Important: This destination may have COVID-19 travel restrictions in place, including specific restrictions for lodging. Check any national, local, and health advisories for this destination before you book.

Cheap flights from Pittsburgh (PIT) to St. Louis (STL)

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Lowest round trip fares by airline from Pittsburgh and St. Louis

Cheapest prices ($87 One Way, $217 Round Trip) found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Wed, Sep 1
PIT
Pittsburgh
STL
St. Louis
$87
Delta
Wed, Sep 1
PIT
Pittsburgh
STL
St. Louis
$87
United
Wed, Sep 1
PIT
Pittsburgh
STL
St. Louis
$101
American Airlines
Wed, Sep 1
PIT
Pittsburgh
STL
St. Louis
$103
American Airlines
Wed, Sep 1
PIT
Pittsburgh
STL
St. Louis
$107
Delta
Thu, Jun 24 - Sun, Jun 27
PIT
Pittsburgh
STL
St. Louis
$217
Spirit Airlines
Thu, Jun 24 - Sat, Jun 26
PIT
Pittsburgh
STL
St. Louis
$229
Spirit Airlines
Thu, Jun 24 - Wed, Jun 30
PIT
Pittsburgh
STL
St. Louis
$237
Spirit Airlines
Thu, Jun 24 - Sat, Jun 26
PIT
Pittsburgh
STL
St. Louis
$239
Spirit Airlines
Wed, Aug 4 - Mon, Aug 9
PIT
Pittsburgh
STL
St. Louis
$245
United

Great Deals On Cheap Hotels in St. Louis

Quality Inn St. Louis Airport Hotel

Quality Inn St. Louis Airport Hotel

2.5 out of 5
10232 Natural Bridge Rd, St. Louis, MO
The price is $79 per night from Jun 16 to Jun 16
Located in Airport Township, this hotel is within 6 mi (10 km) of St. Louis Mercantile Library, Blanche M. Touhill Performing Arts Center, and Holocaust Museum. ...
2.5/5 (2 reviews)
"Awful conditions. Stained sheets, loud neighbors, hallway smelled like marijuana."

Reviewed on Dec 31, 2018

Quality Inn St. Louis Airport Hotel
Airport Plaza Inn and Conference Center

Airport Plaza Inn and Conference Center

2.5 out of 5
4530 N Lindbergh Boulevard, Bridgeton, MO
Located in Airport Township, this hotel is 1.4 mi (2.3 km) from Payne-Gentry Historical House and within 6 mi (10 km) of Hollywood Casino Amphitheatre and St. ...
3/5 (3 reviews)
"Very nice hotel close to downtown St Louis and the zoo and six flags"

Reviewed on Jul 5, 2017

Airport Plaza Inn and Conference Center
Americas Best Value Inn St. Louis Downtown

Americas Best Value Inn St. Louis Downtown

2 out of 5
1100 Lumiere Place Boulevard, St. Louis, MO
The price is $150 per night from Jun 16 to Jun 16
Located in Downtown St. Louis, this motel is within a 10-minute walk of Lumiere Place Casino, Laclede's Landing, and Dome at America’s Center. America's Center ...
3/5 (4 reviews)
Affordable and Near Downtown Attractions
"The staff member/receptionist was excellent and extremely helpful and caring.The hotel is located one block from the best casino in St. Louis. So it was real easy to walk too. No pool, as the price reflected it with being affordable and downtown."

Reviewed on May 29, 2018

Americas Best Value Inn St. Louis Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fly From Pittsburgh to St. Louis

Origin Pittsburgh
Destination St. Louis
Number of Daily Flights 1
Earliest Flight Departure Date Jun 22
Latest Flight Departure Date Jun 22
Popular Airlines

Cheap flights from Pittsburgh to St. Louis

Are you ready to book your flight, but feeling nervous about paying too much if prices drop in a few days? Don't play the waiting game. Our Best Price Guarantee means if you see a better fare for the same flight, we'll give you the difference in CheapCash, plus $50 more in CheapCash, which you can use to save on your hotel reservation.

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Save Even More Time and Money With a St. Louis Travel Package

Once your flights are booked, why start all over again searching for a cheap hotel? Book your flight and hotel together, and save yourself more than time and energy. You'll also be able to take advantage of discounts and coupons on your St. Louis vacation that you can't get when you book flights and hotel separately.

Relax in St. Louis With Confidence and Convenience

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.