Compare Luxury Hotels in Panama City
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Featured Panama City Luxury Hotels
JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
$269 nightly
The price is $296 total per night
$296 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Centrally located in Panama City, JW Marriott Panama is within a 15-minute walk of Multiplaza Pacific Mall and Avenida Balboa.
Bristol Panama, a Registry Collection Hotel
Avenida Aquilino de La Guardia Panama City Panama
$200 nightly
The price is $220 total per night
$220 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Bristol Panama, a Registry Collection Hotel, you'll be centrally located in Panama City, steps from Calle 50 and within a 10-minute walk of Soho City Center.
Waldorf Astoria Panama
47th St. & Uruguay Street Panama City Panama
$180 nightly
The price is $198 total per night
$198 total
Dec 17 - Dec 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Waldorf Astoria Panama places you in the heart of Panama City, within a 5-minute drive of Multicentro Panama and Multiplaza Pacific Mall.
American Trade Hotel
Plaza Herrera Casco Viejo Panama City Panama
$262 nightly
The price is $289 total per night
$289 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
American Trade Hotel is in the heart of Panama City, within a 5-minute walk of Museum of History Panama and Independence Square.
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
56 y 57 East Street, Obarrio Panama City Panama
$159 nightly
The price is $175 total per night
$175 total
Dec 13 - Dec 14
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Sortis Hotel, Spa & Casino, Autograph Collection by Marriott places you in the heart of Panama City, within a 15-minute walk of Via Espana and Avenida Balboa.
Hilton Panama
Balboa Ave. and Aquilino De La Guardia Panama City
$186 nightly
The price is $205 total per night
$205 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Hilton Panama places you in the heart of Panama City, within a 5-minute drive of Multicentro Panama and Multiplaza Pacific Mall.
Megapolis Hotel Panamá
Ave. Balboa al lado de Multicentro, 63 Panama City Panamá Province
With a stay at Megapolis Hotel Panamá, you'll be centrally located in Panama City, steps from Multicentro Panama and Avenida Balboa.
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
$175 nightly
The price is $192 total per night
$192 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Las Americas Golden Tower Panama, you'll be centrally located in Panama City, a 4-minute walk from Multicentro Panama and a 2-minute drive from Fiesta Casino.
Marriott Panama Hotel
Roosevelt Ave., Allbrook Mall Panama City Panama
$142 nightly
The price is $156 total per night
$156 total
Dec 12 - Dec 13
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Marriott Panama Hotel places you in the heart of Panama City, steps from Albrook Shopping Mall and a 3-minute drive from Anthropological Museum Reina Torres de Arauz.
Doubletree By Hilton Panama City El Carmen
Via Espana Ave. Federico Boyd Bel Panama City Panama Province
With a stay at Doubletree By Hilton Panama City El Carmen, you'll be centrally located in Panama City, a 8-minute walk from Avenida Balboa and 11 minutes by foot from Cinta Costera.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Panama City hotels essential information
Accommodation | 1,633 hotels |
|---|---|
Lowest Price | $156 |
Highest Price | $296 |
Popular hotels | JW Marriott Panama, Bristol Panama, a Registry Collection Hotel, Waldorf Astoria Panama, American Trade Hotel, Sortis Hotel, Spa & Casino, Autograph Collection by Marriott, Hilton Panama, Megapolis Hotel Panamá, Las Americas Golden Tower Panama, Marriott Panama Hotel, Doubletree By Hilton Panama City El Carmen, Metro Hotel Panama, Eurostars Panama City |
Most Recent Panama City Hotel Reviews
Hotel Riu Plaza Panama
5 out of 5
Posted 12 hours ago
CheapTickets Verified Review
"The Staff was Amazing. Pamela at the hotels store mad my fiancé and I feel like family. The rooms are spacious and clean. "
A verified traveler stayed at Hotel Riu Plaza Panama
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