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21C Museum Hotel St Louis

4.5 star property

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Photo gallery for 21C Museum Hotel St Louis

Restaurant
Bar (on property)
Massages
Exterior
Exterior

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Pet friendly
  • Free WiFi
  • Air conditioning
$153
$131 nightly
$153 total
Total with taxes and fees
Feb 22 - Feb 23

Explore the area

View in a map
1528 Locust street, St. Louis, MO, 63103
  • Place, City Museum
    ‪5 min walk‬
  • Place, St. Louis Union Station
    ‪8 min walk‬
  • Place, Enterprise Center
    ‪8 min walk‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪19 min drive‬

Room options

View all photos for Deluxe Room, 1 King Bed

In-room safe, desk, laptop workspace, blackout drapes

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(84 reviews)
  • 309 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

Luxury Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout drapes

Luxury Double Room, 2 Queen Beds

9.2 out of 10
Wonderful
(24 reviews)
  • 423 sq ft
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room (Bunk Bed)

Room (Bunk Bed) | In-room safe, desk, laptop workspace, blackout drapes

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)
  • 237 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 Twin Bunk Bed

View all photos for Loft, 2 Queen Beds

Loft, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout drapes

Loft, 2 Queen Beds

8.0 out of 10
Very good
(1 review)
  • 431 sq ft
  • Sleeps 4
  • 2 Queen Beds

View all photos for Deluxe Room, Accessible (Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Deluxe Room, Accessible (Accessible)

  • 269 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (21C)

Suite, 1 King Bed (21C) | In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed (21C)

  • 1119 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (Library)

Suite, 1 King Bed (Library) | In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed (Library)

  • City view
  • 732 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Suite, 1 King Bed

Luxury Suite, 1 King Bed | In-room safe, desk, laptop workspace, blackout drapes

Luxury Suite, 1 King Bed

10.0 out of 10
Exceptional
(1 review)
  • 549 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room, 1 Double Bed, Accessible

Deluxe Room, 1 Double Bed, Accessible | In-room safe, desk, laptop workspace, blackout drapes

Deluxe Room, 1 Double Bed, Accessible

  • 388 sq ft
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Suite, 1 Double Bed, Accessible

In-room safe, desk, laptop workspace, blackout drapes

Deluxe Suite, 1 Double Bed, Accessible

  • 517 sq ft
  • Sleeps 2
  • 1 Double Bed

Similar properties

Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
  • Pet friendly
  • Free WiFi
  • Restaurant
  • Air conditioning
4.4 out of 5, Excellent, 1,219 reviews
$103 nightly
The price is $122
Feb 2 - Feb 3
Total with taxes and fees
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

About the neighborhood

St. Louis

A stay at 21C Museum Hotel St Louis places you in the heart of St. Louis, within a 10-minute walk of St. Louis Union Station and City Museum. .This luxury hotel is 0.4 mi (0.7 km) from Enterprise Center and 0.7 mi (1.1 km) from America's Center Convention Complex.

What's nearby

  • Washington Avenue Historic District - 2 min walk - 0.1 miles
  • City Museum - 5 min walk - 0.3 miles
  • St. Louis Union Station - 8 min walk - 0.4 miles
  • Enterprise Center - 8 min walk - 0.5 miles
  • St. Louis Aquarium at Union Station - 11 min walk - 0.6 miles

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • St. Louis Lambert Intl. Airport (STL) - 24 min drive

Restaurants

  • ‪Imo's Pizza Headquarters & Retail Store - ‬7 min walk
  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪White Knight Diner - ‬4 min walk
  • ‪City Museum Rooftop Cafe - ‬5 min walk
  • ‪Medina Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel with an indoor pool, 8-minute walk to St. Louis Union Station
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and safes. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries, and hair dryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include complimentary bottled water and irons/ironing boards. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool, a steam room, and a fitness center.
Guests can pamper themselves by indulging in the onsite spa services. Services include massages.
Make yourself at home in one of the 104 air-conditioned rooms featuring espresso makers and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have complimentary toiletries and hair dryers. Conveniences include phones, as well as safes and desks.
Don't miss out on the many recreational opportunities, including an indoor pool, a steam room, and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, concierge services, and a banquet hall.
Enjoy a meal at the restaurant or snacks in the coffee shop/cafe. The hotel also offers room service (during limited hours). Wrap up your day with a drink at the bar/lounge. Cooked-to-order breakfasts are available daily from 6:30 AM to 1:00 PM for a fee.
Featured amenities include a business center, dry cleaning/laundry services, and a 24-hour front desk.
Cooked-to-order breakfasts are available for a surcharge and are served each morning between 6:30 AM and 1:00 PM.
21C Museum Hotel St Louis has a restaurant on site.
Room service (during limited hours) is available.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Grab bar in shower (35 inches high)
  • Handrails in stairways (36 inches high)
  • Lever door handles
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk (36 inches high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathrobes
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs only

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 1129 out of 1580 reviews
Rating 8 - Good. 239 out of 1580 reviews
Rating 6 - Okay. 108 out of 1580 reviews
Rating 4 - Poor. 48 out of 1580 reviews
Rating 2 - Terrible. 56 out of 1580 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

Reviews

10/10 Excellent

Charles

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Loved this hotel. Nice atmosphere
Stayed 1 night in Oct 2025

10/10 Excellent

Megan

Stayed 1 night in Oct 2025

10/10 Excellent

Alexander

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Good
Stayed 1 night in Oct 2025

4/10 Poor

Ricardo

Liked: Property conditions & facilities
Disliked: Staff & service
Cancellation Service. I couldn’t make it to the room now. I was trying to cancel and this is until six A.M. when I had to do the cancellation and it’s not Aiven Six, A.M. and I didn’t check in and I Just Lose The Money.
Stayed 1 night in Oct 2025

8/10 Good

Ulric

Stayed 1 night in Oct 2025

10/10 Excellent

Karen

Stayed 1 night in Oct 2025

8/10 Good

Anne

Liked: Property conditions & facilities, room comfort
Stayed 1 night in Oct 2025

10/10 Excellent

Julian

Stayed 3 nights in Oct 2025

10/10 Excellent

Lora

Stayed 1 night in Oct 2025

8/10 Good

Akela

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
The overall set up of the room was perfect. I loved everything; from the bed sheets, robes, huge bathtub and separate walk in shower. It felt cozy yet luxurious. The staff on the other hand were very pretentious. The lobby area is extremely loud and while checking in the staff spoke in a low tone so it was very difficult to hear the information being said. When I asked for clarification on things I didn’t hear or was curious about, I got very short answers or little guidance, like I was unconvincing them. This didn’t happen with just one staff member, it was every person I encountered: vallet, checking in and at the spa. I know the hotel is supposed to be elevated, but that doesn’t mean you can’t be hospitable.
Stayed 1 night in Oct 2025

10/10 Excellent

Catherine

Traveled with partner
Liked: Cleanliness, staff & service, property conditions & facilities
Great location for an event we attended.
Stayed 1 night in Sep 2025

10/10 Excellent

CASEY

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Oct 2025

6/10 Okay

Gregg

Stayed 1 night in Oct 2025

10/10 Excellent

Brandi

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

This place was absolutely incredible. 10/10.

I have been to my fair share of hotels. Mostly higher end properties and this is now one of my favorite hotels of all time. The beauty, the art, the service, the intentionality...this place was absolutely incredible. 10/10.
Stayed 2 nights in Oct 2025

10/10 Excellent

Helen

Stayed 2 nights in Oct 2025

10/10 Excellent

Jonathan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Neat place that is a different than you average hotel. Fun experience.
Stayed 1 night in Oct 2025

10/10 Excellent

Peter

Stayed 2 nights in Sep 2025

8/10 Good

Catricia

Stayed 1 night in Oct 2025

10/10 Excellent

Vincent

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff was very kind and eager to help. Valet were quick, friendly, but very expensive considering it is not covered parking where they park the cars. The breakfast place was a joke on service, took an hour for an order and blamed a single cook in the back but thats poor management and should keep to yourself. The hotel itself was clean and had a great atmosphere. The art was great. Room AC worked well and the cleaning crew were efficient and tidy. Good distance from some major attractions although the time for walking distance to some are greatly underestimated, unless you are running to the Arch or Union Station.
Stayed 2 nights in Oct 2025

10/10 Excellent

michael

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Unique hotel and very convenient to City Museum.
Stayed 2 nights in Oct 2025

10/10 Excellent

Mianfeng

Liked: Cleanliness
Stayed 1 night in Aug 2025

6/10 Okay

Pamela, Leawood

Traveled with partner
Hotel could be deserving 4 star iF.. entry was vacuumed during our multiple day stay more than 1 coffee cup and only2 towels in bathroom , replaced burnt out lightbulbs in room, fresh pastries ( they were a day old according to staff) , etc. Just not managed well.
Stayed 2 nights in Oct 2025

10/10 Excellent

KEVIN

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Oct 2025

10/10 Excellent

Lora

Stayed 1 night in Oct 2025

10/10 Excellent

Lyndsey

Stayed 1 night in Oct 2025