See all 603 hotels in Applegate
- Comfort Inn Medford North
- Quality Inn & Suites Medford Airport
- Hilton Garden Inn Medford, OR
- Hampton Inn & Suites Grants Pass
- City Center Motel
- Pine Tree Inn
- Relax Inn of Medford
- Charleen's Cottage~Couple Perfect!Great Location! A Gem!
- Modern 1 BR Guest House in Central Point, OR. Your ideal Southern Oregon stopover! Features AC, full kitchen, W/D, and dedicated workspace. Quick and convenient access to I-5 and local attractions.
- Farmhouse Bliss Escape to Nature
- Charming Wine Country Carriage House – 2BR/2BA near Jacksonville Peaceful retreat in the heart of Southern Oregon wine country. Private, comfy, and perfect for couples or friends. Close to wineries, trails & historic Jacksonville.
- Tiny Living at its Finest… 🐞
- WoodSpring Suites Medford near I-5
- Lovely-5 bedroom historic Inn