Compare Spa Resorts & Hotels in South Carolina
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Featured South Carolina Spa Resorts & Hotels
Sonesta Resort Hilton Head Island
130 Shipyard Drive Hilton Head Island SC
$194 nightly
The price is $214 total per night
$214 total
Dec 7 - Dec 8
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Sonesta Resort Hilton Head Island in Hilton Head Island (South End), you'll be within a 15-minute drive of Coligny Beach and Palmetto Dunes Beach.
Pool
Hot Tub
The Charleston Place
130 Market St Charleston SC
$492 nightly
The price is $561 total per night
$561 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at The Charleston Place in Charleston (Charleston Historic District), you'll be within a 5-minute walk of College of Charleston and Charleston City Market.
Pool
Hot Tub
Sands Ocean Club Resort
9550 Shore Dr Myrtle Beach SC
$96 nightly
The price is $106 total per night
$106 total
Dec 6 - Dec 7
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Sands Ocean Club Resort in Myrtle Beach, you'll be on the beach, a 4-minute drive from Apache Pier and 7 minutes from Barefoot Landing.
Pool
Spa
Omni Hilton Head Oceanfront Resort
23 Ocean Lane Hilton Head Island SC
$218 nightly
The price is $235 total per night
$235 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Omni Hilton Head Oceanfront Resort in Hilton Head Island (Mid Island), you'll be a 4-minute drive from The Golf Courses of Palmetto Dunes and 7 minutes from Shelter Cove Harbour.
Pool
Spa
The Westin Hilton Head Island Resort & Spa
2 Grasslawn Ave Hilton Head Island SC
$168 nightly
The price is $185 total per night
$185 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Hilton Head Island (Mid Island), The Westin Hilton Head Island Resort & Spa is within a 10-minute drive of Coastal Discovery Museum and Shelter Cove Harbour.
Pool
Hot Tub
Hilton Beachfront Resort & Spa Hilton Head Island
1 Hotel Circle Hilton Head Island SC
$173 nightly
The price is $191 total per night
$191 total
Dec 11 - Dec 12
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Hilton Beachfront Resort & Spa Hilton Head Island in Hilton Head Island (Mid Island), you'll be within a 5-minute walk of Palmetto Dunes Club and Palmetto Dunes Beach.
Pool
Spa
Harborside at Charleston Harbor Resort and Marina
20 Patriots Point Rd Mount Pleasant SC
$141 nightly
The price is $159 total per night
$159 total
Dec 8 - Dec 9
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Harborside at Charleston Harbor Resort and Marina in Mount Pleasant, you'll be on the waterfront, a 1-minute drive from Patriots Point and 9 minutes from South Carolina Aquarium.
Pool
Hot Tub
The Francis Marion Hotel
387 King St Charleston SC
$143 nightly
The price is $163 total per night
$163 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at The Francis Marion Hotel, you'll be centrally located in Charleston, steps from Marion Square and College of Charleston.
Spa
Free WiFi
Landmark Resort
1501 S Ocean Blvd Myrtle Beach SC
$96 nightly
The price is $109 total per night
$109 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
When you stay at Landmark Resort in Myrtle Beach, you'll be on the beach, within a 5-minute drive of Myrtle Beach Boardwalk and Family Kingdom Amusement Park.
Pool
Hot Tub
Isle Of Palms Condo, half block to beach, enter with combo, private entrance.
Isle of Palms SC
With a stay at this condo, you'll be centrally located in Isle of Palms, a 1-minute drive from Front Beach and 11 minutes from Wild Dunes Resort Golf Course.
Pool
Kitchen
Compass Cove Resort
2311 S. Ocean Blvd Myrtle Beach SC
$90 nightly
The price is $102 total per night
$102 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
When you stay at Compass Cove Resort in Myrtle Beach, you'll be on the beach, within a 5-minute drive of Myrtle Beach Boardwalk and Family Kingdom Amusement Park.
Pool
Hot Tub
Montage Palmetto Bluff
477 Mount Pelia Road Bluffton SC
$434 nightly
The price is $477 total per night
$477 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Montage Palmetto Bluff in Bluffton, you'll be 0.2 mi (0.3 km) from May River Golf Club at Palmetto Bluff and 10.6 mi (17.1 km) from Farmers Market of Bluffton.
Pool
Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South Carolina Spa Resorts & Hotels essential information
Spa Resorts & Hotels in South Carolina |
567 |
|---|---|
Highest price | $561 |
Cheapest price | $102 |
Total number of hotels in South Carolina | 52,448 |
Popular hotels | Sonesta Resort Hilton Head Island, The Charleston Place, Sands Ocean Club Resort, Omni Hilton Head Oceanfront Resort, The Westin Hilton Head Island Resort & Spa, Hilton Beachfront Resort & Spa Hilton Head Island, Harborside at Charleston Harbor Resort and Marina, The Francis Marion Hotel, Landmark Resort, Isle Of Palms Condo, half block to beach, enter with combo, private entrance. , Compass Cove Resort, Montage Palmetto Bluff |
Most Recent South Carolina Hotel Reviews
Sea Crest Oceanfront Resort
5 out of 5
Posted 20 hours ago
CheapTickets Verified Review
"The room was clean. The staff was nice. The only thing the beds are a little hard"
A verified traveler stayed at Sea Crest Oceanfront Resort
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