in and out. Take those corners slowly and you should be fine. We will be back!"
A verified traveler stayed at Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical Center

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