Compare Cheap Hotels in Medical Center District Texas
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Cheap Medical Center District Hotels
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
$89 nightly
The price is $105 total per night
$105 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.43 mi from Medical Center District
With a stay at La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW in San Antonio (Medical Center District), you'll be a 4-minute drive from University of Texas Health and Science Center at San Antonio and 10 minutes from River Walk.
Pool
Hot Tub
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
$93 nightly
The price is $110 total per night
$110 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.79 mi from Medical Center District
With a stay at San Antonio Marriott Northwest Medical Center in San Antonio (Medical Center District), you'll be within a 10-minute drive of North Star Mall and The Rim Shopping Center.
Pool
Pet friendly
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
$84 nightly
The price is $99 total per night
$99 total
Dec 24 - Dec 25
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.92 mi from Medical Center District
Located in San Antonio (Medical Center District), Courtyard by Marriott Medical Center San Antonio is within a 10-minute drive of North Star Mall and The Rim Shopping Center.
Pool
Pet friendly
Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
$132 nightly
The price is $155 total per night
$155 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
7.52 mi from Medical Center District
With a stay at Hotel Valencia Riverwalk, you'll be centrally located in San Antonio, steps from San Antonio River and River Walk.
Spa
Pet friendly
Riverwalk Plaza
100 Villita Street San Antonio TX
$99 nightly
The price is $117 total per night
$117 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
7.64 mi from Medical Center District
With a stay at Riverwalk Plaza, you'll be centrally located in San Antonio, steps from San Antonio River and 3 minutes by foot from River Walk.
Pool
Free WiFi
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
303 Blum Street San Antonio TX
$89 nightly
The price is $105 total per night
$105 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
8.05 mi from Medical Center District
With a stay at La Quinta Inn & Suites by Wyndham San Antonio Riverwalk, you'll be centrally located in San Antonio, steps from Shops at Rivercenter and within a 10-minute walk of Henry B. González Convention Center.
Pool
Hot Tub
Hyatt Vacation Club at Wild Oak Ranch, San Antonio
9700 West Military Drive San Antonio TX
$106 nightly
The price is $125 total per night
$125 total
Jan 19 - Jan 20, 2026
Total with taxes and fees
Free Cancellation
7.01 mi from Medical Center District
Located in San Antonio (Far West Side), Hyatt Vacation Club at Wild Oak Ranch, San Antonio is within a 10-minute drive of Aquatica San Antonio Waterpark and Ingram Park Mall.
Pool
Hot Tub
Menger Hotel
204 Alamo Plaza San Antonio TX
$92 nightly
The price is $109 total per night
$109 total
Dec 28 - Dec 29
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
7.82 mi from Medical Center District
With a stay at Menger Hotel, you'll be centrally located in San Antonio, steps from Alamo and Ripley's Believe It or Not!.
Pool
Free WiFi
Sonesta ES Suites San Antonio Downtown Alamo Plaza
425 Bonham San Antonio TX
$78 nightly
The price is $92 total per night
$92 total
Dec 23 - Dec 24
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
7.84 mi from Medical Center District
Sonesta ES Suites San Antonio Downtown Alamo Plaza is centrally located in San Antonio, a 4-minute walk from Shops at Rivercenter and 6 minutes by foot from Alamo.
Pool
Breakfast included
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
$120 nightly
The price is $142 total per night
$142 total
Dec 24 - Dec 25
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
7.63 mi from Medical Center District
A stay at Drury Plaza Hotel San Antonio Riverwalk places you in the heart of San Antonio, steps from River Walk and San Antonio River.
Pool
Hot Tub
La Quinta Inn & Suites by Wyndham San Antonio Downtown
100 W. Cesar Chavez Blvd San Antonio TX
$81 nightly
The price is $96 total per night
$96 total
Jan 18 - Jan 19, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
7.66 mi from Medical Center District
A stay at La Quinta Inn & Suites by Wyndham San Antonio Downtown places you in the heart of San Antonio, within a 10-minute walk of San Antonio River and Market Square.
Pool
Breakfast included
Hotel Contessa
306 W Market Street San Antonio TX
$145 nightly
The price is $171 total per night
$171 total
Dec 23 - Dec 24
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
7.77 mi from Medical Center District
A stay at Hotel Contessa places you in the heart of San Antonio, within a 5-minute walk of Shops at Rivercenter and River Walk.
Pool
Hot Tub
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Medical Center District hotels essential information
Accommodation | 4,716 hotels |
|---|---|
Lowest Price | $92 |
Highest Price | $171 |
Popular hotels | La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW, San Antonio Marriott Northwest Medical Center, Courtyard by Marriott Medical Center San Antonio, Hotel Valencia Riverwalk, Riverwalk Plaza, La Quinta Inn & Suites by Wyndham San Antonio Riverwalk, Hyatt Vacation Club at Wild Oak Ranch, San Antonio, Menger Hotel, Sonesta ES Suites San Antonio Downtown Alamo Plaza, Drury Plaza Hotel San Antonio Riverwalk, La Quinta Inn & Suites by Wyndham San Antonio Downtown, Hotel Contessa |
Most Recent Medical Center District Hotel Reviews
La Quinta Inn & Suites by Wyndham San Antonio Downtown
5 out of 5
Posted 1 day ago
CheapTickets Verified Review
"Near the theater "
A verified traveler stayed at La Quinta Inn & Suites by Wyndham San Antonio Downtown
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