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Featured Southwest Houston Hotels with Air Conditioning

Comfort Inn & Suites Southwest Fwy at Westpark
6687 Southwest Fwy Houston TX
$64 nightly
The price is $75 total per night
$75 total
Dec 16 - Dec 17
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Comfort Inn & Suites Southwest Fwy at Westpark places you in the heart of Houston, a 3-minute drive from Houston Baptist University and 6 minutes from Lakewood Church.
Pool
Breakfast included

Quality Inn & Suites NRG Park - Medical Center
2364 South Loop W Houston TX
$55 nightly
The price is $65 total per night
$65 total
Dec 28 - Dec 29
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Quality Inn & Suites NRG Park - Medical Center in Houston (South Main), you'll be a 3-minute drive from NRG Stadium and 6 minutes from MD Anderson Cancer Center.
Pool
Breakfast included

Holiday Inn Houston S - Nrg Area - Medical Center by IHG
8111 Kirby Dr Houston TX
$108 nightly
The price is $126 total per night
$126 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
Free Cancellation
Located in Houston (Astrodome), Holiday Inn Houston S - Nrg Area - Medical Center by IHG is within a 15-minute walk of NRG Stadium and NRG Park.
Pool
Free WiFi

DoubleTree by Hilton Houston Medical Center Hotel & Suites
6800 Main Street Houston TX
$88 nightly
The price is $103 total per night
$103 total
Jan 15 - Jan 16, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at DoubleTree by Hilton Houston Medical Center Hotel & Suites, you'll be centrally located in Houston, a 7-minute walk from Texas Children's Hospital and 12 minutes by foot from MD Anderson Cancer Center.
Pool
Pet friendly

The Royal Sonesta Houston Galleria
2222 West Loop South Houston TX
$111 nightly
The price is $130 total per night
$130 total
Dec 18 - Dec 19
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at The Royal Sonesta Houston Galleria in Houston (The Galleria), you'll be a 3-minute drive from Westheimer Road and 7 minutes from Rice University.
Pool
Pet friendly

Homewood Suites by Hilton Houston Near the Galleria
2950 Sage Rd Houston TX
$100 nightly
The price is $117 total per night
$117 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Homewood Suites by Hilton Houston Near the Galleria in Houston (Greater Uptown), you'll be a 1-minute drive from Westheimer Road and 8 minutes from Rice University.
Pool
Breakfast included

Sonesta ES Suites Houston Galleria
5190 Hidalgo St Houston TX
$109 nightly
The price is $127 total per night
$127 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Houston (The Galleria), Sonesta ES Suites Houston Galleria is within a 15-minute drive of Houston Zoo and MD Anderson Cancer Center.
Pool
Breakfast included

Crowne Plaza Houston Med Ctr-Galleria Area by IHG
2712 Southwest Fwy Houston TX
$65 nightly
The price is $76 total per night
$76 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
Free Cancellation
A stay at Crowne Plaza Houston Med Ctr-Galleria Area by IHG places you in the heart of Houston, within a 10-minute drive of Children's Museum of Houston and Houston Natural Science Museum.
Pool
Free WiFi

The Chifley Houston, Tapestry Collection by Hilton
2400 West Loop S Houston TX
$93 nightly
The price is $108 total per night
$108 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at The Chifley Houston, Tapestry Collection by Hilton in Houston (The Galleria), you'll be steps from Westheimer Road and a 3-minute drive from Memorial Park.
Pool
Pet friendly

Aloft Houston by the Galleria
5415 Westheimer Road Houston TX
$109 nightly
The price is $128 total per night
$128 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Aloft Houston by the Galleria, you'll be centrally located in Houston, a 1-minute drive from Westheimer Road and 8 minutes from Rice University.
Pool
Pet friendly

America's Inn - Houston
8201 SW Freeway Houston TX
$73 nightly
The price is $85 total per night
$85 total
Jan 15 - Jan 16, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at America's Inn - Houston in Houston (Braeburn), you'll be within a 15-minute drive of Rice University and NRG Stadium.
Pool
Parking included

Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
$89 nightly
The price is $105 total per night
$105 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Hilton Houston Plaza/Medical Center, you'll be centrally located in Houston, within a 5-minute drive of MD Anderson Cancer Center and Rice University.
Pool
Free WiFi
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Southwest Houston hotels essential information
Accommodation | 1,353 hotels |
|---|---|
Lowest Price | $65 |
Highest Price | $130 |
Popular hotels | Comfort Inn & Suites Southwest Fwy at Westpark, Quality Inn & Suites NRG Park - Medical Center, Holiday Inn Houston S - Nrg Area - Medical Center by IHG, DoubleTree by Hilton Houston Medical Center Hotel & Suites, The Royal Sonesta Houston Galleria, Homewood Suites by Hilton Houston Near the Galleria, Sonesta ES Suites Houston Galleria, Crowne Plaza Houston Med Ctr-Galleria Area by IHG, The Chifley Houston, Tapestry Collection by Hilton, Aloft Houston by the Galleria, America's Inn - Houston, Hilton Houston Plaza/Medical Center |
Most Recent Southwest Houston Hotel Reviews

The Westin Oaks Houston at the Galleria
5 out of 5
Posted 12 hours ago
CheapTickets Verified Review
"The room was large, beautifully decorated, comfortable mattress and pillows and very clean. We live in Houston and stayed at the Westin for a week while having work done in our house.
The hotel was great and it was so nice to be connected to the Galleria for shopping and so many restaurants. The elevator system is very good and security is excellent. Self parking in the garage is free. The gym is nice and has 4 Pelotons."
A verified traveler stayed at The Westin Oaks Houston at the Galleria
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