Compare Business Hotels in South Carolina

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Featured South Carolina Business Hotels

Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

2.5 out of 5
246 Congaree Road Greenville SC
$84 nightly
The price is $92 total per night
$92 total
Dec 13 - Dec 14
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Greenville, Comfort Inn Greenville - Haywood Mall is in a regional park, within a 5-minute drive of Haywood Mall and Bob Jones University.
Pool
Breakfast included
Hyatt Place Charleston Airport/Convention Center

Hyatt Place Charleston Airport/Convention Center

3 out of 5
3234 W Montague Ave North Charleston SC
$94 nightly
The price is $107 total per night
$107 total
Dec 25 - Dec 26
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in North Charleston, Hyatt Place Charleston Airport/Convention Center is in a shopping district, within a 5-minute drive of North Charleston Coliseum and Performing Arts Center and Charleston Tanger Outlets.
Sheraton Columbia Downtown Hotel

Sheraton Columbia Downtown Hotel

3.5 out of 5
1400 Main St Columbia SC
$116 nightly
The price is $130 total per night
$130 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Sheraton Columbia Downtown Hotel is in the heart of Columbia, within a 5-minute walk of Columbia Museum of Art and South Carolina State House.
Free WiFi
Air conditioning
Town & Country Inn and Suites

Town & Country Inn and Suites

3 out of 5
2008 Savannah Hwy Charleston SC
$139 nightly
The price is $158 total per night
$158 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Town & Country Inn and Suites in Charleston (West Ashley), you'll be within a 10-minute drive of North Charleston Coliseum and Performing Arts Center and Medical University of South Carolina.
Pool
Parking included
Sleep Inn at Greenville Convention Cente

Sleep Inn at Greenville Convention Cente

2.5 out of 5
231 N Pleasantburg Dr Greenville SC
$85 nightly
The price is $94 total per night
$94 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
A stay at Sleep Inn at Greenville Convention Cente places you in the heart of Greenville, within a 5-minute drive of Greenville Convention Center and Greenville Technical College.
Breakfast included
Parking included
La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood

3 out of 5
65 W Orchard Park Dr Greenville SC
$71 nightly
The price is $78 total per night
$78 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Greenville, La Quinta Inn & Suites by Wyndham Greenville Haywood is within a 15-minute drive of Bon Secours Wellness Arena and Prisma Health Greenville Memorial Hospital.
Pool
Breakfast included
Home2 Suites by Hilton Greenville Downtown

Home2 Suites by Hilton Greenville Downtown

3 out of 5
350 North Main Street Greenville SC
$107 nightly
The price is $118 total per night
$118 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
You'll be centrally located in Greenville with a stay at Home2 Suites by Hilton Greenville Downtown, within a 15-minute walk of Bon Secours Wellness Arena and The Peace Center.
Pool
Breakfast included
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

3 out of 5
40 W Orchard Park Dr Greenville SC
$86 nightly
The price is $94 total per night
$94 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Hyatt Place Greenville/Haywood in Greenville, you'll be near the airport, within a 5-minute drive of Haywood Mall and Bob Jones University.
Pool
Breakfast included
Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island

4 out of 5
130 Shipyard Drive Hilton Head Island SC
$212 nightly
The price is $233 total per night
$233 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Sonesta Resort Hilton Head Island in Hilton Head Island (South End), you'll be within a 15-minute drive of Coligny Beach and Palmetto Dunes Beach.
Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest

2.5 out of 5
347 Zimalcrest Drive Columbia SC
$80 nightly
The price is $89 total per night
$89 total
Dec 13 - Dec 14
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Baymont by Wyndham Columbia Northwest in Columbia (St. Andrews), you'll be within a 10-minute drive of Riverbanks Zoo and Garden and University of South Carolina.
Pool
Breakfast included
Country Inn & Suites by Radisson, Columbia, SC

Country Inn & Suites by Radisson, Columbia, SC

2.5 out of 5
220 E Exchange Blvd Columbia SC
$67 nightly
The price is $75 total per night
$75 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
With a stay at Country Inn & Suites by Radisson, Columbia, SC in Columbia, you'll be within a 10-minute drive of Fort Jackson and University of South Carolina.
Pool
Breakfast included
SpringHill Suites by Marriott Charleston N./Ashley Phosphate

SpringHill Suites by Marriott Charleston N./Ashley Phosphate

3 out of 5
7535 N Forest Drive North Charleston SC
$88 nightly
The price is $100 total per night
$100 total
Dec 16 - Dec 17
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at SpringHill Suites by Marriott Charleston N./Ashley Phosphate in North Charleston (Ashley Heights), you'll be within a 10-minute drive of North Charleston Coliseum and Performing Arts Center and Northwoods Mall.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

South Carolina Business Hotels essential information

 

Business Hotels in South Carolina

824

Highest price
$233
Cheapest price
$75
Total number of hotels in South Carolina
52,443
Popular hotels
Comfort Inn Greenville - Haywood Mall, Hyatt Place Charleston Airport/Convention Center, Sheraton Columbia Downtown Hotel, Town & Country Inn and Suites, Sleep Inn at Greenville Convention Cente, La Quinta Inn & Suites by Wyndham Greenville Haywood, Home2 Suites by Hilton Greenville Downtown, Hyatt Place Greenville/Haywood, Sonesta Resort Hilton Head Island, Baymont by Wyndham Columbia Northwest, Country Inn & Suites by Radisson, Columbia, SC, SpringHill Suites by Marriott Charleston N./Ashley Phosphate

 

Most Recent South Carolina Hotel Reviews

Hyatt Place Charleston/Historic District

Hyatt Place Charleston/Historic District

5 out of 5
Posted 1 day ago
CheapTickets Verified Review
"Clean room, staff very pleasant and attentive, location was perfect. Breakfast was good as well, cleaning staff in the breakfast area were paying attention to detail, cleaning and paying attentive. Front desk morning staff, very courteous especially Darnell. "
A verified traveler stayed at Hyatt Place Charleston/Historic District
Hyatt Place Charleston/Historic District

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