Cheap Vacations in Panama

Choose two or more items and save on your trip:

Panama vacations

Price found within the past 48 hours. Click for updated prices.
Centriqo by Wynwood house

Centriqo by Wynwood house

3 out of 5
Price was $656, price is now $521 per person
$521
per person
Jul 24 - Jul 28
found 17 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Hotel Riu Playa Blanca - All Inclusive

Hotel Riu Playa Blanca - All Inclusive

3.5 out of 5
Price was $1,456, price is now $1,027 per person
$1,027
per person
Jul 23 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Charleston (CHS) to Rio Hato (RIH)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was $1,571, price is now $1,116 per person
$1,116
per person
Jul 23 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Charleston (CHS) to Panama City (PTY)
Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

4 out of 5
Price was $1,925, price is now $1,410 per person
$1,410
per person
Jul 30 - Aug 2
found 21 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Amarla Boutique Hotel Casco Viejo Adults Only

Amarla Boutique Hotel Casco Viejo Adults Only

3 out of 5
Casco Viejo
Price was $2,537, price is now $1,934 per person
$1,934
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
Price was $1,212, price is now $928 per person
$928
per person
Jul 30 - Aug 2
found 21 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Yoo by Wynwood House

Yoo by Wynwood House

4 out of 5
Calidonia
Price was $751, price is now $583 per person
$583
per person
Jul 24 - Jul 28
found 17 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Las Clementinas

Las Clementinas

3.5 out of 5
Casco Viejo
Price was $1,213, price is now $998 per person
$998
per person
Jul 23 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Charleston (CHS) to Panama City (PTY)
NAYARA Bocas del Toro

NAYARA Bocas del Toro

4 out of 5
Price was $2,572, price is now $2,118 per person
$2,118
per person
Jul 30 - Aug 2
found 21 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Salomon Urban Hub by Wynwood

Salomon Urban Hub by Wynwood

3.5 out of 5
Bella Vista
Price was $1,207, price is now $997 per person
$997
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
New York (NYC) to Panama City (PTY)

3-night Panama vacations

Price found within the past 48 hours. Click for updated prices.
San Francisco by Wynwood House

San Francisco by Wynwood House

3 out of 5
Price was $995, price is now $834 per person
$834
per person
Jul 17 - Jul 20
found 1 day ago
Roundtrip flight included
New York (NYC) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Price was $1,494, price is now $1,052 per person
$1,052
per person
Jul 23 - Jul 26
found 18 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

4 out of 5
Price was $1,925, price is now $1,410 per person
$1,410
per person
Jul 30 - Aug 2
found 21 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $1,276, price is now $945 per person
$945
per person
Jul 15 - Jul 18
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Price was $1,212, price is now $928 per person
$928
per person
Jul 30 - Aug 2
found 21 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,164, price is now $910 per person
$910
per person
Jul 15 - Jul 18
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,145, price is now $896 per person
$896
per person
Jul 15 - Jul 18
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Las Clementinas

Las Clementinas

3.5 out of 5
Price was $1,192, price is now $965 per person
$965
per person
Jul 15 - Jul 18
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $1,113, price is now $915 per person
$915
per person
Jul 15 - Jul 18
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
NAYARA Bocas del Toro

NAYARA Bocas del Toro

4 out of 5
Price was $2,572, price is now $2,118 per person
$2,118
per person
Jul 30 - Aug 2
found 21 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Price was $1,199, price is now $988 per person
$988
per person
Jul 15 - Jul 18
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

5 out of 5
Price was $1,337, price is now $1,121 per person
$1,121
per person
Jul 15 - Jul 18
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)

4-night Panama vacations

Price found within the past 48 hours. Click for updated prices.
Lesplanade by Wynwood House

Lesplanade by Wynwood House

3 out of 5
Price was $555, price is now $455 per person
$455
per person
Jul 24 - Jul 28
found 17 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Save 100% on your flight
Price was $2,019, price is now $1,189 per person
$1,189
per person
Jul 23 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Charleston (CHS) to Panama City (PTY)
Hotel Riu Playa Blanca - All Inclusive

Hotel Riu Playa Blanca - All Inclusive

3.5 out of 5
Price was $1,456, price is now $1,027 per person
$1,027
per person
Jul 23 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Charleston (CHS) to Rio Hato (RIH)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Price was $1,571, price is now $1,116 per person
$1,116
per person
Jul 23 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Charleston (CHS) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,188, price is now $896 per person
$896
per person
Jul 23 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Charleston (CHS) to Panama City (PTY)
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,129, price is now $862 per person
$862
per person
Jul 23 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Charleston (CHS) to Panama City (PTY)
Yoo by Wynwood House

Yoo by Wynwood House

4 out of 5
Price was $751, price is now $583 per person
$583
per person
Jul 24 - Jul 28
found 17 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $1,161, price is now $914 per person
$914
per person
Jul 30 - Aug 3
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Centriqo by Wynwood house

Centriqo by Wynwood house

3 out of 5
Price was $656, price is now $521 per person
$521
per person
Jul 24 - Jul 28
found 17 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
San Francisco by Wynwood House

San Francisco by Wynwood House

3 out of 5
Price was $1,093, price is now $875 per person
$875
per person
Jul 30 - Aug 3
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Casa La Costa By Wynwood House

Casa La Costa By Wynwood House

3.5 out of 5
Price was $621, price is now $501 per person
$501
per person
Jul 24 - Jul 28
found 17 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
The Sands by Wynwood House

The Sands by Wynwood House

3 out of 5
Price was $598, price is now $483 per person
$483
per person
Jul 24 - Jul 28
found 17 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)

5-night Panama vacations

Price found within the past 48 hours. Click for updated prices.
Salomon Urban Hub by Wynwood

Salomon Urban Hub by Wynwood

3.5 out of 5
Price was $662, price is now $512 per person
$512
per person
Jul 14 - Jul 19
found 11 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Save 100% on your flight
Price was $2,461, price is now $1,490 per person
$1,490
per person
Jul 13 - Jul 18
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Price was $1,585, price is now $1,051 per person
$1,051
per person
Jul 13 - Jul 18
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,353, price is now $957 per person
$957
per person
Jul 13 - Jul 18
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $1,384, price is now $989 per person
$989
per person
Jul 13 - Jul 18
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
The Gray by Wynwood House

The Gray by Wynwood House

3 out of 5
Price was $737, price is now $554 per person
$554
per person
Jul 14 - Jul 19
found 11 hours ago
Roundtrip flight included
San José (SJO) to Panama City (PTY)
Mini Design By Wynwood House

Mini Design By Wynwood House

3 out of 5
Price was $1,223, price is now $924 per person
$924
per person
Jul 20 - Jul 25
found 1 day ago
Roundtrip flight included
New York (NYC) to Panama City (PTY)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Price was $1,371, price is now $1,039 per person
$1,039
per person
Jul 13 - Jul 18
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Price was $1,335, price is now $1,012 per person
$1,012
per person
Jul 13 - Jul 18
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Hotel Casa Panamá

Hotel Casa Panamá

4 out of 5
Price was $1,182, price is now $902 per person
$902
per person
Jul 22 - Jul 27
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
La Cuadra by Wynwood House

La Cuadra by Wynwood House

3 out of 5
Price was $1,195, price is now $934 per person
$934
per person
Jul 24 - Jul 29
found 1 day ago
Roundtrip flight included
New York (NYC) to Panama City (PTY)
Hilton Panama

Hilton Panama

5 out of 5
Price was $1,557, price is now $1,229 per person
$1,229
per person
Jul 13 - Jul 18
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

6-7 night Panama vacations

Price found within the past 48 hours. Click for updated prices.
Hotel y Casino Central Park Panama

Hotel y Casino Central Park Panama

3 out of 5
Price was $1,087, price is now $900 per person
$900
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
New York (NYC) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Save 100% on your flight
Price was $2,592, price is now $1,691 per person
$1,691
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Hotel Casa Panamá

Hotel Casa Panamá

4 out of 5
Price was $1,284, price is now $965 per person
$965
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Amarla Boutique Hotel Casco Viejo Adults Only

Amarla Boutique Hotel Casco Viejo Adults Only

3 out of 5
Price was $2,537, price is now $1,934 per person
$1,934
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

5 out of 5
Price was $2,409, price is now $1,977 per person
$1,977
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
La Résidence Panamá

La Résidence Panamá

2.5 out of 5
Price was $1,344, price is now $1,109 per person
$1,109
per person
Jul 19 - Jul 26
found 19 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Salomon Urban Hub by Wynwood

Salomon Urban Hub by Wynwood

3.5 out of 5
Price was $1,207, price is now $997 per person
$997
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
New York (NYC) to Panama City (PTY)
Lesplanade by Wynwood House

Lesplanade by Wynwood House

3 out of 5
Price was $1,187, price is now $982 per person
$982
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
New York (NYC) to Panama City (PTY)
Casa Love by Wynwood House

Casa Love by Wynwood House

3 out of 5
Price was $1,194, price is now $997 per person
$997
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
New York (NYC) to Panama City (PTY)
Donovan Night Scene by Wynwood

Donovan Night Scene by Wynwood

3 out of 5
Price was $1,136, price is now $950 per person
$950
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
New York (NYC) to Panama City (PTY)
La Moderna Downtown Nights by Wynwood

La Moderna Downtown Nights by Wynwood

3 out of 5
Price was $1,124, price is now $943 per person
$943
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
New York (NYC) to Panama City (PTY)
La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood

3 out of 5
Price was $1,068, price is now $906 per person
$906
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
New York (NYC) to Panama City (PTY)

Top places to visit in Panama

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FlightsFlightsHotelsHotels

Panama City

Panama City

Flight deals to Panama

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Sun, Jul 5 - Thu, Jul 9
SJO
San José
PTY
Panama City
$264 Roundtrip, found 1 hour ago
$264
Roundtrip
found 1 hour ago
Select Copa flight, departing Sun, Jul 5 from San José to Panama City, returning Thu, Jul 9, priced at $264 found 1 hour ago
Sat, Jul 4 - Sat, Jul 11
MIA
Miami
PTY
Panama City
$312 Roundtrip, found 1 day ago
$312
Roundtrip
found 1 day ago
Select avianca flight, departing Sat, Jul 4 from Miami to Panama City, returning Sat, Jul 11, priced at $312 found 1 day ago
Wed, Jun 24 - Sun, Jun 28
SJO
San José
DAV
David
$341 Roundtrip, found 2 days ago
$341
Roundtrip
found 2 days ago
Select Copa flight, departing Wed, Jun 24 from San José to David, returning Sun, Jun 28, priced at $341 found 2 days ago

Top rated hotels for your Panama vacation

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Free Cancellation
Reserve now, pay when you stay
91.33 mi from city center
$124 nightly
The price is $137 total per night
$137 total
Jun 29 - Jun 30
Total with taxes and fees
Centrally located in Panama City, Hotel Riu Plaza Panama is within a 15-minute walk of Crown Casino and Fiesta Casino.
Pool
Breakfast included
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Free Cancellation
101.96 mi from city center
$142 nightly
The price is $156 total per night
$156 total
Jun 28 - Jun 29
Total with taxes and fees
Located in Tocumen, Crowne Plaza Panama Airport by IHG is within a 10-minute drive of Los Pueblos Commercial Center and Metromall Panama.
Pool
Free airport shuttle
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
92.79 mi from city center
$134 nightly
The price is $148 total per night
$148 total
Jul 4 - Jul 5
Total with taxes and fees
With a stay at Sheraton Grand Panama in Panama City (San Francisco), you'll be within a 5-minute drive of Multiplaza Pacific Mall and Cinta Costera.
Pool
Spa
Don't see what you're looking for?
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all package bookings with Flight + Hotel made on CheapTickets.com from 2019-04-01 - 2020-03-31 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.