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Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

2.5 star property

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Photo gallery for Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

1 bedroom, in-room safe, desk, laptop workspace
A buffet with labeled containers of omelets and other dishes.
Business center
Lobby sitting area
Lobby sitting area

Reviews

8.6 out of 10
Excellent

Popular amenities

  • Free WiFi
  • Air conditioning
  • Gym
  • Business services
  • Laundry
The current price is $138
$119 nightly
$138 total
Total with taxes and fees
Aug 9 - Aug 10

Explore the area

View in a map
601 Main St, Buffalo, NY, 14203
  • Place, Shea's Performing Arts Center
    ‪2 min walk‬
  • Place, Fountain Plaza
    ‪2 min walk‬
  • Place, Buffalo Niagara Convention Center
    ‪6 min walk‬
  • Airport, Buffalo, NY (BUF-Buffalo Niagara Intl.)
    ‪22 min drive‬

Room options

View all photos for Standard Room

Standard Room | 1 bedroom, in-room safe, desk, laptop workspace

Standard Room

9.0 out of 10
Wonderful
(28 reviews)
  • 500 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom

Suite, 1 Bedroom | 1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom

8.8 out of 10
Excellent
(55 reviews)
  • City view
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

9.6 out of 10
Exceptional
(4 reviews)
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

9.0 out of 10
Wonderful
(4 reviews)
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free WiFi

DOUBLE Accessible-Queen Size Bed

  • Sleeps 4
  • Free WiFi

DOUBLE KING SIZE BED

  • Sleeps 4
  • Free WiFi

Room TWO BEDS

  • Sleeps 10
  • Free WiFi

Similar properties

Lobby
Wyndham Garden Buffalo Downtown
Downtown Buffalo
  • Breakfast included
  • Restaurant
  • Air conditioning
  • Gym
4.5 out of 5, Wonderful, 1,846 reviews
$149 nightly
The price is $173
Aug 5 - Aug 6
Total with taxes and fees
Wyndham Garden Buffalo Downtown

About the neighborhood

Buffalo

With a stay at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG in Buffalo (Downtown Buffalo), you'll be steps from Market Arcade Building and Buffalo Music Hall of Fame. .This hotel is 0.1 mi (0.1 km) from CEPA Gallery and 0.1 mi (0.2 km) from Road Less Traveled Productions.

What's nearby

  • Chippewa District - 1 min walk - 0.0 miles
  • Shea's Performing Arts Center - 2 min walk - 0.1 miles
  • Fountain Plaza - 2 min walk - 0.1 miles
  • Buffalo Niagara Convention Center - 6 min walk - 0.4 miles
  • Niagara Square - 8 min walk - 0.5 miles

Getting around

  • Fountain Plaza Station - 1 min walk
  • Buffalo-Exchange Street Station - 18 min walk
  • Buffalo Niagara Intl. Airport (BUF) - 21 min drive

Restaurants

  • ‪Tap House Pub & Grill - ‬4 min walk
  • ‪Big Ditch Brewing Company - ‬4 min walk
  • ‪Eddie Brady's - ‬3 min walk
  • ‪Lucky Day Whiskey Bar - ‬4 min walk
  • ‪Bada Bing - ‬2 min walk

About this property

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers 146 accommodations with safes and coffee/tea makers. Accommodations have separate sitting areas and are furnished with double sofa beds. Cable television is provided. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include shower/tub combinations, complimentary toiletries, and hair dryers.

This Buffalo hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily.

Recreational amenities at the hotel include a fitness center.
Make yourself at home in one of the 146 guestrooms featuring refrigerators and microwaves. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include safes and desks, as well as phones with free local calls.
Take advantage of recreation opportunities such as a fitness center, or other amenities including complimentary wireless internet access and a vending machine.
A complimentary buffet breakfast is served daily from 6:00 AM to 10:00 AM.
Featured amenities include a business center, express check-out, and dry cleaning/laundry services.
A complimentary buffet breakfast is served each morning between 6:00 AM and 10:00 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Offsite parking available (USD 16 per day)
  • Wheelchair-accessible parking and van parking available
  • Onsite parking options include a garage

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM

Things to do

  • Gym

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Laundry facilities
  • Living room
  • Separate bedroom

Conveniences

  • 24-hour front desk
  • Guidebooks
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Elevator
  • Grab bar in shower
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • In-room roll-in shower
  • Lever door handles
  • Low-height electrical outlets in bathroom
  • Portable shower seat
  • Raised toilet seat
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible bathroom vanity
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking

More

  • 7 floors
  • Comprehensive food waste policy
  • Eco-friendly cleaning products used
  • Smoking not allowed
  • Some LED lighting used
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 49-inch TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Restaurant dining guides

More

  • Air conditioning (climate-controlled)
  • Bulk dispensers for toiletries
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Living room
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed (service animals are welcome, and are exempt from fees)

Children and extra beds

Children are welcome
Children up to the age of 18 years can stay for free if using existing beds when occupying the parent or guardian's room
Rollaway/extra beds are not available
Free cribs are available on request at the property

Property payment types

Important information

Optional extras

  • Nearby parking fee: USD 16.00 per day (500 ft away)

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher, a smoke detector, and window guards
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property

We should mention

Only registered guests are allowed in the guestrooms
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Holiday Inn Express Buffalo Downtown Hotel
Comfort Suites Hotel Downtown
Comfort Suites Downtown Hotel Buffalo
Comfort Suites Downtown Buffalo
Comfort Suites Downtown Buffalo Hotel
Comfort Suites Buffalo
Buffalo Comfort Suites
Holiday Inn Express Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown Medical CTR
Holiday Inn Express Suites Buffalo Downtown Medical CTR by IHG

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

Reviews

8.6

Excellent

Rating 10 - Excellent. 557 out of 1000 reviews
Rating 8 - Good. 264 out of 1000 reviews
Rating 6 - Okay. 79 out of 1000 reviews
Rating 4 - Poor. 44 out of 1000 reviews
Rating 2 - Terrible. 56 out of 1000 reviews

8.8/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.6/10

Property conditions & facilities

Reviews

Verified

8/10 Good

Janine

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was great and staff was friendly and helpful.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Ben

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very well placed hotel for the theatre district in Buffalo as well as a few train stops down from where the Sabers play hockey. Great hotel and an awesome price!!
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

Scott

Great room and stay for the money.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great Stay All Around!!! Great Friendly Staff, Close To Everything AAAAA+++++
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Robert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Easy and safe area to walk around.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Jenny

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Was great
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Ellen

Liked: Cleanliness, staff & service, amenities
Very clean and friendly staff
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great service and great location
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Julie

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful room clean most comfortable bed I have ever slept in!
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Sharon

Liked: Cleanliness, amenities, property conditions & facilities
Rooms were very clean. Staff was very accommodating. Just very enjoyable stay.
Stayed 4 nights in Feb 2026
Verified

10/10 Excellent

Dharani

Liked: Cleanliness, amenities, property conditions & facilities
Clean room and staff are helpful
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Melissa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was just as pictured a one bedroom suite, clean, quiet hotel, parking garage was 2 short blocks down from the property reasonable pricing well lit, for being in the city felt very safe, not a lot of dining options close by, breakfast had a large variety. I would definitely stay again.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Theron

Big, spacious room and suite. Excellent location
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Stardeja

Liked: Cleanliness, amenities, property conditions & facilities
Great place! I will be back
Stayed 3 nights in Feb 2026
Verified

10/10 Excellent

Eden

Liked: Cleanliness, amenities, property conditions & facilities
Very clean and friendly
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Nick

Liked: Cleanliness, amenities, property conditions & facilities
Staff were helpful during a fire alarm and kept people relaxed.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Tim

Always a great experience, decades of staying here
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

Joseph

Liked: Cleanliness, staff & service, amenities
Good Stay All Around
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Giuseppe

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very close to the theatre where we got to watch Riverdance! Memorable experience.
Stayed 2 nights in Mar 2026
Verified

8/10 Good

Steve

Liked: Cleanliness, property conditions & facilities
Room was clean and lots of room, spacious.
Stayed 1 night in Feb 2026
Verified

8/10 Good

Scott

Liked: Cleanliness, amenities
Super friendly and curtious. Breakfast was awesome!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Daniel

Liked: Cleanliness, staff & service, property conditions & facilities
Clean, nice staff, good breakfast
Stayed 3 nights in Oct 2025
Verified

10/10 Excellent

RYAN

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Rooms were large. Breakfast was good and very friendly and helpful staff
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Adontaye

Liked: Cleanliness, amenities, property conditions & facilities
Everything was great!
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Mallory

Liked: Cleanliness, property conditions & facilities
The room was great and spacious
Stayed 1 night in Jan 2026