St. Charles Guest Houses

Get more for your budget and save up to 50% off select Secret Bargain hotels

Get even more value with CheapTickets Price Guarantee!

Change your flight without a fee on select flights

Guest Houses in St. Charles

The Inn at Elijah McLeans

602 W Front St Washington MO

$132 nightly

$151 total

Sep 21 - Sep 22

Total with taxes and fees

Free Cancellation

Reserve now, pay when you stay

With a stay at The Inn at Elijah McLeans in Washington, you'll be in the historical district, just a 3-minute walk from Rotary Park and 8 minutes by foot from Railroad Heritage Park.

Parking included

Free WiFi

Cozy, Fun, and One-Of-A-Kind!

St. Louis MO

$121 nightly

$131 total

Aug 30 - Aug 31

Total with taxes and fees

With a stay at this guesthouse in St. Louis (Shaw), you'll be within a 5-minute drive of St. Louis University and Forest Park.

Air conditioning

Parking available

Grand Center Inn

3716 Grandel Square St. Louis MO

$179 nightly

$211 total

Aug 27 - Aug 28

Total with taxes and fees

Located in St. Louis (Grand Center), Grand Center Inn is within a 5-minute walk of Powell Symphony Hall and Fox Theater.

Parking included

Free WiFi

The Loft on Main | Steps to Dining & Nightlife

Saint Charles MO

With a stay at this guesthouse in St. Charles (St. Charles Historic District), you'll be a 1-minute drive from Ameristar Casino St. Charles and 6 minutes from Hollywood Casino Amphitheatre.

Pet friendly

Air conditioning

Charming Home with Country Views

Grafton IL

$372 nightly

$394 total

Aug 26 - Aug 27

Total with taxes and fees

With a stay at this guesthouse in Grafton, you'll be within a 10-minute drive of Mississippi River and Grafton SkyTour.

Free WiFi

Air conditioning

Spacious home in Historic St. Charles, Near Main Street + self-serve breakfast

St Charles MO

With a stay at this guesthouse, you'll be centrally located in St. Charles, a 4-minute drive from Ameristar Casino St. Charles and 7 minutes from Hollywood Casino Amphitheatre.

Breakfast included

Free WiFi

In the center of all Historic Main Street has to offer

Grafton IL

$582 nightly

$626 total

Aug 26 - Aug 27

Total with taxes and fees

A stay at this guesthouse places you in the heart of Grafton, within a 15-minute walk of Mississippi River and Grafton Winery & Brewhaus.

Pet friendly

Air conditioning

Lou Luxe- Speakeasy, EPIC Arcade, Hottub & FirePit

3137 Nebraska Ave St. Louis MO

With a stay at Lou Luxe- Speakeasy, EPIC Arcade, Hottub & FirePit, you'll be centrally located in St. Louis, a 4-minute drive from St. Louis University and 6 minutes from St. Louis Union Station.

Hot Tub

Pet friendly

Rustic Retreats

211 W. Main Grafton IL

With a stay at Rustic Retreats in Grafton, you'll be within a 15-minute walk of Mississippi River and Grafton Winery & Brewhaus.

Parking included

Free WiFi

Clean Beautiful Multi Level Loft

1000 Washington Ave St. Louis MO

With a stay at Clean Beautiful Multi Level Loft in St. Louis (Downtown St. Louis), you'll be a 3-minute walk from America's Center Convention Complex and 13 minutes by foot from Busch Stadium.

Free WiFi

Restaurant

Don't see what you're looking for?

See all available properties in St. Charles

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.