Compare Casino Resorts & Hotels in Panama
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Featured Panama Casino Resorts & Hotels

Waymore Hotel Spa and Casino
Via Veneto Y Avenida Eusebio Morales Panama City Panamá Province
With a stay at Waymore Hotel Spa and Casino in Panama City (Bella Vista), you'll be a 3-minute walk from Via Espana and within a 5-minute drive of Albrook Shopping Mall.
Pool
Spa

JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
$251 nightly
The price is $276 total per night
$276 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
Centrally located in Panama City, JW Marriott Panama is within a 15-minute walk of Multiplaza Pacific Mall and Avenida Balboa.
Pool
Spa

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
56 y 57 East Street, Obarrio Panama City Panama
$159 nightly
The price is $175 total per night
$175 total
Dec 20 - Dec 21
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Sortis Hotel, Spa & Casino, Autograph Collection by Marriott places you in the heart of Panama City, within a 15-minute walk of Via Espana and Avenida Balboa.
Pool
Spa

Decapolis Hotel Panama City
Avenida Balboa Con Multicentro Panama City Panama
$113 nightly
The price is $125 total per night
$125 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Decapolis Hotel Panama City, you'll be centrally located in Panama City, steps from Avenida Balboa and Multicentro Panama.
Pool
Breakfast included

Megapolis Hotel Panamá
Ave. Balboa al lado de Multicentro, 63 Panama City Panamá Province
With a stay at Megapolis Hotel Panamá, you'll be centrally located in Panama City, steps from Multicentro Panama and Avenida Balboa.
Hot Tub
All inclusive

Renaissance Panama City Hotel
Via España & Ricardo Arias Street Panama City Panama
$116 nightly
The price is $128 total per night
$128 total
Dec 20 - Dec 21
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
With a stay at Renaissance Panama City Hotel , you'll be centrally located in Panama City, steps from Via Espana and 11 minutes by foot from Avenida Balboa.
Pool
Parking included

Hilton Panama
Balboa Ave. and Aquilino De La Guardia Panama City
$186 nightly
The price is $205 total per night
$205 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Hilton Panama places you in the heart of Panama City, within a 5-minute drive of Multicentro Panama and Multiplaza Pacific Mall.
Pool
Spa

Hotel y Casino Central Park Panama
Calle Miguel Brostella Panama City Panama
$77 nightly
The price is $84 total per night
$84 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Hotel y Casino Central Park Panama places you in the heart of Panama City, within a 5-minute drive of El Dorado Mall and Metropolitan Nature Park.
Parking included
Free WiFi

Riande Aeropuerto Hotel & Casino
Vía Tocumen Tocumen Panama
$125 nightly
The price is $138 total per night
$138 total
Dec 14 - Dec 15
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Riande Aeropuerto Hotel & Casino in Tocumen, you'll be near the airport, within a 15-minute drive of Multiplaza Pacific Mall and Avenida Balboa.
Pool
Breakfast included

Grand Decameron Panama, A Trademark All Inclusive Resort
Avenida Principal Farallon Kilometro 115 Rio Hato Cocle
$247 nightly
The price is $272 total per night
$272 total
Dec 22 - Dec 23
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
When you stay at Grand Decameron Panama, A Trademark All Inclusive Resort in Rio Hato, you'll be on the beach, within a 15-minute drive of Playa Blanca and Farallón Beach.
Pool
All inclusive

The Saba Hotel
Panama Internacional zone,Argentina Ave Panama City Panama
With a stay at The Saba Hotel, you'll be centrally located in Panama City, within a 5-minute drive of Albrook Shopping Mall and Via Espana.
Parking included
Free WiFi

Radisson Colon 2,000 Hotel & Casino
Paseo Gorgas, Calle 13 Colon Colon
$88 nightly
The price is $97 total per night
$97 total
Dec 27 - Dec 28
Total with taxes and fees
Free Cancellation
Reserve now, pay when you stay
A stay at Radisson Colon 2,000 Hotel & Casino places you in the heart of Colon, steps from Colon 2000 and a 2-minute drive from Monument to Christopher Columbus.
Pool
Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Panama Casino Resorts & Hotels essential information
Casino Resorts & Hotels in Panama |
122 |
|---|---|
Highest price | $276 |
Cheapest price | $84 |
Total number of hotels in Panama | 3,584 |
Popular hotels | Waymore Hotel Spa and Casino, JW Marriott Panama, Sortis Hotel, Spa & Casino, Autograph Collection by Marriott, Decapolis Hotel Panama City, Megapolis Hotel Panamá, Renaissance Panama City Hotel , Hilton Panama, Hotel y Casino Central Park Panama, Riande Aeropuerto Hotel & Casino, Grand Decameron Panama, A Trademark All Inclusive Resort, The Saba Hotel, Radisson Colon 2,000 Hotel & Casino |
Most Recent Panama Hotel Reviews

Hotel Riu Plaza Panama
5 out of 5
Posted 3 days ago
CheapTickets Verified Review
"The Staff was Amazing. Pamela at the hotels store mad my fiancé and I feel like family. The rooms are spacious and clean. "
A verified traveler stayed at Hotel Riu Plaza Panama
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