Compare Hotels with Air Conditioning in South Carolina

With a stay at The Francis Marion Hotel, you'll be centrally located in Charleston, steps from Marion Square and College of Charleston.

With a stay at Sea Mist Oceanfront Resort, you'll be centrally located in Myrtle Beach, steps from Myrtle Beach Beaches and 12 minutes by foot from Family Kingdom Amusement Park.

With a stay at Sheraton Columbia Downtown Hotel, you'll be centrally located in Columbia, steps from Columbia Museum of Art and within a 5-minute walk of South Carolina State House.

Located in Yemassee, Red Roof Inn Yemassee is in a rural location, within a 15-minute drive of Carolina Cider Company and Auldbrass.

With a stay at Days Inn by Wyndham Charleston Historic District, you'll be centrally located in Charleston, steps from Charleston City Market and 8 minutes by foot from College of Charleston.

With a stay at Howard Johnson by Wyndham Beaufort/Parris Island in Beaufort, you'll be near the airport, within a 10-minute drive of Marine Corps Recruit Depot Parris Island and Beaufort National Cemetery.

With a stay at The Meeting Street Inn, you'll be centrally located in Charleston, steps from Charleston City Market and Shops at Charleston Place.

Located in North Charleston (Ashley Heights), SpringHill Suites by Marriott Charleston N./Ashley Phosphate is within a 10-minute drive of Charleston Tanger Outlets and North Charleston Coliseum and Performing Arts Center.

With a stay at The Patricia Grand by Vacasa, you'll be centrally located in Myrtle Beach, steps from Myrtle Beach Beaches and 15 minutes by foot from Myrtle Beach Convention Center.

Located in Summerville, Spark by Hilton Summerville is within a 15-minute walk of North Main Market and Regal Azalea Square.

With a stay at Baymont by Wyndham Columbia Northwest in Columbia (Seven Oaks), you'll be within a 10-minute drive of University of South Carolina and Riverbanks Zoo and Garden.

With a stay at Aloft by Marriott Charleston Airport & Convention Center in North Charleston (Centre Pointe), you'll be within a 15-minute walk of Charleston Area Convention Center and North Charleston Coliseum and Performing Arts Center.