Compare Business Hotels in South Carolina
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Featured South Carolina Business Hotels
Comfort Inn Greenville - Haywood Mall
246 Congaree Road Greenville SC
$84 nightly
The price is $92 total per night
$92 total
Dec 12 - Dec 13
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Greenville, Comfort Inn Greenville - Haywood Mall is in a regional park, within a 5-minute drive of Haywood Mall and Bob Jones University.
Pool
Breakfast included
Hyatt Place Charleston Airport/Convention Center
3234 W Montague Ave North Charleston SC
$94 nightly
The price is $107 total per night
$107 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in North Charleston, Hyatt Place Charleston Airport/Convention Center is in a shopping district, within a 5-minute drive of North Charleston Coliseum and Performing Arts Center and Charleston Tanger Outlets.
Pool
Breakfast included
Sheraton Columbia Downtown Hotel
1400 Main St Columbia SC
$114 nightly
The price is $128 total per night
$128 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Sheraton Columbia Downtown Hotel is in the heart of Columbia, within a 5-minute walk of Columbia Museum of Art and South Carolina State House.
Free WiFi
Air conditioning
Town & Country Inn and Suites
2008 Savannah Hwy Charleston SC
$139 nightly
The price is $158 total per night
$158 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Town & Country Inn and Suites in Charleston (West Ashley), you'll be within a 10-minute drive of North Charleston Coliseum and Performing Arts Center and Medical University of South Carolina.
Pool
Parking included
Sleep Inn at Greenville Convention Cente
231 N Pleasantburg Dr Greenville SC
$104 nightly
The price is $115 total per night
$115 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Free Cancellation
A stay at Sleep Inn at Greenville Convention Cente places you in the heart of Greenville, within a 5-minute drive of Greenville Convention Center and Greenville Technical College.
Breakfast included
Parking included
La Quinta Inn & Suites by Wyndham Greenville Haywood
65 W Orchard Park Dr Greenville SC
$72 nightly
The price is $79 total per night
$79 total
Dec 15 - Dec 16
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Located in Greenville, La Quinta Inn & Suites by Wyndham Greenville Haywood is within a 15-minute drive of Bon Secours Wellness Arena and Prisma Health Greenville Memorial Hospital.
Pool
Breakfast included
Home2 Suites by Hilton Greenville Downtown
350 North Main Street Greenville SC
$107 nightly
The price is $118 total per night
$118 total
Dec 21 - Dec 22
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
You'll be centrally located in Greenville with a stay at Home2 Suites by Hilton Greenville Downtown, within a 15-minute walk of Bon Secours Wellness Arena and The Peace Center.
Pool
Breakfast included
Hyatt Place Greenville/Haywood
40 W Orchard Park Dr Greenville SC
$84 nightly
The price is $92 total per night
$92 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Hyatt Place Greenville/Haywood in Greenville, you'll be near the airport, within a 5-minute drive of Haywood Mall and Bob Jones University.
Sonesta Resort Hilton Head Island
130 Shipyard Drive Hilton Head Island SC
$212 nightly
The price is $233 total per night
$233 total
Dec 17 - Dec 18
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Sonesta Resort Hilton Head Island in Hilton Head Island (South End), you'll be within a 15-minute drive of Coligny Beach and Palmetto Dunes Beach.
Pool
Hot Tub
Baymont by Wyndham Columbia Northwest
347 Zimalcrest Drive Columbia SC
$60 nightly
The price is $67 total per night
$67 total
Dec 12 - Dec 13
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Baymont by Wyndham Columbia Northwest in Columbia (St. Andrews), you'll be within a 10-minute drive of Riverbanks Zoo and Garden and University of South Carolina.
Pool
Breakfast included
Country Inn & Suites by Radisson, Columbia, SC
220 E Exchange Blvd Columbia SC
$67 nightly
The price is $75 total per night
$75 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
With a stay at Country Inn & Suites by Radisson, Columbia, SC in Columbia, you'll be within a 10-minute drive of Fort Jackson and University of South Carolina.
Pool
Breakfast included
SpringHill Suites by Marriott Charleston N./Ashley Phosphate
7535 N Forest Drive North Charleston SC
$88 nightly
The price is $100 total per night
$100 total
Dec 15 - Dec 16
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at SpringHill Suites by Marriott Charleston N./Ashley Phosphate in North Charleston (Ashley Heights), you'll be within a 10-minute drive of North Charleston Coliseum and Performing Arts Center and Northwoods Mall.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South Carolina Business Hotels essential information
Business Hotels in South Carolina |
824 |
|---|---|
Highest price | $233 |
Cheapest price | $67 |
Total number of hotels in South Carolina | 52,443 |
Popular hotels | Comfort Inn Greenville - Haywood Mall, Hyatt Place Charleston Airport/Convention Center, Sheraton Columbia Downtown Hotel, Town & Country Inn and Suites, Sleep Inn at Greenville Convention Cente, La Quinta Inn & Suites by Wyndham Greenville Haywood, Home2 Suites by Hilton Greenville Downtown, Hyatt Place Greenville/Haywood, Sonesta Resort Hilton Head Island, Baymont by Wyndham Columbia Northwest, Country Inn & Suites by Radisson, Columbia, SC, SpringHill Suites by Marriott Charleston N./Ashley Phosphate |
Most Recent South Carolina Hotel Reviews
La Quinta Inn & Suites by Wyndham Myrtle Beach - N Kings Hwy
5 out of 5
Posted 2 days ago
CheapTickets Verified Review
"Yes"
A verified traveler from Clayton stayed at La Quinta Inn & Suites by Wyndham Myrtle Beach - N Kings Hwy
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