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Best Western in La Mesa
Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
$125 nightly
The price is $144 total per night
$144 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
10.52 mi from city center
A stay at Sheraton San Diego Resort places you in the heart of San Diego, just a 4-minute walk from Naval Base Coronado and within a 5-minute drive of Port of San Diego.
Lafayette Hotel & Club
2223 El Cajon Blvd San Diego CA
$229 nightly
The price is $263 total per night
$263 total
Dec 29 - Dec 30
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
6.89 mi from city center
With a stay at Lafayette Hotel & Club in San Diego (University Heights), you'll be within a 5-minute drive of San Diego Zoo and Hotel Circle.
Pool
Pet friendly
The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
$103 nightly
The price is $120 total per night
$120 total
Dec 28 - Dec 29
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
8.73 mi from city center
A stay at The DEXTRO Little Italy, BW Premier Collection places you in the heart of San Diego, within a 5-minute drive of USS Midway Museum and Balboa Park.
Pool
Free WiFi
Legacy Resort Hotel & Spa
875 Hotel Circle South San Diego CA
$152 nightly
The price is $175 total per night
$175 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
8.57 mi from city center
With a stay at Legacy Resort Hotel & Spa in San Diego (Mission Valley), you'll be a 4-minute walk from Hotel Circle and within a 5-minute drive of Old Town San Diego State Park.
Pool
Hot Tub
Hard Rock Hotel San Diego
207 5th Ave San Diego CA
$210 nightly
The price is $243 total per night
$243 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
8.95 mi from city center
With a stay at Hard Rock Hotel San Diego, you'll be centrally located in San Diego, steps from Petco Park and 3 minutes by foot from San Diego Convention Center.
Pool
Free WiFi
Best Western Plus Marina Gateway Hotel
800 Bay Marina Dr National City CA
$107 nightly
The price is $118 total per night
$118 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
9 mi from city center
Located in National City, Best Western Plus Marina Gateway Hotel is in the historical district, within a 10-minute drive of San Diego Convention Center and Balboa Park.
Pool
Hot Tub
San Diego Marriott La Jolla
4240 La Jolla Village Dr La Jolla CA
$155 nightly
The price is $178 total per night
$178 total
Jan 9 - Jan 10, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
13.36 mi from city center
With a stay at San Diego Marriott La Jolla in La Jolla (University City), you'll be a 1-minute drive from University of California, San Diego and 9 minutes from Mission Bay.
Courtyard by Marriott San Diego Downtown Little Italy
1646 Front St San Diego CA
$110 nightly
The price is $128 total per night
$128 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
8.83 mi from city center
In the heart of San Diego, Courtyard by Marriott San Diego Downtown Little Italy is within a 5-minute drive of San Diego Convention Center and Seaport Village.
Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
$129 nightly
The price is $148 total per night
$148 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
12.24 mi from city center
Located in San Diego (Point Loma), Bay Club Hotel & Marina is within a 10-minute drive of Old Town San Diego State Park and USS Midway Museum.
Pool
Hot Tub
Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
$160 nightly
The price is $186 total per night
$186 total
Dec 16 - Dec 17
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
9.31 mi from city center
In the heart of San Diego, Wyndham San Diego Bayside is within a 5-minute drive of USS Midway Museum and San Diego Convention Center.
Pool
Free airport shuttle
Hilton San Diego Mission Valley
901 Camino Del Rio S San Diego CA
$118 nightly
The price is $136 total per night
$136 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
7.75 mi from city center
A stay at Hilton San Diego Mission Valley places you in the heart of San Diego, a 3-minute drive from Hotel Circle and 6 minutes from Mission Bay.
Embassy Suites by Hilton San Diego La Jolla
4550 La Jolla Village Dr San Diego CA
$151 nightly
The price is $174 total per night
$174 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
13.08 mi from city center
Located in San Diego (University City), Embassy Suites by Hilton San Diego La Jolla is a 3-minute walk from Westfield UTC and 13 minutes by foot from University of California, San Diego.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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La Mesa hotels essential information
Accommodation | 8,366 hotels |
|---|---|
Lowest Price | $118 |
Highest Price | $263 |
Popular hotels | Sheraton San Diego Resort, Lafayette Hotel & Club, The DEXTRO Little Italy, BW Premier Collection, Legacy Resort Hotel & Spa, Hard Rock Hotel San Diego, Best Western Plus Marina Gateway Hotel, San Diego Marriott La Jolla, Courtyard by Marriott San Diego Downtown Little Italy, Bay Club Hotel & Marina, Wyndham San Diego Bayside, Hilton San Diego Mission Valley, Embassy Suites by Hilton San Diego La Jolla |
Most Recent La Mesa Hotel Reviews
Best Western Plus Marina Gateway Hotel
5 out of 5
Posted 2 days ago
CheapTickets Verified Review
"Room was spotless. Staff were really nice."
A verified traveler stayed at Best Western Plus Marina Gateway Hotel
