Compare Business Hotels in Durham
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Featured Durham Business Hotels

Royal Inn
3460 Hillsborough Rd Durham NC
$80 nightly
The price is $91 total per night
$91 total
Dec 16 - Dec 17
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Durham, Royal Inn is in the business district, a 4-minute drive from Duke University Hospital and 6 minutes from Cameron Indoor Stadium.

Wingate by Wyndham Raleigh Durham Airport RTP
5223 Page Rd Durham NC
$76 nightly
The price is $86 total per night
$86 total
Dec 23 - Dec 24
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Wingate by Wyndham Raleigh Durham Airport RTP in Durham, you'll be near the airport, within a 15-minute drive of Duke University and North Carolina State Fairgrounds.

Fairfield by Marriott Inn & Suites Durham
5219 Page Rd Durham NC
$116 nightly
The price is $132 total per night
$132 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Fairfield by Marriott Inn & Suites Durham in Durham, you'll be near the airport, within a 15-minute drive of Duke University and North Carolina State Fairgrounds.
Breakfast included
Free WiFi

DoubleTree Suites by Hilton Raleigh - Durham
2515 Meridian Pkwy Durham NC
$89 nightly
The price is $101 total per night
$101 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at DoubleTree Suites by Hilton Raleigh - Durham in Durham, you'll be in the business district, within a 15-minute drive of Duke University and University of North Carolina.
Pool
Free airport shuttle

La Quinta Inn & Suites by Wyndham Raleigh/Durham Southpoint
1910 Westpark Dr Durham NC
$68 nightly
The price is $78 total per night
$78 total
Dec 28 - Dec 29
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at La Quinta Inn & Suites by Wyndham Raleigh/Durham Southpoint in Durham, you'll be near the airport, within a 15-minute drive of Duke University and University of North Carolina.

Delta Hotels by Marriott Raleigh-Durham at Research Triangle Park
151 Tatum Drive Durham NC
$119 nightly
The price is $135 total per night
$135 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Delta Hotels by Marriott Raleigh-Durham at Research Triangle Park in Durham, you'll be in the business district, within a 15-minute drive of Duke University and North Carolina State Fairgrounds.

Hampton Inn & Suites Durham/North I-85
1542 North Gregson Street Durham NC
$103 nightly
The price is $117 total per night
$117 total
Dec 28 - Dec 29
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Hampton Inn & Suites Durham/North I-85 in Durham, you'll be in the business district, a 3-minute drive from Duke University and 6 minutes from Duke University Hospital.
Pool
Breakfast included

The Durham Hotel
315 East Chapel Hill Street Durham NC
$186 nightly
The price is $211 total per night
$211 total
Dec 17 - Dec 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at The Durham Hotel, you'll be centrally located in Durham, steps from Carolina Theatre and within a 10-minute walk of Durham Performing Arts Center.

Sleep Inn Raleigh Durham Airport
5208 Page Rd Durham NC
$70 nightly
The price is $79 total per night
$79 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
Free Cancellation
Located in Durham, Sleep Inn Raleigh Durham Airport is in the suburbs, within a 5-minute drive of Research Triangle Park and Lenovo.

Hilton Garden Inn Durham/University Medical Center
2102 West Main Street Durham NC
$96 nightly
The price is $109 total per night
$109 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Hilton Garden Inn Durham/University Medical Center in Durham (9th Street District), you'll be within a 5-minute drive of Duke University and Duke University Hospital.

Durham Marriott City Center
201 Foster St Durham NC
$134 nightly
The price is $152 total per night
$152 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Durham Marriott City Center places you in the heart of Durham, within a 5-minute drive of Duke University and North Carolina Central University.

Sheraton Imperial Hotel Raleigh-Durham Airport/RTP
4700 Emperor Blvd Durham NC
$105 nightly
The price is $119 total per night
$119 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Sheraton Imperial Hotel Raleigh-Durham Airport/RTP in Durham, you'll be in the business district, within a 15-minute drive of Duke University and North Carolina State Fairgrounds.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Durham hotels essential information
Accommodation | 788 hotels |
|---|---|
Lowest Price | $78 |
Highest Price | $211 |
Popular hotels | Royal Inn, Wingate by Wyndham Raleigh Durham Airport RTP, Fairfield by Marriott Inn & Suites Durham, DoubleTree Suites by Hilton Raleigh - Durham, La Quinta Inn & Suites by Wyndham Raleigh/Durham Southpoint, Delta Hotels by Marriott Raleigh-Durham at Research Triangle Park, Hampton Inn & Suites Durham/North I-85, The Durham Hotel, Sleep Inn Raleigh Durham Airport, Hilton Garden Inn Durham/University Medical Center, Durham Marriott City Center, Sheraton Imperial Hotel Raleigh-Durham Airport/RTP |
Most Recent Durham Hotel Reviews

Hilton Garden Inn Raleigh-Durham/Research Triangle Park
5 out of 5
Posted 17 hours ago
CheapTickets Verified Review
"Breakfast was delicious and fresh"
A verified traveler stayed at Hilton Garden Inn Raleigh-Durham/Research Triangle Park
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