See all 877 hotels in Depew
- Buffalo Airport Hotel
- Garden Place Hotel
- Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
- La Quinta Inn & Suites by Wyndham Buffalo Amherst
- Holiday Inn Express Grand Island - Niagara Falls by IHG
- Fairbridge Inn Express Buffalo Airport Williamsville
- The Delavan Hotel & Spa
- Buffalo Marriott Niagara
- DoubleTree by Hilton Hotel Buffalo - Amherst
- Hampton Inn Buffalo-Airport / Galleria Mall
- Red Roof Inn Buffalo - Niagara Airport
- The Westin Buffalo
- Crowne Plaza Niagara Falls NY Riverside by IHG
- Staybridge Suites Williamsville Buffalo by IHG
- Buffalo Guesthouse
- Woodland Inn
- Econo Lodge Darien Lakes