Compare Business Hotels in Winston-Salem
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Featured Winston-Salem Business Hotels

Hawthorne Inn and Conference Center
420 High St Winston-Salem NC
$71 nightly
The price is $80 total per night
$80 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Hawthorne Inn and Conference Center in Winston-Salem, you'll be in the historical district, within a 10-minute drive of Wake Forest University and Benton Convention Center.
Pool
Pet friendly

Best Western Plus Hanes Mall Hotel
3330 Silas Creek Pkwy Winston-Salem NC
$79 nightly
The price is $89 total per night
$89 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Best Western Plus Hanes Mall Hotel in Winston-Salem, you'll be within a 10-minute drive of Wake Forest University and Hanes Mall.
Pool
Breakfast included

Fairfield Inn & Suites by Marriott Winston-Salem Downtown
125 S Main St Winston-Salem NC
$93 nightly
The price is $105 total per night
$105 total
Dec 26 - Dec 27
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Fairfield Inn & Suites by Marriott Winston-Salem Downtown in Winston-Salem, you'll be within a 10-minute drive of Wake Forest University and Frank L. Horton Museum Center.
Breakfast included
Free WiFi

Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall
1680 Westbrook Plaza Dr Winston-Salem NC
$105 nightly
The price is $119 total per night
$119 total
Dec 18 - Dec 19
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall in Winston-Salem, you'll be in the business district, within a 15-minute drive of Wake Forest University and Hanes Mall.
Pool
Breakfast included

Holiday Inn Exp Winston Salem by IHG
2520 Peters Creek Pkwy Winston-Salem NC
$75 nightly
The price is $85 total per night
$85 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
With a stay at Holiday Inn Exp Winston Salem by IHG in Winston-Salem, you'll be within a 15-minute drive of Wake Forest University and University of North Carolina School of the Arts.
Pool
Breakfast included

Best Western Plus University Inn
3050 University Pkwy Winston-Salem NC
$76 nightly
The price is $86 total per night
$86 total
Dec 15 - Dec 16
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Best Western Plus University Inn places you in the heart of Winston-Salem, within a 10-minute walk of Wake Forest University and Lawrence Joel Veterans Memorial Coliseum.
Pool
Breakfast included

La Quinta Inn & Suites by Wyndham Winston-Salem
2020 Griffith Rd Winston-Salem NC
$74 nightly
The price is $83 total per night
$83 total
Dec 15 - Dec 16
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at La Quinta Inn & Suites by Wyndham Winston-Salem in Winston-Salem, you'll be in a shopping district, within a 15-minute drive of Wake Forest University and Wilkes Regional.
Pool
Breakfast included

The Historic Brookstown Inn, Trademark Collection by Wyndham
200 Brookstown Ave Winston-Salem NC
$113 nightly
The price is $127 total per night
$127 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Winston-Salem, The Historic Brookstown Inn, Trademark Collection by Wyndham is in the historical district, within a 15-minute walk of Old Salem and Benton Convention Center.
Breakfast included
Parking included

Red Roof Inn Winston-Salem
100 Capitol Lodging Court Winston-Salem NC
$69 nightly
The price is $78 total per night
$78 total
Dec 13 - Dec 14
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Winston-Salem, Red Roof Inn Winston-Salem is a 2-minute drive from Hanes Mall and 6 minutes from Wake Forest University Baptist Medical Center.
Parking included
Free WiFi

DoubleTree by Hilton Winston Salem - University
5790 University Pkwy Winston-Salem NC
$73 nightly
The price is $82 total per night
$82 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at DoubleTree by Hilton Winston Salem - University in Winston-Salem, you'll be within a 5-minute drive of Wake Forest University and Grand 18-Winston-Salem.
Pool
Parking included

Kimpton Cardinal Hotel by IHG
51 East 4th St Winston-Salem NC
$156 nightly
The price is $176 total per night
$176 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Free Cancellation
In the heart of Winston-Salem, Kimpton Cardinal Hotel by IHG is within a 5-minute drive of Benton Convention Center and Old Salem.
Pet friendly
Restaurant

Embassy Suites Hotel Winston-Salem
460 N Cherry St Winston-Salem NC
$95 nightly
The price is $108 total per night
$108 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Embassy Suites Hotel Winston-Salem in Winston-Salem, you'll be within a 10-minute drive of Wake Forest University and Benton Convention Center.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Winston-Salem hotels essential information
Accommodation | 411 hotels |
|---|---|
Lowest Price | $78 |
Highest Price | $176 |
Popular hotels | Hawthorne Inn and Conference Center, Best Western Plus Hanes Mall Hotel, Fairfield Inn & Suites by Marriott Winston-Salem Downtown, Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall, Holiday Inn Exp Winston Salem by IHG, Best Western Plus University Inn, La Quinta Inn & Suites by Wyndham Winston-Salem, The Historic Brookstown Inn, Trademark Collection by Wyndham, Red Roof Inn Winston-Salem, DoubleTree by Hilton Winston Salem - University, Kimpton Cardinal Hotel by IHG, Embassy Suites Hotel Winston-Salem |
Most Recent Winston-Salem Hotel Reviews

Comfort Suites Hanes Mall
5 out of 5
Posted 1 day ago
CheapTickets Verified Review
"Room was clean and very comfortable. Front desk staff was very nice."
A verified traveler stayed at Comfort Suites Hanes Mall
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