Compare Cheap Clayton Independent
Secret Bargains - Save an extra 10% or more on select hotels
Get more for your budget and save up to 50% off select Secret Bargain hotels
Get even more value with CheapTickets Price Guarantee!
Change your flight without a fee on select flights
Independent in Clayton

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
$100 nightly
The price is $116 total per night
$116 total
May 3 - May 4
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.83 mi from Clayton
With a stay at Clayton Plaza Hotel & Extended Stay in St. Louis (Clayton), you'll be within a 5-minute drive of Washington University in St. Louis and Forest Park.
Pool
Breakfast included

The Ritz-Carlton, St. Louis
100 Carondelet Plaza St. Louis MO
$499 nightly
The price is $583 total per night
$583 total
Apr 26 - Apr 27
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.59 mi from Clayton
With a stay at The Ritz-Carlton, St. Louis, you'll be centrally located in St. Louis, within a 5-minute drive of Washington University in St. Louis and Forest Park.
Spa
Pet friendly

AC Hotel St. Louis Clayton
227 South Central Ave St. Louis MO
$135 nightly
The price is $158 total per night
$158 total
May 10 - May 11
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.88 mi from Clayton
With a stay at AC Hotel St. Louis Clayton in St. Louis (Clayton), you'll be a 4-minute drive from Washington University in St. Louis and 7 minutes from St. Louis Zoo.

Le Méridien St. Louis Clayton
7730 Bonhomme Ave St. Louis MO
$135 nightly
The price is $159 total per night
$159 total
May 10 - May 11
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
0.75 mi from Clayton
Located in St. Louis (Clayton), Le Méridien St. Louis Clayton is within a 5-minute drive of Washington University in St. Louis and Forest Park.

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
216 N Meramec Ave St. Louis MO
$130 nightly
The price is $154 total per night
$154 total
May 7 - May 8
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.17 mi from Clayton
In the heart of St. Louis, Hampton Inn & Suites Clayton/St. Louis-Galleria Area is within a 5-minute drive of Washington University in St. Louis and Forest Park.
Pool
Breakfast included

Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
$137 nightly
The price is $161 total per night
$161 total
May 8 - May 9
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
7.42 mi from Clayton
A stay at Hyatt Regency St. Louis at The Arch places you in the heart of St. Louis, within a 10-minute walk of Gateway Arch and Busch Stadium.
Pet friendly
Free WiFi

Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
$90 nightly
The price is $106 total per night
$106 total
May 3 - May 4
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
7.13 mi from Clayton
With a stay at Pear Tree Inn St. Louis Airport, you'll be centrally located in St. Ann, within a 15-minute drive of Hollywood Casino Amphitheatre and Westport Plaza.
Pool
Breakfast included

21C Museum Hotel St Louis
1528 Locust street St. Louis MO
$156 nightly
The price is $183 total per night
$183 total
May 3 - May 4
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
6.58 mi from Clayton
A stay at 21C Museum Hotel St Louis places you in the heart of St. Louis, within a 10-minute walk of St. Louis Union Station and City Museum.
Pool
Spa

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
$162 nightly
The price is $189 total per night
$189 total
May 3 - May 4
Total with taxes and fees
7.38 mi from Clayton
A stay at Drury Plaza Hotel St. Louis at the Arch places you in the heart of St. Louis, within a 10-minute walk of Gateway Arch and Busch Stadium.
Pool
Hot Tub

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
$89 nightly
The price is $103 total per night
$103 total
May 17 - May 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
10.39 mi from Clayton
A stay at Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham places you in the heart of Fenton, within a 5-minute drive of SSM Health St. Clare Hospital - Fenton and Laumeier Sculpture Park.
Pool
Hot Tub

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
333 Washington Ave St. Louis MO
$122 nightly
The price is $143 total per night
$143 total
May 3 - May 4
Total with taxes and fees
7.45 mi from Clayton
With a stay at Hampton Inn St. Louis-Downtown (At the Gateway Arch), you'll be centrally located in St. Louis, a short 8-minute walk from Gateway Arch and 14 minutes by foot from Busch Stadium.

Live by Loews - St.Louis
799 Clark ave St. Louis MO
$159 nightly
The price is $189 total per night
$189 total
May 10 - May 11
Total with taxes and fees
7.13 mi from Clayton
With a stay at Live by Loews - St.Louis in St. Louis (Downtown St. Louis), you'll be steps from Busch Stadium and 12 minutes by foot from Gateway Arch.
Pet friendly
Free WiFi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Clayton hotels essential information
Accommodation | 1,921 hotels |
|---|---|
Lowest Price | $103 |
Highest Price | $583 |
Popular hotels | Clayton Plaza Hotel & Extended Stay, The Ritz-Carlton, St. Louis, AC Hotel St. Louis Clayton, Le Méridien St. Louis Clayton, Hampton Inn & Suites Clayton/St. Louis-Galleria Area, Hyatt Regency St. Louis at The Arch, Pear Tree Inn St. Louis Airport, 21C Museum Hotel St Louis , Drury Plaza Hotel St. Louis at the Arch, Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, Hampton Inn St. Louis-Downtown (At the Gateway Arch), Live by Loews - St.Louis |
Most Recent Clayton Hotel Reviews

Clayton Plaza Hotel & Extended Stay
3 out of 5
Posted 1 hour ago
CheapTickets Verified Review
"Beautiful hotel!! Great breakfast!! Room was small and a little noisey due to being across from parking garage and above the generator but I suppose it was a discounted room rate for Expedia! Bed was very comfy and room was dark. So the two balanced itself out!! I would stay again!!"
A verified traveler stayed at Clayton Plaza Hotel & Extended Stay
Top Picks
- Boutique Hotels in Clayton
- Hyatt Hotels in Maryland Heights
- Hotels with Suites in Brentwood
- Luxury Hotels in Clayton
- Hotels with Air Conditioning in Brentwood
- 5 Star Hotels in Clayton
- Pet Friendly Hotels in Central West End
- Town Houses in Frontenac
- Bellerive Acres Hotels
- Drury Inn & Suites Hotels in Creve Coeur
- Hotels near St. Louis Zoo
- Hotels with Pools in Frontenac
- Inns in Frontenac
- Red Roof Inn Hotels in Central West End
- La Quinta Inn & Suites Hotels in Creve Coeur
- Hotels with Restaurants in Clayton
- Motel 6 Hotels in St. Louis
- Hyatt Hotels in Fenton
- 4 Star Hotels in Creve Coeur
- Adventure Sport Hotels in Brentwood
- Hotels with Restaurants in Central West End
- 4 Star Hotels in Brentwood
- Central West End Hotels
- Drury Inn & Suites Hotels in Augusta
- Historic Hotels in Brentwood
- Arcade Hotels in Clayton
- Hotels with Suites in Central West End
- Hotels with Bars in Central West End
- Extended Stay Hotels in Kirkwood
- Condo Rentals in St. Louis County
- Drury Inn & Suites Hotels in Bridgeton
- Hotels with Free Breakfast in Brentwood
- Romantic Getaways & Hotels in Brentwood
- Hotels with Restaurants in Brentwood
- Villas in Brentwood
- Business Hotels in Brentwood
- Hotels with Balconies in Clayton
- 3 Star Hotels in Brentwood
- Hotels with an Indoor Pool in Clayton
- Hilton Hotels in Creve Coeur
- 3 Star Hotels in Central West End
- Extended Stay America Hotels in St. Charles
- Spa Resorts & in Creve Coeur
- La Quinta Inn & Suites Hotels in Central West End
- Hotels with WiFi in Brentwood
- La Quinta Inn & Suites Hotels in St. Charles
- Drury Inn & Suites Hotels in Earth City
- Oakwood Hotels in Fenton
- Hotels near Saint Louis Galleria Mall
- Hotels with Free Parking in Clayton
- Hotels near St. Louis Art Museum
- Hotels near St. Alphonsus Liguori Catholic Church
- Hyatt Hotels in Creve Coeur
- Best Western Hotels in Earth City
- Jennings Hotels
- Historic Hotels in Frontenac
- 3 Star Hotels in Clayton
- 4 Star Hotels in Central West End
- Drury Inn & Suites Hotels in Chesterfield
- Adventure Sport Hotels in Central West End
- 4 Star Hotels in Clayton
- Cheap Hotels in Brentwood
- Hyatt Hotels in Clayton
- St. Louis County Hotels
- Hillsdale Hotels
- Hotels with a Gym in Clayton
- Drury Inn & Suites Hotels in O'Fallon
- Kid Friendly Hotels in Clayton
- Oyo Rooms Hotels in Florissant
- Hotels with Pools in Brentwood
- 3 Star Hotels in Creve Coeur
- Hotels near Barnes Jewish Hospital
- Clayton Hotels
- Academy - Sherman Park Hotels
- Hotels with Balconies in Central West End
- Hotels with Shopping in Creve Coeur
- Hotels with Tennis Courts in Clayton
- Historic Hotels in Clayton
- La Quinta Inn & Suites Hotels in Downtown St. Louis
- Hotels with Balconies in Brentwood
- Hilton Hotels in Bridgeton
- Hotels with Bars in Clayton
- Pasadena Hills Hotels
- Oyo Rooms Hotels in Creve Coeur
- Cabin Rentals in St. Louis County
- B&B in Brentwood
- Hotels near Samuel Cupples House
- Oyo Rooms Hotels in St. Charles
- 5 Star Hotels in Brentwood
- Best Western Hotels in Clayton





