Compare Business Hotels in Downtown St. Louis

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Featured Downtown St. Louis Business Hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
$95 nightly
The price is $111 total per night
$111 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Hyatt Regency St. Louis at The Arch places you in the heart of St. Louis, within a 10-minute walk of Gateway Arch and Busch Stadium.
Pet friendly
Free WiFi
City Place St. Louis Downtown

City Place St. Louis Downtown

2.5 out of 5
200 N 4Th Street St. Louis MO
A stay at City Place St. Louis Downtown places you in the heart of St. Louis, within a 10-minute walk of Gateway Arch and Dome at America’s Center.
Pool
Parking included
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
$101 nightly
The price is $120 total per night
$120 total
Dec 8 - Dec 9
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel is centrally located in St. Louis, a 3-minute walk from America's Center Convention Complex and 6 minutes by foot from Dome at America’s Center.
Pet friendly
Free WiFi
Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

4 out of 5
400 Olive St St. Louis MO
$103 nightly
The price is $122 total per night
$122 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Hilton Pennywell St. Louis at the Arch places you in the heart of St. Louis, within a 10-minute walk of Gateway Arch and Dome at America’s Center.
Pet friendly
Restaurant
OYO Hotel St. Louis Downtown City Center MO

OYO Hotel St. Louis Downtown City Center MO

3.5 out of 5
400 S 14th St St. Louis MO
With a stay at OYO Hotel St. Louis Downtown City Center MO, you'll be centrally located in St. Louis, just a 4-minute walk from Enterprise Center and 14 minutes by foot from St. Louis Union Station.
Pet friendly
Free WiFi
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$135 nightly
The price is $158 total per night
$158 total
Dec 9 - Dec 10
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Drury Plaza Hotel St. Louis at the Arch, you'll be centrally located in St. Louis, just a 5-minute walk from Gateway Arch and 6 minutes by foot from Busch Stadium.
Pool
Hot Tub
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

4 out of 5
1820 Market Street St. Louis MO
$142 nightly
The price is $169 total per night
$169 total
Dec 11 - Dec 12
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at St. Louis Union Station Hotel, Curio Collection by Hilton places you in the heart of St. Louis, within a 5-minute walk of St. Louis Aquarium at Union Station and St. Louis Union Station Mini Golf.
Pool
Pet friendly
HoteLumiere at the Arch - A Caesars Rewards Destination

HoteLumiere at the Arch - A Caesars Rewards Destination

4 out of 5
999 N. 2nd St. St. Louis MO
$130 nightly
The price is $152 total per night
$152 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in St. Louis (Downtown St. Louis), HoteLumiere at the Arch - A Caesars Rewards Destination is within a 15-minute walk of Gateway Arch and Dome at America’s Center.
Free WiFi
Restaurant
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
$94 nightly
The price is $110 total per night
$110 total
Dec 9 - Dec 10
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Pear Tree Inn St. Louis Near Union Station places you in the heart of St. Louis, within a 15-minute walk of St. Louis Union Station and Enterprise Center.
Pool
Hot Tub
Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center

3 out of 5
711 N Broadway St. Louis MO
$94 nightly
The price is $110 total per night
$110 total
Dec 9 - Dec 10
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Pear Tree Inn St. Louis Convention Center, you'll be centrally located in St. Louis, steps from Dome at America’s Center and 12 minutes by foot from Gateway Arch.
Pool
Hot Tub
Missouri Athletic Club

Missouri Athletic Club

3.5 out of 5
405 Washington Ave St. Louis MO
$169 nightly
The price is $198 total per night
$198 total
Dec 7 - Dec 8
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Missouri Athletic Club places you in the heart of St. Louis, within a 10-minute walk of Gateway Arch and Dome at America’s Center.
Free WiFi
Restaurant
Radisson Hotel St. Louis Downtown Convention Center

Radisson Hotel St. Louis Downtown Convention Center

3.5 out of 5
811 N 9th Street St. Louis MO
With a stay at Radisson Hotel St. Louis Downtown Convention Center, you'll be centrally located in St. Louis, a 6-minute walk from America's Center Convention Complex and 10 minutes by foot from Dome at America’s Center.
Pool
Free WiFi
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Downtown St. Louis hotels essential information

Accommodation
580 hotels
Lowest Price
$110
Highest Price
$198
Popular hotels
Hyatt Regency St. Louis at The Arch, City Place St. Louis Downtown, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, Hilton Pennywell St. Louis at the Arch, OYO Hotel St. Louis Downtown City Center MO, Drury Plaza Hotel St. Louis at the Arch, St. Louis Union Station Hotel, Curio Collection by Hilton, HoteLumiere at the Arch - A Caesars Rewards Destination, Pear Tree Inn St. Louis Near Union Station, Pear Tree Inn St. Louis Convention Center, Missouri Athletic Club, Radisson Hotel St. Louis Downtown Convention Center

Most Recent Downtown St. Louis Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

5 out of 5
Posted 2 days ago
CheapTickets Verified Review
"Clean rooms friendly staff and amenities"
A verified traveler stayed at Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch

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