Compare Cheap Hotels in Downtown Rochester Minnesota

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Cheap Downtown Rochester Hotels

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN

$149 nightly

$172 total

Dec 14 - Dec 15

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

0.08 mi from Downtown Rochester

A stay at Kahler Grand Hotel places you in the heart of Rochester, within a 5-minute walk of Mayo Clinic and University of Minnesota-Rochester.

Pool

Hot Tub

Kahler Inn and Suites - Mayo Clinic Area

9 3rd Ave Nw Rochester MN

$133 nightly

$153 total

Dec 27 - Dec 28

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

0.18 mi from Downtown Rochester

Kahler Inn and Suites - Mayo Clinic Area is centrally located in Rochester, a 3-minute walk from Mayo Clinic and 7 minutes by foot from University of Minnesota-Rochester.

Pool

Breakfast included

Hyatt House Rochester/Mayo Clinic Area

110 Civic Center Drive NW Rochester MN

$129 nightly

$149 total

Dec 20 - Dec 21

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

0.31 mi from Downtown Rochester

With a stay at Hyatt House Rochester/Mayo Clinic Area, you'll be centrally located in Rochester, within a 10-minute walk of University of Minnesota-Rochester and Mayo Civic Center.

Pool

Hot Tub

Hotel Indigo Rochester – Mayo Clinic Area by IHG

220 S Broadway Rochester MN

$76 nightly

$88 total

Dec 26 - Dec 27

Total with taxes and fees

Free Cancellation

0.14 mi from Downtown Rochester

With a stay at Hotel Indigo Rochester – Mayo Clinic Area by IHG, you'll be centrally located in Rochester, steps from University of Minnesota-Rochester and within a 10-minute walk of Mayo Park.

Pet friendly

Free WiFi

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN

$125 nightly

$144 total

Dec 14 - Dec 15

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

0.24 mi from Downtown Rochester

Brentwood Inn & Suites is centrally located in Rochester, a 4-minute walk from Mayo Clinic and 8 minutes by foot from University of Minnesota-Rochester.

Breakfast included

Free WiFi

Marriott Rochester Mayo Clinic

101 1st Ave Sw Rochester MN

$259 nightly

$298 total

Jan 13 - Jan 14, 2026

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

0.03 mi from Downtown Rochester

A stay at Marriott Rochester Mayo Clinic places you in the heart of Rochester, just a 5-minute walk from Mayo Clinic and within a 5-minute drive of Mayo Clinic Hospital - Saint Marys Campus.

Pool

Hot Tub

Hilton Garden Inn Rochester Downtown, MN

225 S Broadway Rochester MN

$107 nightly

$123 total

Dec 20 - Dec 21

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

0.12 mi from Downtown Rochester

With a stay at Hilton Garden Inn Rochester Downtown, MN, you'll be centrally located in Rochester, within a 5-minute drive of Mayo Clinic and Mayo Clinic Hospital - Saint Marys Campus.

Pool

Hot Tub

Hilton Rochester Mayo Clinic Area

10 East Center Street Rochester MN

$171 nightly

$197 total

Dec 20 - Dec 21

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

0.13 mi from Downtown Rochester

With a stay at Hilton Rochester Mayo Clinic Area, you'll be centrally located in Rochester, within a 5-minute drive of Mayo Clinic and Mayo Clinic Hospital - Saint Marys Campus.

Pool

Hot Tub

TownePlace Suites by Marriott Rochester Mayo Clinic Area

601 2ND STREET SW Rochester MN

$118 nightly

$136 total

Dec 26 - Dec 27

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

0.31 mi from Downtown Rochester

Located in Rochester (Downtown Rochester), TownePlace Suites by Marriott Rochester Mayo Clinic Area is a 5-minute walk from Mayo Clinic and 9 minutes by foot from University of Minnesota-Rochester.

Breakfast included

Free WiFi

Residence Inn by Marriott Rochester Mayo Clinic Area

441 W Center St Nw Rochester MN

$189 nightly

$218 total

Jan 13 - Jan 14, 2026

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

0.23 mi from Downtown Rochester

A stay at Residence Inn by Marriott Rochester Mayo Clinic Area places you in the heart of Rochester, just a 3-minute walk from Mayo Clinic and within a 5-minute drive of Mayo Clinic Hospital - Saint Marys Campus.

Breakfast included

Pet friendly

Broadway Plaza, Trademark Collection by Wyndham

15 1st Street Southeast Rochester MN

$239 nightly

$275 total

Jan 13 - Jan 14, 2026

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

0.12 mi from Downtown Rochester

With a stay at Broadway Plaza, Trademark Collection by Wyndham, you'll be centrally located in Rochester, steps from University of Minnesota-Rochester and Shops University Square.

Pool

Hot Tub

The Towers At Kahler Grand Hotel

20 2nd Ave SW Rochester MN

Free Cancellation

Reserve now, pay when you stay

0.07 mi from Downtown Rochester

A stay at The Towers At Kahler Grand Hotel places you in the heart of Rochester, just a 4-minute walk from Mayo Clinic and within a 5-minute drive of Mayo Clinic Hospital - Saint Marys Campus.

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Downtown Rochester hotels essential information

Accommodation	378 hotels
Lowest Price	$88
Highest Price	$298
Popular hotels	Kahler Grand Hotel, Kahler Inn and Suites - Mayo Clinic Area, Hyatt House Rochester/Mayo Clinic Area, Hotel Indigo Rochester – Mayo Clinic Area by IHG, Brentwood Inn & Suites, Marriott Rochester Mayo Clinic, Hilton Garden Inn Rochester Downtown, MN, Hilton Rochester Mayo Clinic Area, TownePlace Suites by Marriott Rochester Mayo Clinic Area, Residence Inn by Marriott Rochester Mayo Clinic Area, Broadway Plaza, Trademark Collection by Wyndham, The Towers At Kahler Grand Hotel

Most Recent Downtown Rochester Hotel Reviews

Kahler Inn and Suites - Mayo Clinic Area

5 out of 5

Posted 1 day ago

CheapTickets Verified Review

"Clean rooms & public areas in a great location , friendly staff, comfortable beds, nice breakfast choice connected to lower level sub walk to all Mayo bldgs & several bars /eateries. "

A verified traveler stayed at Kahler Inn and Suites - Mayo Clinic Area