Compare Luxury Hotels in Panama City
Secret Bargains - Save an extra 10% or more on select Luxury Hotels
Get more for your budget and save up to 50% off select Secret Bargain hotels
Get even more value with CheapTickets Price Guarantee!
Change your flight without a fee on select flights
Featured Panama City Luxury Hotels

JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
$255 nightly
The price is $281 total per night
$281 total
May 30 - May 31
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Centrally located in Panama City, JW Marriott Panama is within a 15-minute walk of Multiplaza Pacific Mall and Avenida Balboa.
Pool
Spa

Bristol Panama, a Registry Collection Hotel
Avenida Aquilino de La Guardia Panama City Panama
$183 nightly
The price is $201 total per night
$201 total
May 7 - May 8
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Bristol Panama, a Registry Collection Hotel, you'll be centrally located in Panama City, steps from Calle 50 and within a 10-minute walk of Soho City Center.
Pool
Spa

Waldorf Astoria Panama
47th St. & Uruguay Street Panama City Panama
$271 nightly
The price is $298 total per night
$298 total
May 31 - Jun 1
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Waldorf Astoria Panama places you in the heart of Panama City, within a 5-minute drive of Multicentro Panama and Multiplaza Pacific Mall.
Pool
Spa

American Trade Hotel
Plaza Herrera Casco Viejo Panama City Panama
$221 nightly
The price is $243 total per night
$243 total
Jun 1 - Jun 2
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
American Trade Hotel is in the heart of Panama City, within a 5-minute walk of Museum of History Panama and Independence Square.

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
56 y 57 East Street, Obarrio Panama City Panama
$159 nightly
The price is $175 total per night
$175 total
May 9 - May 10
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Sortis Hotel, Spa & Casino, Autograph Collection by Marriott places you in the heart of Panama City, a short 5-minute walk from Via Espana and within 2 minutes by car from Avenida Balboa.

Hilton Panama
Balboa Ave. and Aquilino De La Guardia Panama City
$237 nightly
The price is $261 total per night
$261 total
May 31 - Jun 1
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Hilton Panama, you'll be centrally located in Panama City, steps from Cinta Costera and within a 10-minute walk of Multicentro Panama.
Pool
Spa

Megapolis Hotel Panamá
Ave. Balboa al lado de Multicentro, 63 Panama City Panamá Province
With a stay at Megapolis Hotel Panamá, you'll be centrally located in Panama City, steps from Multicentro Panama and Avenida Balboa.

Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
$147 nightly
The price is $162 total per night
$162 total
May 2 - May 3
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Las Americas Golden Tower Panama, you'll be centrally located in Panama City, a 4-minute walk from Multicentro Panama and a 2-minute drive from Fiesta Casino.
Pool
Spa

Marriott Panama Hotel
Roosevelt Ave., Allbrook Mall Panama City Panama
$161 nightly
The price is $177 total per night
$177 total
May 9 - May 10
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Marriott Panama Hotel places you in the heart of Panama City, steps from Albrook Shopping Mall and a 3-minute drive from Anthropological Museum Reina Torres de Arauz.

Doubletree By Hilton Panama City El Carmen
Via Espana Ave. Federico Boyd Bel Panama City Panama Province
With a stay at Doubletree By Hilton Panama City El Carmen, you'll be centrally located in Panama City, a short 8-minute walk from Avenida Balboa and 11 minutes by foot from Cinta Costera.

Metro Hotel Panama
Via Veneto, Calle D El Cangrejo Panama City Panama
$45 nightly
The price is $50 total per night
$50 total
May 31 - Jun 1
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Metro Hotel Panama, you'll be centrally located in Panama City, within a 5-minute drive of Via Espana and Avenida Balboa.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Panama City hotels essential information
Accommodation | 1,522 hotels |
|---|---|
Lowest Price | $50 |
Highest Price | $298 |
Popular hotels | JW Marriott Panama, Bristol Panama, a Registry Collection Hotel, Waldorf Astoria Panama, American Trade Hotel, Sortis Hotel, Spa & Casino, Autograph Collection by Marriott, Hilton Panama, Megapolis Hotel Panamá, Las Americas Golden Tower Panama, Marriott Panama Hotel, Doubletree By Hilton Panama City El Carmen, Metro Hotel Panama, Eurostars Panama City |
Most Recent Panama City Hotel Reviews

Waymore Hotel Spa & Casino
4 out of 5
Posted 1 hour ago
CheapTickets Verified Review
"The rooms were nice and clean . The breakfast was excellent. The location of hotel is located near shops which was perfect for my friends."
A verified traveler stayed at Waymore Hotel Spa & Casino
More to Explore in Panama City
Top Picks
- Oceanfront Hotels in Panama City
- Hotels with Air Conditioning in Casco Viejo
- Cheap Hotels in Casco Viejo
- Extended Stay Hotels in Panama City
- Hotels with Airport Transfers in Casco Viejo
- Pet Friendly Hotels in Casco Viejo
- Kid Friendly Hotels in Panama City
- 5 Star Hotels in Panama City
- Romantic Getaways & Hotels in Casco Viejo
- Golf Resorts & in Panama City
- Casino Resorts & in Casco Viejo
- Hotels with Balconies in Casco Viejo
- Hotels with Bars in Casco Viejo
- Business Hotels in Panama City
- Hotels with Free Breakfast in Panama City
- Adventure Sport Hotels in Casco Viejo
- Oceanfront Hotels in Casco Viejo
- Hotels with Balconies in Panama City
- Panama City Hotels
- Hotels with Free Breakfast in Casco Viejo
- Business Hotels in Casco Viejo
- Hotels with a Wedding Venue in Panama City
- 3 Star Hotels in Panama City
- Wyndham Hotels in Panama City
- Hotels with an Indoor Pool in Panama City
- Flights from Madrid to Panama City
- Flights from Burlington to Panama City
- Flights from Hamilton to Panama City
- Flights from Daytona Beach to Panama City
- Flights from Lima to Panama City
- Flights from Lapu-Lapu to Panama City
- Flights from Berlin to Panama City
- Flights from San Salvador to Panama City
- Flights from Santa Fe to Panama City
- Flights from Baton Rouge to Panama City
- Flights from Seattle to Panama City
- Flights from Cordoba to Panama City
- Flights from Tel Aviv to Panama City
- Flights from Midland to Panama City
- Flights from Dayton to Panama City
- Flights from Vista to Panama City
- Flights from Corpus Christi to Panama City
- Flights from Belize City to Panama City
- Flights from Marrakech to Panama City
- Flights from Bozeman to Panama City
- Flights from New York to Panama City
- Flights from Atlanta to Panama City
- Flights from La Paz to Panama City
- Flights from Grand Rapids to Panama City
- Flights from San Antonio to Panama City
- Flights from Memphis to Panama City
- Flights from Sydney to Panama City
- Flights from Springfield to Panama City
- Flights from Salt Lake City to Panama City
- Flights from Kansas City to Panama City
- Flights from Paris to Panama City
- Flights from Indianapolis to Panama City
- Flights from Reynosa to Panama City
- Flights from Winnipeg to Panama City
- Flights from Tulsa to Panama City
- Flights from Tucson to Panama City
- Flights from Boston to Panama City
- Flights from State College to Panama City
- Flights from Kelowna to Panama City
- Flights from Cali to Panama City
- Flights from San Pedro Sula to Panama City
- Flights from Sao Paulo to Panama City
- Flights from Dallas to Panama City
- Flights from Guatemala City to Panama City
- Flights from Mobile to Panama City
- Flights from Biloxi to Panama City
- Flights from Sarasota to Panama City
- Flights from Frankfurt to Panama City
- Flights from Mérida to Panama City
- Flights from Portland to Panama City
- Flights from Istanbul to Panama City
- Flights from Providence to Panama City
- Flights from Ixtapa - Zihuatanejo to Panama City
- Flights from Andros Town to Panama City
- Flights from North Pacific Coast to Panama City
- Flights from Chicago to Panama City
- Flights from Minneapolis - St. Paul to Panama City
- Flights from Little Rock to Panama City
- Flights from Fort Lauderdale to Panama City
- Flights from Durango to Panama City
- Flights from Warsaw to Panama City
- Flights from Alexandria to Panama City
- Flights from Louisville to Panama City
- Flights from Portland to Panama City
- Flights from Rio de Janeiro to Panama City
- Flights from Mombasa to Panama City
- Flights from Flint to Panama City
- Flights from Bend to Panama City
- Flights from Austin to Panama City
- Flights from San Francisco to Panama City
- Flights to Panama City
- Flights from Roanoke to Panama City
- Flights from Bogotá to Panama City
- Flights from Cleveland to Panama City
- Flights from Ho Chi Minh City to Panama City






