Compare Cheap Hotels Near Mayo Clinic Minnesota
Secret Bargains - Save an extra 10% or more on select hotels
Get more for your budget and save up to 50% off select Secret Bargain hotels
Get even more value with CheapTickets Price Guarantee!
Change your flight without a fee on select flights
Cheap Mayo Clinic Hotels
Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
$149 nightly
The price is $172 total per night
$172 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.08 mi from Mayo Clinic
A stay at Kahler Grand Hotel places you in the heart of Rochester, within a 5-minute walk of Mayo Clinic and University of Minnesota-Rochester.
Pool
Hot Tub
Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
$155 nightly
The price is $178 total per night
$178 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.13 mi from Mayo Clinic
Kahler Inn and Suites - Mayo Clinic Area is centrally located in Rochester, a 3-minute walk from Mayo Clinic and 7 minutes by foot from University of Minnesota-Rochester.
Pool
Breakfast included
Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway Rochester MN
$80 nightly
The price is $92 total per night
$92 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Free Cancellation
0.21 mi from Mayo Clinic
With a stay at Hotel Indigo Rochester – Mayo Clinic Area by IHG, you'll be centrally located in Rochester, steps from University of Minnesota-Rochester and within a 10-minute walk of Mayo Park.
Pet friendly
Free WiFi
Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
$129 nightly
The price is $149 total per night
$149 total
Dec 20 - Dec 21
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.31 mi from Mayo Clinic
With a stay at Hyatt House Rochester/Mayo Clinic Area, you'll be centrally located in Rochester, within a 10-minute walk of University of Minnesota-Rochester and Mayo Civic Center.
Pool
Hot Tub
Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
$80 nightly
The price is $92 total per night
$92 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.98 mi from Mayo Clinic
With a stay at Med City Inn & Suites - Mayo Clinic Area, you'll be centrally located in Rochester, within a 5-minute drive of Mayo Clinic and Mayo Clinic Hospital - Saint Marys Campus.
Pool
Hot Tub
Brentwood Inn & Suites
123 Fourth Ave. NW Rochester MN
$125 nightly
The price is $144 total per night
$144 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.19 mi from Mayo Clinic
Brentwood Inn & Suites is centrally located in Rochester, a 4-minute walk from Mayo Clinic and 8 minutes by foot from University of Minnesota-Rochester.
Breakfast included
Free WiFi
Hampton Inn Rochester-South
1755 S Broadway Rochester MN
$82 nightly
The price is $95 total per night
$95 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.8 mi from Mayo Clinic
With a stay at Hampton Inn Rochester-South in Rochester, you'll be within a 5-minute drive of Mayo Clinic and Mayo Clinic Hospital - Saint Marys Campus.
Pool
Hot Tub
AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S Rochester MN
$73 nightly
The price is $84 total per night
$84 total
Dec 26 - Dec 27
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.6 mi from Mayo Clinic
When you stay at AmericInn by Wyndham Rochester Near Mayo Clinic in Rochester, you'll be in a shopping district, within a 5-minute drive of Olmsted County Fairgrounds and Apache Mall.
Pool
Hot Tub
EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW Rochester MN
$99 nightly
The price is $114 total per night
$114 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
0.62 mi from Mayo Clinic
With a stay at EVEN Hotel Rochester - Mayo Clinic Area by IHG in Rochester (Kutzky Park), you'll be steps from Mayo Clinic Hospital - Saint Marys Campus and 12 minutes by foot from Mayo Clinic.
Pool
Hot Tub
Aspen Suites
1211 2nd Street Rochester MN
$137 nightly
The price is $158 total per night
$158 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.76 mi from Mayo Clinic
With a stay at Aspen Suites, you'll be centrally located in Rochester, steps from Mayo Clinic Hospital - Saint Marys Campus and within a 5-minute drive of Mayo Clinic.
Pool
Hot Tub
The Berkman
217 14th Ave SW Rochester MN
$157 nightly
The price is $180 total per night
$180 total
Dec 24 - Dec 25
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.88 mi from Mayo Clinic
Located in Rochester (Folwell), The Berkman is steps from Mayo Clinic Hospital - Saint Marys Campus and a 2-minute drive from Mayo Clinic.
Pool
Kitchen
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
1125 2nd St Sw Rochester MN
$94 nightly
The price is $108 total per night
$108 total
Dec 26 - Dec 27
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.67 mi from Mayo Clinic
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys is centrally located in Rochester, a 4-minute walk from Mayo Clinic Hospital - Saint Marys Campus and 13 minutes by foot from Mayo Clinic.
Pool
Hot Tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Often, one of the most difficult things about booking a hotel is finding the best time to go. The cost of staying in hotels in could vary significantly, depending on the time of the year chosen. If you would like to figure out the most suitable time to take a trip then using CheapTickets could be the best option for you. We will be able to provide information on hotels in to ensure that you get the best deal possible. So if you are looking for a booking website that will streamline the process and offer good prices, then log in and get booking.
Mayo Clinic hotels essential information
Accommodation | 424 hotels |
|---|---|
Lowest Price | $84 |
Highest Price | $180 |
Popular hotels | Kahler Grand Hotel, Kahler Inn and Suites - Mayo Clinic Area, Hotel Indigo Rochester – Mayo Clinic Area by IHG, Hyatt House Rochester/Mayo Clinic Area, Med City Inn & Suites - Mayo Clinic Area, Brentwood Inn & Suites, Hampton Inn Rochester-South, AmericInn by Wyndham Rochester Near Mayo Clinic, EVEN Hotel Rochester - Mayo Clinic Area by IHG, Aspen Suites, The Berkman, SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys |
Most Recent Mayo Clinic Hotel Reviews
Hampton Inn Rochester-South
5 out of 5
Posted 2 days ago
CheapTickets Verified Review
"Very clean room and hotel. Breakfast was very good."
A verified traveler from Rice Lake stayed at Hampton Inn Rochester-South
Top 20 Mayo Clinic Hotels
Hotels Near Mayo Clinic
Cities near Mayo Clinic
More to Explore in Mayo Clinic
Top Picks
Hotels
- OYORooms Hotels in Mangaldai
- 5 Star Hotels in Orlando
- Hotels in Phuntsholing
- Hotels in Dhenkanal
- Hotels in Northampton
- Hotels near Gerald R. Ford Intl.
- Hotels in Williamsport
- Hotels in Florida Panhandle
- Ace Hotel Brooklyn
- LaQuintaInnSuites Hotels in Concord
- Hotels in Godda
- Hotels in Summerland Key
- Hotels near Santa Paula
- Hotels near University of Pennsylvania
- Hotels in Oak Island
- Hotels near McDonald Observatory
Flights