Compare Cheap Hotels in Southern Minnesota

Secret Bargains - Save an extra 10% or more on select hotels

Start date: Check-in selected.
To Date
End date: Check-out

Get more for your budget and save up to 50% off select Secret Bargain hotels

Get even more value with CheapTickets Price Guarantee!

Change your flight without a fee on select flights

Cheap Southern Minnesota Hotels

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
$149 nightly
The price is $172 total per night
$172 total
Dec 6 - Dec 7
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
76.87 mi from city center
A stay at Kahler Grand Hotel places you in the heart of Rochester, within a 5-minute walk of Mayo Clinic and University of Minnesota-Rochester.
Pool
Hot Tub
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
$155 nightly
The price is $178 total per night
$178 total
Dec 6 - Dec 7
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
76.77 mi from city center
Kahler Inn and Suites - Mayo Clinic Area is centrally located in Rochester, a 3-minute walk from Mayo Clinic and 7 minutes by foot from University of Minnesota-Rochester.
Pool
Breakfast included
Hampton Inn Rochester-South

Hampton Inn Rochester-South

2.5 out of 5
1755 S Broadway Rochester MN
$82 nightly
The price is $95 total per night
$95 total
Dec 26 - Dec 27
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
77.05 mi from city center
With a stay at Hampton Inn Rochester-South in Rochester, you'll be within a 5-minute drive of Mayo Clinic and Mayo Clinic Hospital - Saint Marys Campus.
Pool
Hot Tub
Spark by Hilton Rochester South

Spark by Hilton Rochester South

3 out of 5
4165 Maine Ave SE Rochester MN
$69 nightly
The price is $79 total per night
$79 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
77.67 mi from city center
Located in Rochester, Spark by Hilton Rochester South is within a 10-minute drive of Apache Mall and Olmsted County Fairgrounds.
Pool
Breakfast included
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
$129 nightly
The price is $149 total per night
$149 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
76.89 mi from city center
With a stay at Hyatt House Rochester/Mayo Clinic Area, you'll be centrally located in Rochester, within a 10-minute walk of University of Minnesota-Rochester and Mayo Civic Center.
Pool
Hot Tub
The Berkman

The Berkman

3 out of 5
217 14th Ave SW Rochester MN
$177 nightly
The price is $203 total per night
$203 total
Dec 6 - Dec 7
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
75.95 mi from city center
Located in Rochester (Folwell), The Berkman is steps from Mayo Clinic Hospital - Saint Marys Campus and a 2-minute drive from Mayo Clinic.
Pool
Kitchen
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
$80 nightly
The price is $92 total per night
$92 total
Dec 6 - Dec 7
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
75.91 mi from city center
With a stay at Med City Inn & Suites - Mayo Clinic Area, you'll be centrally located in Rochester, within a 5-minute drive of Mayo Clinic and Mayo Clinic Hospital - Saint Marys Campus.
Pool
Hot Tub
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
$67 nightly
The price is $77 total per night
$77 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Free Cancellation
77.03 mi from city center
With a stay at Hotel Indigo Rochester – Mayo Clinic Area by IHG, you'll be centrally located in Rochester, steps from University of Minnesota-Rochester and within a 10-minute walk of Mayo Park.
Pet friendly
Free WiFi
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
$73 nightly
The price is $84 total per night
$84 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
77.02 mi from city center
When you stay at AmericInn by Wyndham Rochester Near Mayo Clinic in Rochester, you'll be in a shopping district, within a 5-minute drive of Olmsted County Fairgrounds and Apache Mall.
Pool
Hot Tub
Aspen Suites

Aspen Suites

3 out of 5
1211 2nd Street Rochester MN
$137 nightly
The price is $158 total per night
$158 total
Dec 12 - Dec 13
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
76.07 mi from city center
With a stay at Aspen Suites, you'll be centrally located in Rochester, steps from Mayo Clinic Hospital - Saint Marys Campus and within a 5-minute drive of Mayo Clinic.
Pool
Hot Tub
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
$89 nightly
The price is $102 total per night
$102 total
Dec 26 - Dec 27
Total with taxes and fees
Free Cancellation
76.21 mi from city center
With a stay at EVEN Hotel Rochester - Mayo Clinic Area by IHG in Rochester (Kutzky Park), you'll be steps from Mayo Clinic Hospital - Saint Marys Campus and 12 minutes by foot from Mayo Clinic.
Pool
Hot Tub
Brentwood Inn & Suites

Brentwood Inn & Suites

2.5 out of 5
123 Fourth Ave. NW Rochester MN
$125 nightly
The price is $144 total per night
$144 total
Dec 6 - Dec 7
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
76.75 mi from city center
Brentwood Inn & Suites is centrally located in Rochester, a 4-minute walk from Mayo Clinic and 8 minutes by foot from University of Minnesota-Rochester.
Breakfast included
Free WiFi
Don't see what you're looking for?
See all available properties in Southern Minnesota
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Often, one of the most difficult things about booking a hotel is finding the best time to go. The cost of staying in hotels in could vary significantly, depending on the time of the year chosen. If you would like to figure out the most suitable time to take a trip then using CheapTickets could be the best option for you. We will be able to provide information on hotels in to ensure that you get the best deal possible. So if you are looking for a booking website that will streamline the process and offer good prices, then log in and get booking.

Southern Minnesota hotels essential information

Accommodation
1,187 hotels
Lowest Price
$77
Highest Price
$203
Popular hotels
Kahler Grand Hotel, Kahler Inn and Suites - Mayo Clinic Area, Hampton Inn Rochester-South, Spark by Hilton Rochester South, Hyatt House Rochester/Mayo Clinic Area, The Berkman, Med City Inn & Suites - Mayo Clinic Area, Hotel Indigo Rochester – Mayo Clinic Area by IHG, AmericInn by Wyndham Rochester Near Mayo Clinic, Aspen Suites, EVEN Hotel Rochester - Mayo Clinic Area by IHG, Brentwood Inn & Suites

Most Recent Southern Minnesota Hotel Reviews

Hampton Inn Rochester-South

Hampton Inn Rochester-South

5 out of 5
Posted 1 day ago
CheapTickets Verified Review
"Poor Wi-Fi signal so TV does not work properly."
A verified traveler from Grand Forks stayed at Hampton Inn Rochester-South
Hampton Inn Rochester-South