Compare Hotels with Air Conditioning in South Carolina

With a stay at The Francis Marion Hotel, you'll be centrally located in Charleston, steps from Marion Square and College of Charleston.

With a stay at Sea Mist Oceanfront Resort, you'll be centrally located in Myrtle Beach, within a 5-minute drive of Myrtle Beach Boardwalk and SkyWheel Myrtle Beach.

In the heart of Mount Pleasant, Days Inn by Wyndham Mt Pleasant-Charleston-Patriots Point is within a 5-minute drive of Patriots Point and USS Yorktown.

Sheraton Columbia Downtown Hotel is in the heart of Columbia, within a 5-minute walk of Columbia Museum of Art and South Carolina State House.

Located in Yemassee, Red Roof Inn Yemassee is in a rural location, within a 15-minute drive of Carolina Cider Company and Auldbrass.

In the heart of Myrtle Beach, Sandcastle Oceanfront Resort South Beach is within a 5-minute drive of Myrtle Beach State Park and Ripley's Believe It or Not.

With a stay at Howard Johnson by Wyndham Beaufort/Parris Island in Beaufort, you'll be near the airport, within a 15-minute drive of Marine Corps Recruit Depot Parris Island and Beaufort National Cemetery.

With a stay at The Meeting Street Inn, you'll be centrally located in Charleston, steps from Shops at Charleston Place and within a 5-minute walk of Charleston City Market.

When you stay at SpringHill Suites by Marriott Charleston N./Ashley Phosphate in North Charleston, you'll be in the business district, within a 10-minute drive of Charleston Tanger Outlets and North Charleston Coliseum and Performing Arts Center.

With a stay at The Patricia Grand, you'll be centrally located in Myrtle Beach, within a 5-minute drive of Myrtle Beach Boardwalk and SkyWheel Myrtle Beach.

Located in Summerville, Country Inn & Suites by Radisson, Summerville, SC is within a 5-minute drive of Nexton Square and Lowcountry Conference Center.

When you stay at Baymont by Wyndham Columbia Northwest in Columbia, you'll be in the business district, within a 10-minute drive of University of South Carolina and Riverbanks Zoo and Garden.