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Best Western in Opelousas

Evangeline Downs Hotel, an Ascend Collection Hotel
2235 Creswell Ln Ext, Lot B Opelousas LA
$101 nightly
The price is $119 total per night
$119 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
1.36 mi from city center
With a stay at Evangeline Downs Hotel, an Ascend Collection Hotel in Opelousas, you'll be 17.7 mi (28.4 km) from Pelican Park and 23.3 mi (37.6 km) from University of Louisiana at Lafayette.
Pool
Breakfast included

Days Inn & Suites by Wyndham Opelousas
5761 I-49 S Service Rd Opelousas LA
$65 nightly
The price is $75 total per night
$75 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.44 mi from city center
With a stay at Days Inn & Suites by Wyndham Opelousas in Opelousas, you'll be 1.7 mi (2.8 km) from Evangeline Downs Racetrack & Casino and 21.2 mi (34.2 km) from Moore Park.
Pool
Breakfast included

Holiday Inn Express & Suites Opelousas by IHG
5696 I-49 N Service Rd Opelousas LA
$89 nightly
The price is $105 total per night
$105 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
1.42 mi from city center
A stay at Holiday Inn Express & Suites Opelousas by IHG places you in the heart of Opelousas, within a 5-minute drive of South Louisiana Community College T. H. Harris Campus and South Park.
Pool
Breakfast included

Spark by Hilton Opelousas
5454 I-49 North Service Rd. Opelousas LA
$65 nightly
The price is $76 total per night
$76 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.59 mi from city center
A stay at Spark by Hilton Opelousas places you in the heart of Opelousas, within a 5-minute drive of South Louisiana Community College T. H. Harris Campus and South Park.
Pool
Breakfast included

Hampton Inn Opelousas
1700 Commerce Blvd Opelousas LA
$119 nightly
The price is $140 total per night
$140 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.14 mi from city center
Located in Opelousas, Hampton Inn Opelousas is within a 5-minute drive of South Louisiana Community College T. H. Harris Campus and South Park.
Pool
Breakfast included

Studio 6 Opelousas, LA
5791 I-49 S Service Road Opelousas LA
$65 nightly
The price is $77 total per night
$77 total
Dec 6 - Dec 7
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
1.43 mi from city center
With a stay at Studio 6 Opelousas, LA in Opelousas, you'll be within a 5-minute drive of South Louisiana Community College T. H. Harris Campus and South Park.
Pet friendly
Parking included

Motel 6 Opelousas, LA
4165 I-49 S Service Rd Opelousas LA
$60 nightly
The price is $71 total per night
$71 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
3.94 mi from city center
A stay at Motel 6 Opelousas, LA places you in the heart of Opelousas, within a 10-minute walk of Opelousas General Health System South Campus and St. Landry Extended Care Hospital.
Pet friendly
Parking included

DoubleTree by Hilton Hotel Lafayette
1521 W Pinhook Rd Lafayette LA
$84 nightly
The price is $97 total per night
$97 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
23.56 mi from city center
With a stay at DoubleTree by Hilton Hotel Lafayette in Lafayette, you'll be on a river, within a 5-minute drive of Cajundome and Acadian Village Shopping Center.
Pool
Free airport shuttle

Tru by Hilton Lafayette River Ranch
1310 Camellia Blvd Lafayette LA
$70 nightly
The price is $80 total per night
$80 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
25.37 mi from city center
With a stay at Tru by Hilton Lafayette River Ranch in Lafayette (River Ranch), you'll be within a 10-minute drive of Cajundome and Our Lady of Lourdes Heart Hospital.
Pool
Breakfast included

Sonesta ES Suites Lafayette Airport
807 Hugh Wallis Rd S Lafayette LA
$71 nightly
The price is $82 total per night
$82 total
Dec 11 - Dec 12
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
23.81 mi from city center
With a stay at Sonesta ES Suites Lafayette Airport in Lafayette, you'll be near the airport, within a 10-minute drive of Cajundome and Ostrich Park.
Breakfast included
Pet friendly

Comfort Suites Oil Center
114 Rue Fernand Lafayette LA
$67 nightly
The price is $77 total per night
$77 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
23.84 mi from city center
With a stay at Comfort Suites Oil Center, you'll be centrally located in Lafayette, within a 10-minute drive of Cajundome and Acadian Village Shopping Center.
Pool
Breakfast included

La Quinta Inn & Suites by Wyndham Lafayette Oil Center
1321 W Pinhook Rd Lafayette LA
$82 nightly
The price is $94 total per night
$94 total
Dec 7 - Dec 8
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
23.38 mi from city center
With a stay at La Quinta Inn & Suites by Wyndham Lafayette Oil Center in Lafayette, you'll be within a 5-minute drive of Cajundome and Frem Boustany Convention Center at The Heymann Center.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Opelousas hotels essential information
Accommodation | 421 hotels |
|---|---|
Lowest Price | $71 |
Highest Price | $140 |
Popular hotels | Evangeline Downs Hotel, an Ascend Collection Hotel, Days Inn & Suites by Wyndham Opelousas, Holiday Inn Express & Suites Opelousas by IHG, Spark by Hilton Opelousas, Hampton Inn Opelousas, Studio 6 Opelousas, LA, Motel 6 Opelousas, LA, DoubleTree by Hilton Hotel Lafayette, Tru by Hilton Lafayette River Ranch, Sonesta ES Suites Lafayette Airport, Comfort Suites Oil Center, La Quinta Inn & Suites by Wyndham Lafayette Oil Center |
Most Recent Opelousas Hotel Reviews

Hampton Inn Opelousas
5 out of 5
Posted 3 days ago
CheapTickets Verified Review
"The room was very comfortable very clean. The staff was so friendly and welcoming. Breakfast very good. Overall 10"
A verified traveler stayed at Hampton Inn Opelousas





