Compare Luxury Hotels in Panama
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Featured Panama Luxury Hotels
JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
$289 nightly
The price is $318 total per night
$318 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Centrally located in Panama City, JW Marriott Panama is within a 15-minute walk of Multiplaza Pacific Mall and Avenida Balboa.
Pool
Spa
Bristol Panama, a Registry Collection Hotel
Avenida Aquilino de La Guardia Panama City Panama
$220 nightly
The price is $242 total per night
$242 total
Dec 20 - Dec 21
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Bristol Panama, a Registry Collection Hotel, you'll be centrally located in Panama City, steps from Calle 50 and within a 10-minute walk of Soho City Center.
Pool
Spa
Waldorf Astoria Panama
47th St. & Uruguay Street Panama City Panama
$221 nightly
The price is $243 total per night
$243 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Waldorf Astoria Panama places you in the heart of Panama City, within a 5-minute drive of Multicentro Panama and Multiplaza Pacific Mall.
Pool
Spa
American Trade Hotel
Plaza Herrera Casco Viejo Panama City Panama
$262 nightly
The price is $289 total per night
$289 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
American Trade Hotel is in the heart of Panama City, within a 5-minute walk of Museum of History Panama and Independence Square.
Pool
Pet friendly
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
56 y 57 East Street, Obarrio Panama City Panama
$159 nightly
The price is $175 total per night
$175 total
Dec 20 - Dec 21
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Sortis Hotel, Spa & Casino, Autograph Collection by Marriott places you in the heart of Panama City, within a 15-minute walk of Via Espana and Avenida Balboa.
Pool
Spa
Hilton Panama
Balboa Ave. and Aquilino De La Guardia Panama City
$186 nightly
The price is $205 total per night
$205 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Hilton Panama places you in the heart of Panama City, within a 5-minute drive of Multicentro Panama and Multiplaza Pacific Mall.
Pool
Spa
Megapolis Hotel Panamá
Ave. Balboa al lado de Multicentro, 63 Panama City Panamá Province
With a stay at Megapolis Hotel Panamá, you'll be centrally located in Panama City, steps from Multicentro Panama and Avenida Balboa.
Hot Tub
All inclusive
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
340 Calle 3ra Buenaventura El Chiru Cocle
$199 nightly
The price is $219 total per night
$219 total
Dec 17 - Dec 18
Total with taxes and fees
With a stay at The Buenaventura Golf & Beach Resort Panama, Autograph Collection in El Chiru, you'll be 1.8 mi (2.9 km) from Buenaventura Marina and 8 mi (12.9 km) from Santa Clara Beach.
On private beach
Pool
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
$175 nightly
The price is $192 total per night
$192 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Las Americas Golden Tower Panama, you'll be centrally located in Panama City, a 4-minute walk from Multicentro Panama and a 2-minute drive from Fiesta Casino.
Pool
Spa
Marriott Panama Hotel
Roosevelt Ave., Allbrook Mall Panama City Panama
$142 nightly
The price is $156 total per night
$156 total
Dec 19 - Dec 20
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Marriott Panama Hotel places you in the heart of Panama City, steps from Albrook Shopping Mall and a 3-minute drive from Anthropological Museum Reina Torres de Arauz.
Pool
Pet friendly
Doubletree By Hilton Panama City El Carmen
Via Espana Ave. Federico Boyd Bel Panama City Panama Province
With a stay at Doubletree By Hilton Panama City El Carmen, you'll be centrally located in Panama City, a 8-minute walk from Avenida Balboa and 11 minutes by foot from Cinta Costera.
Pool
Parking included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Panama Luxury Hotels essential information
Luxury Hotels in Panama |
67 |
|---|---|
Highest price | $318 |
Cheapest price | $156 |
Total number of hotels in Panama | 3,581 |
Popular hotels | JW Marriott Panama, Bristol Panama, a Registry Collection Hotel, Waldorf Astoria Panama, American Trade Hotel, Sortis Hotel, Spa & Casino, Autograph Collection by Marriott, Hilton Panama, Megapolis Hotel Panamá, The Buenaventura Golf & Beach Resort Panama, Autograph Collection, Las Americas Golden Tower Panama, Marriott Panama Hotel, Doubletree By Hilton Panama City El Carmen, Metro Hotel Panama |
Most Recent Panama Hotel Reviews
Plaza Paitilla Inn Hotel
5 out of 5
Posted 2 days ago
CheapTickets Verified Review
"Everything! View breakfast friendliness"
A verified traveler stayed at Plaza Paitilla Inn Hotel
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